Name: | keratinocyte |
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Synonyms: | keratinocytes |
Definition: | An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell. |
Ontology: | Anatomy Ontology [ZFA:0009158] |
Name: | caspase complex |
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Synonyms: | cysteine-type endopeptidase complex |
Definition: | A protein complex that contains one or more cysteine-type endopeptidases (also called caspases), which give the complex a peptidase activity with specificity for the hydrolysis of aspartyl bonds. These complexes may be involved e.g. in apoptotic or inflammation processes. |
Ontology: | GO: Cellular Component [GO:0008303] QuickGO AmiGO |