ZFIN ID: ZDB-GENE-060503-539
Gene Name: natriuretic peptide receptor 1a
Gene Symbol: npr1a
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function ATP binding IEA InterPro:IPR000719 ZFIN Electronic Annotation
guanylate cyclase activity IBA MGI:MGI:106025, UniProtKB:P20594, RGD:620439, RGD:2771, RGD:620438, RGD:3195, MGI:MGI:106903, FB:FBgn0266136, WB:WBGene00001538, WB:WBGene00020131, MGI:MGI:97372, MGI:MGI:97371, UniProtKB:P16066, WB:WBGene00001535, PANTHER:PTN000229249 Gaudet et al., 2010
guanylate cyclase activity IEA EC:4.6.1.2 ZFIN Electronic Annotation
guanylate cyclase activity IEA InterPro:IPR011645 ZFIN Electronic Annotation
lyase activity IEA UniProtKB-KW:KW-0456 ZFIN Electronic Annotation
natriuretic peptide receptor activity IBA MGI:MGI:97372, UniProtKB:P20594, PANTHER:PTN000228929, UniProtKB:P16066 Gaudet et al., 2010
nucleotide binding IEA UniProtKB-KW:KW-0547 ZFIN Electronic Annotation
peptide hormone binding IBA UniProtKB:P20594, PANTHER:PTN000228929, UniProtKB:P16066, RGD:620851 Gaudet et al., 2010
peptide receptor activity IBA UniProtKB:P20594, MGI:MGI:97372, RGD:69322, UniProtKB:P16066, FB:FBgn0266136, PANTHER:PTN000229249 Gaudet et al., 2010
phosphorus-oxygen lyase activity IEA InterPro:IPR018297 ZFIN Electronic Annotation
protein kinase activity IEA InterPro:IPR000719 ZFIN Electronic Annotation
protein kinase activity IEA InterPro:IPR001245 ZFIN Electronic Annotation
Cellular Component integral component of membrane IEA InterPro:IPR001170 ZFIN Electronic Annotation
integral component of membrane IEA UniProtKB-KW:KW-0812 ZFIN Electronic Annotation
membrane IEA UniProtKB-KW:KW-0472 ZFIN Electronic Annotation
plasma membrane IBA UniProtKB:P20594, RGD:620439, RGD:69322, RGD:620438, RGD:3195, UniProtKB:F1MRI0, PANTHER:PTN000228925, RGD:620851 Gaudet et al., 2010
plasma membrane IBA MGI:MGI:106025, UniProtKB:P20594, RGD:620439, RGD:69322, RGD:620438, RGD:3195, UniProtKB:F1MRI0, PANTHER:PTN001728782, RGD:620851, UniProtKB:P9WQ35 Gaudet et al., 2010
Biological Process cardiac muscle cell proliferation IMP MO9-nrp1a, MO1-npr2 Becker et al., 2014
cGMP biosynthetic process IBA MGI:MGI:105123, MGI:MGI:106025, UniProtKB:P20594, RGD:620439, UniProtKB:P55203, RGD:620438, RGD:2771, dictyBase:DDB_G0275009, RGD:3195, MGI:MGI:106903, FB:FBgn0266136, WB:WBGene00001538, MGI:MGI:97372, WB:WBGene00020131, RGD:69322, MGI:MGI:97371, UniProtKB:Q02846, UniProtKB:P16066, UniProtKB:F1MRI0, WB:WBGene00001535, PANTHER:PTN000229249 Gaudet et al., 2010
cGMP biosynthetic process IEA InterPro:IPR011645 ZFIN Electronic Annotation
cGMP biosynthetic process IEA UniProtKB-KW:KW-0141 ZFIN Electronic Annotation
cyclic nucleotide biosynthetic process IEA InterPro:IPR001054 ZFIN Electronic Annotation
cyclic nucleotide biosynthetic process IEA InterPro:IPR018297 ZFIN Electronic Annotation
intracellular signal transduction IEA InterPro:IPR001054 ZFIN Electronic Annotation
intracellular signal transduction IEA InterPro:IPR018297 ZFIN Electronic Annotation
protein phosphorylation IEA InterPro:IPR000719 ZFIN Electronic Annotation
protein phosphorylation IEA InterPro:IPR001245 ZFIN Electronic Annotation
receptor guanylyl cyclase signaling pathway IBA UniProtKB:P20594, UniProtKB:P16066, PANTHER:PTN000229249 Gaudet et al., 2010
signal transduction IBA WB:WBGene00003848, WB:WBGene00000907, RGD:3195, dictyBase:DDB_G0274569, PANTHER:PTN001728782 Gaudet et al., 2010