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Term: otic vesicle epithelial to mesenchymal transition
Note: This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name.
Name: otic vesicle
Synonyms: otic capsule, otocyst, ov
Definition: Epithelial sac present beside the fifth rhombomere; forms the semicircular canals dorsally and the otolith organs ventrally, and houses the acoustico-vestibular sensory epithelia (maculae) of hair cells. (Also see Anatomical Atlas entry for ear by T. Whitfield.)
Ontology: Anatomy Ontology [ZFA:0000051]
Name: epithelial to mesenchymal transition
Synonyms: EMT, epithelial-mesenchymal transition, mesenchymal cell differentiation from epithelial cell
Definition: A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
Ontology: GO: Biological Process [GO:0001837]   QuickGO   AmiGO