Term: neural plate border neural crest cell
Note: This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name.
Name: neural plate border
Definition: Region of the neural plate that will give rise to the neural crest. The neural plate border includes progenitors for the dorsal neural tube, the neural crest, and placodes. It is a broad competence domain, established between neural and non-neural ectoderm within which subtle and sequential cell autonomous and non-cell autonomous molecular interactions will progressively define the neural crest fate from adjacent dorsal neural fates.
Ontology: Anatomy Ontology [ZFA:0007082]
Name: neural crest cell
Synonyms: neural crest cells
Definition: A cell of the neural crest. The neural crest is a strip of specialized ectoderm, the neural plate border, which flanks each side of the embryonic neural plate. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesenchymal transition and delamination to form migratory neural crest cells. Most of the cranial and all of the spinal sensory ganglion cells arise by differentiation of neural crest cells.
Ontology: Anatomy Ontology [ZFA:0009165]