ZFIN ID: ZDB-GENE-980526-485
Gene Name: POU domain, class 5, transcription factor 3
Gene Symbol: pou5f3
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function chromatin binding IDA Kotkamp et al., 2014
chromatin binding IDA part_of(nucleosome organization) Veil et al., 2019
DNA binding IEA InterPro:IPR001356 ZFIN Electronic Annotation
DNA binding IEA InterPro:IPR009057 ZFIN Electronic Annotation
DNA binding IEA InterPro:IPR010982 ZFIN Electronic Annotation
DNA binding IEA InterPro:IPR013847 ZFIN Electronic Annotation
DNA binding IEA UniProtKB-KW:KW-0238 ZFIN Electronic Annotation
DNA binding IEA UniProtKB-KW:KW-0371 ZFIN Electronic Annotation
DNA-binding transcription activator activity, RNA polymerase II-specific IBA RGD:3367, UniProtKB:Q15319, UniProtKB:Q12837, FB:FBgn0085424, UniProtKB:Q9UKI9, PANTHER:PTN000180816, MGI:MGI:97588, MGI:MGI:102525, MGI:MGI:101897, MGI:MGI:102524, FB:FBgn0004394, MGI:MGI:101895, MGI:MGI:101893, FB:FBgn0086680 Gaudet et al., 2010
DNA-binding transcription factor activity IEA InterPro:IPR000327 ZFIN Electronic Annotation
DNA-binding transcription factor activity IGI sox32 Reim et al., 2004
protein heterodimerization activity IPI vox Zhao et al., 2013
protein heterodimerization activity IPI sox32 Zhao et al., 2013
sequence-specific DNA binding IDA Leichsenring et al., 2013
sequence-specific DNA binding IEA InterPro:IPR017970 ZFIN Electronic Annotation
sequence-specific DNA binding IPI sox19b Leichsenring et al., 2013
sequence-specific DNA binding IPI bambia Leichsenring et al., 2013
sequence-specific DNA binding IPI nanog Leichsenring et al., 2013
sequence-specific DNA binding IPI sox2 Leichsenring et al., 2013
sequence-specific DNA binding IPI sox19a Leichsenring et al., 2013
sequence-specific DNA binding IPI sox3 Leichsenring et al., 2013
sequence-specific DNA binding IPI pou5f3 Leichsenring et al., 2013
sequence-specific DNA binding IPI foxd5 Leichsenring et al., 2013
Cellular Component nucleus IBA RGD:3367, UniProtKB:Q12837, UniProtKB:Q06416, UniProtKB:Q01860, UniProtKB:Q9UKI9, PANTHER:PTN000180816, UniProtKB:A7Y7W2, MGI:MGI:102935, RGD:621690, RGD:1359491, WB:WBGene00000441, RGD:61947, RGD:61946, FB:FBgn0086680, UniProtKB:Q03052, UniProtKB:Q15319, UniProtKB:P20264, UniProtKB:P28069, RGD:619767, RGD:619768, UniProtKB:P14859, MGI:MGI:97588, WB:WBGene00006818, UniProtKB:P09086, MGI:MGI:101898, MGI:MGI:102525, MGI:MGI:102524, MGI:MGI:101897, MGI:MGI:101896, MGI:MGI:102523, WB:WBGene00000431, FB:FBgn0004394, MGI:MGI:101895, MGI:MGI:102564, MGI:MGI:101893, RGD:621689, UniProtKB:Q14863 Gaudet et al., 2010
nucleus IEA UniProtKB-KW:KW-0539 ZFIN Electronic Annotation
Biological Process anatomical structure morphogenesis IMP pou5f3hi349Tg Reim et al., 2002
anatomical structure morphogenesis IMP pou5f3e713/e713 Reim et al., 2002
brain development IMP pou5f3hi349Tg Reim et al., 2002
brain development IMP pou5f3e713/e713 Reim et al., 2002
brain development IMP pou5f3wi270Tg Wiellette et al., 2004
brain segmentation IMP pou5f3m793/m793 (AB) Hauptmann et al., 2002
brain segmentation IMP pou5f3m216/m216 (AB) Hauptmann et al., 2002
