Gene
cers3b
- ID
- ZDB-GENE-080220-32
- Name
- ceramide synthase 3b
- Symbol
- cers3b Nomenclature History
- Previous Names
-
- cers3
- zgc:171494
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have sphingosine N-acyltransferase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to localize to endoplasmic reticulum. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 9. Is expressed in several structures, including digestive system; otic placode; otic vesicle; pectoral fin; and pronephric duct. Orthologous to human CERS3 (ceramide synthase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive congenital ichthyosis 9 | Alliance | Ichthyosis, congenital, autosomal recessive 9 | 615023 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Homeobox domain | Homeobox-like domain superfamily | Sphingosine N-acyltransferase Lag1/Lac1-like | TRAM/LAG1/CLN8 homology domain |
|---|---|---|---|---|---|
|
UniProtKB:A8WFT1
|
351 | ||||
|
UniProtKB:A0A8M2B5K0
|
349 | ||||
|
UniProtKB:A0A8M9PF77
|
183 | ||||
|
UniProtKB:A0A8M2B5Y1
|
366 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| aberrant processed transcript |
cers3b-202
(1)
|
Havana | 1108 nt | |
| mRNA |
cers3b-201
(1)
|
Havana | 1598 nt |
Interactions and Pathways
No data available
Plasmids
No data available