Term Name: pneumocandin B0
Synonyms: (10R,12S)-N-{(2R,6S,9S,11R,12R,14aS,15S,20S,23S,25aS)-20-[(1R)-3-amino-1-hydroxy-3-oxopropyl]-23-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,12,15-tetrahydroxy-6-[(1R)-1-hydroxyethyl]-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1, L 688,786, L-688,786, L-688786, pneumocandin B(0), pneumocardin B(0)
Definition: An echinocandin initially isolated as a very minor bioactive fermentation product of Glarea lozoyensis (originally known as Zalerion arboricola). Subsequent random mutagenesis work and optimisation of the fermentation medium permitted the industrial production of pneumocandin B0, which is used as the starting point for the synthesis of the antifungal drug caspofungin.
Ontology: ChEBI [CHEBI:131609]  ( EBI )

Relationships
is a type of: echinocandin homodetic cyclic peptide
has_role: antifungal agent fungal metabolite
inverse has_functional_parent: caspofungin