Term: retinal pigmented epithelium adherens junction
Note: This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name.
Name: retinal pigmented epithelium
Synonyms: pigmented epithelium, pigmented retina, pigmented retinal epithelium, PRE, RPE
Definition: A monolayer of pigmented epithelium covering the neural retina; develops from the outer of the two layers of the optic cup.
Ontology: Anatomy Ontology [ZFA:0000144]
Name: adherens junction
Synonyms: cell-cell adherens junction
Definition: A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules.
Ontology: GO: Cellular Component [GO:0005912]   QuickGO   AmiGO