cell differentiation IBA FB:FBgn0085424, UniProtKB:Q01860, RGD:619767, FB:FBgn0000028, PANTHER:PTN000180816, MGI:MGI:97588, WB:WBGene00006818, UniProtKB:A0A0B4JD55, MGI:MGI:102525, MGI:MGI:102524, MGI:MGI:101897, MGI:MGI:102523, MGI:MGI:101896, WB:WBGene00000431, FB:FBgn0004394, MGI:MGI:101895, WB:WBGene00000441, MGI:MGI:101894, MGI:MGI:102565, MGI:MGI:101893, MGI:MGI:102564, FB:FBgn0086680 Gaudet et al., 2010
dorsal/ventral pattern formation IMP pou5f3hi349Tg/hi349Tg Reim et al., 2006
ectoderm development IMP pou5f3hi349Tg Reim et al., 2002
ectoderm development IMP pou5f3e713/e713 Reim et al., 2002
embryonic pattern specification IMP pou5f3hi349Tg Reim et al., 2002
embryonic pattern specification IMP pou5f3e713/e713 Reim et al., 2002
embryonic pattern specification IMP pou5f3hi349Tg/hi349Tg Riley et al., 2004
endoderm formation IMP pou5f3m793/m793 (AB) Lunde et al., 2004
endoderm formation IMP pou5f3hi349Tg Reim et al., 2004
epiboly IMP pou5f3m793/m793 Song et al., 2013
epiboly involved in gastrulation with mouth forming second IMP pou5f3m793/m793 (AB) Lachnit et al., 2008
epiboly involved in gastrulation with mouth forming second IMP pou5f3hi349Tg/hi349Tg Lachnit et al., 2008
epiboly involved in gastrulation with mouth forming second IMP pou5f3m793/+ (AB) Lachnit et al., 2008
fin regeneration IMP MO1-pou5f3 Christen et al., 2010
hindbrain development IMP pou5f3m793/m793 (AB) Hauptmann et al., 2002
hindbrain development IMP pou5f3m216/m216 (AB) Hauptmann et al., 2002
mesoderm development IMP pou5f3hi349Tg Reim et al., 2002
mesoderm development IMP pou5f3e713/e713 Reim et al., 2002
midbrain-hindbrain boundary development IMP pou5f3m216/m216 (AB) Schier et al., 1996
morphogenesis of embryonic epithelium IMP pou5f3hi349Tg Reim et al., 2002
morphogenesis of embryonic epithelium IMP pou5f3e713/e713 Reim et al., 2002
multicellular organism development IEA UniProtKB-KW:KW-0217 ZFIN Electronic Annotation
nucleosome organization IDA Veil et al., 2019
positive regulation of transcription by RNA polymerase II IBA RGD:3367, UniProtKB:Q12837, UniProtKB:Q01860, UniProtKB:Q9UKI9, FB:FBgn0000028, PANTHER:PTN000180816, FB:FBgn0086680, UniProtKB:Q15319, UniProtKB:P28069, FB:FBgn0085424, RGD:619767, UniProtKB:Q01851, UniProtKB:P14859, RGD:619768, MGI:MGI:97588, WB:WBGene00006818, MGI:MGI:102525, MGI:MGI:101898, MGI:MGI:102524, MGI:MGI:101897, MGI:MGI:102523, FB:FBgn0004394, MGI:MGI:101895, MGI:MGI:102565, MGI:MGI:101893, MGI:MGI:102564 Gaudet et al., 2010
positive regulation of transcription, DNA-templated IGI sox32 Reim et al., 2004
regulation of DNA methylation IGI MO1-pou5f3, apchu745/hu745 Rai et al., 2010
regulation of endodermal cell fate specification IGI vox, sox32 Zhao et al., 2013
regulation of endodermal cell fate specification IGI sox32 Zhao et al., 2013
regulation of gene expression IMP pou5f3m793/m793 Kotkamp et al., 2014
regulation of transcription, DNA-templated IEA InterPro:IPR000327 ZFIN Electronic Annotation
regulation of transcription, DNA-templated IEA InterPro:IPR017970 ZFIN Electronic Annotation