ZFIN ID: ZDB-GENE-980526-178
Gene Name: fibroblast growth factor 3
Gene Symbol: fgf3
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function fibroblast growth factor receptor binding IDA Kiefer et al., 1996
fibroblast growth factor receptor binding IEA InterPro:IPR028232 ZFIN Electronic Annotation
growth factor activity IEA InterPro:IPR002209 ZFIN Electronic Annotation
growth factor activity IEA UniProtKB-KW:KW-0339 ZFIN Electronic Annotation
Cellular Component extracellular matrix IDA Kiefer et al., 1996
extracellular region IEA InterPro:IPR028232 ZFIN Electronic Annotation
extracellular region IEA UniProtKB-KW:KW-0964 ZFIN Electronic Annotation
extracellular space IDA Kiefer et al., 1996
Biological Process adenohypophysis development IMP MO1-fgf3 Liu et al., 2008
anterior/posterior pattern specification IGI hnf1ba, fgf8a Hernandez et al., 2004
cartilage development IMP Crump et al., 2004
cartilage development IMP MO1-fgf3 2 Publications
cell differentiation IEA UniProtKB-KW:KW-0221 ZFIN Electronic Annotation
cell fate specification IGI chrdunspecified Kudoh et al., 2004
cell fate specification IMP 2 Publications
dorsal/ventral pattern formation IMP 3 Publications
ectodermal placode development IGI fgf3t26212/t26212 , MO2-fgf10b, MO3-fgf10b Maulding et al., 2014
embryonic neurocranium morphogenesis IGI fgf8a McCarthy et al., 2016
embryonic pattern specification IGI ctnnb2p1 Maegawa et al., 2006
embryonic retina morphogenesis in camera-type eye IGI MO1-fgf24, fgf3t24149/t24149; fgf8ati282a/ti282a Picker et al., 2009
fibroblast growth factor receptor signaling pathway IEA InterPro:IPR028232 ZFIN Electronic Annotation
hindbrain development IMP Wiellette et al., 2004
inner ear morphogenesis IMP Williams et al., 2004
locus ceruleus development IGI MO2-fgf8a, MO1-fgf8a, MO4-fgf3 Nechiporuk et al., 2007
midbrain development IGI MO3-fgf8a, MO1-fgf3 Miyake et al., 2013
multicellular organism development IEA UniProtKB-KW:KW-0217 ZFIN Electronic Annotation
negative regulation of apoptotic process IMP fgf3unspecified Herzog et al., 2004
neural crest cell development IMP MO1-fgf3 Lin et al., 2013
neurohypophysis development IMP fgf3t24152/t24152; s896Tg Liu et al., 2013
neuron development IGI cnot8m1061/m1061; fgf3t24152/t24152 Koch et al., 2014
neuron fate specification IGI MO3-fgf8a, MO1-fgf3 Miyake et al., 2005
oligodendrocyte differentiation IGI MO3-fgf8a, MO1-fgf3 Miyake et al., 2005
otic placode formation IGI fgf8a Dougan et al., 2003
otic placode formation IGI fgf3t24149/t24149 , MO1-wnt8b Hans et al., 2007
otic placode formation IMP 2 Publications
otic placode formation IMP fgf3t24149/t24149 Hans et al., 2007
otic vesicle development IGI fgf3t26212/t26212 , MO2-fgf10b, MO3-fgf10b Maulding et al., 2014
otic vesicle formation IGI fgf8a Solomon et al., 2004
otic vesicle formation IMP Phillips et al., 2004
otolith development IGI hnf1bahi2169Tg/hi2169Tg , fgf3t24149/t24149 Hans et al., 2007
peripheral nervous system development IGI MO2-fgf8a, MO1-fgf8a, MO4-fgf3 Nechiporuk et al., 2007
peripheral nervous system development IGI fgf3t24149/t24149; fgf8ati282a/ti282a Nechiporuk et al., 2007
positive regulation of cell division IEA UniProtKB-KW:KW-0497 ZFIN Electronic Annotation
positive regulation of cell migration IGI fgf8ati282a/ti282a Crump et al., 2004
positive regulation of neurogenesis IMP MO4-fgf3 Nechiporuk et al., 2005
positive regulation of neuron differentiation IGI bmp2b Kudoh et al., 2004
positive regulation of neuron differentiation IMP Kudoh et al., 2004
positive regulation of Wnt signaling pathway IGI fgf8a Phillips et al., 2004
posterior lateral line neuromast primordium migration IGI fgf10atbvbo/tbvbo; fgf3t24149/t24149; zf106Tg Lecaudey et al., 2008
retina development in camera-type eye IGI fgf3unspecified/unspecified; fgf8aunspecified/unspecified Martinez-Morales et al., 2005
rhombomere 5 development IGI MO3-fgf8a, MO5-fgf3 Wiellette et al., 2003
rhombomere 6 development IGI MO3-fgf8a, MO5-fgf3 Wiellette et al., 2003
skeletal system development IMP Williams et al., 2004
NOT thyroid gland development IMP fgf3t24149/t24149 (TU) Alt et al., 2006
vestibular receptor cell development IMP fgf3t24152/t24152 Kwak et al., 2006