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General Information
ZIRC
ZFIN ID: ZDB-GENE-990415-127
Gene Name: SIX homeobox 3a
Gene Symbol: six3a
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function DNA binding IEA InterPro:IPR001356 ZFIN Electronic Annotation
DNA binding IEA InterPro:IPR009057 ZFIN Electronic Annotation
DNA binding IEA UniProtKB-KW:KW-0238 ZFIN Electronic Annotation
DNA binding IEA UniProtKB-KW:KW-0371 ZFIN Electronic Annotation
DNA-binding transcription factor activity, RNA polymerase II-specific IBA PANTHER:PTN000044272, MGI:MGI:106034, MGI:MGI:102778, FB:FBgn0003460, MGI:MGI:102764, UniProtKB:Q15475 Gaudet et al., 2010
DNA-binding transcription factor activity, RNA polymerase II-specific IEA InterPro:IPR032949 ZFIN Electronic Annotation
transcription regulatory region sequence-specific DNA binding IBA PANTHER:PTN000044272, dictyBase:DDB_G0272967 Gaudet et al., 2010
Cellular Component nucleus IBA PANTHER:PTN000044272, RGD:620906, MGI:MGI:106034, WB:WBGene00006775, MGI:MGI:102778, WB:WBGene00000455, FB:FBgn0003460, WB:WBGene00000453, MGI:MGI:102764, UniProtKB:Q15475, MGI:MGI:102780, MGI:MGI:106220 Gaudet et al., 2010
nucleus IEA UniProtKB-KW:KW-0539 ZFIN Electronic Annotation
transcription factor complex IBA PANTHER:PTN000044272, MGI:MGI:102780 Gaudet et al., 2010
Biological Process anatomical structure development IBA PANTHER:PTN000044272, MGI:MGI:106034, FB:FBgn0025360, MGI:MGI:102778, MGI:MGI:102764, MGI:MGI:102780, MGI:MGI:106220 Gaudet et al., 2010
brain development IBA MGI:MGI:102764, PANTHER:PTN002571848 Gaudet et al., 2010
brain development IEA InterPro:IPR032949 ZFIN Electronic Annotation
brain development IMP MO1-six3a,six3b Ando et al., 2005
eye development IBA MGI:MGI:102764, UniProtKB:O95343, PANTHER:PTN002470536 Gaudet et al., 2010
eye development IEA InterPro:IPR032949 ZFIN Electronic Annotation
negative regulation of transcription, DNA-templated IBA MGI:MGI:106034, PANTHER:PTN000044272, MGI:MGI:102764, UniProtKB:O95343, MGI:MGI:102780, MGI:MGI:106220, RGD:620909 Gaudet et al., 2010
optic nerve development IGI six3b Samuel et al., 2016
optic nerve morphogenesis IGI six3b Samuel et al., 2016
regulation of transcription, DNA-templated IEA InterPro:IPR032949 ZFIN Electronic Annotation