Gene

pou3f1

ID

ZDB-GENE-980526-372

Name

POU class 3 homeobox 1

Symbol

pou3f1 Nomenclature History

Previous Names

Oct-6 (1)
oct6 (1)
pou50
wu:fc09d06
zp-50
zp50
zp50pou

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific. Predicted to be involved in cell differentiation and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in several structures, including forebrain neural rod; hindbrain neural keel; nervous system; neural plate; and presumptive diencephalon. Orthologous to human POU3F1 (POU class 3 homeobox 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

36 figures from 16 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

eu433 (22 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Zhang et al., 2020
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pou3f1 Human Ortholog

No data available

Associated With pou3f1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017970	Homeobox, conserved site
Domain	IPR000327	POU-specific domain
Domain	IPR001356	Homeobox domain
Domain	IPR013847	POU domain
Family	IPR016362	POU-domain transcription factor, class 3
Homologous_superfamily	IPR009057	Homeobox-like domain superfamily
Homologous_superfamily	IPR010982	Lambda repressor-like, DNA-binding domain superfamily