| Term: | keratinocyte keratin filament |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | keratinocyte |
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| Synonyms: | keratinocytes |
| Definition: | An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell. |
| Ontology: | Anatomy Ontology [ZFA:0009158] |
| Name: | keratin filament |
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| Synonyms: | acidic keratin, basic/neutral keratin |
| Definition: | A filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. The keratins are the most diverse classes of IF proteins, with a large number of keratin isoforms being expressed. Each type of epithelium always expresses a characteristic combination of type I and type II keratins. |
| Ontology: | GO: Cellular Component [GO:0045095] QuickGO AmiGO |