ZFIN ID: ZDB-GENE-060222-1
Gene Name: prostaglandin E receptor 4 (subtype EP4) a
Gene Symbol: ptger4a
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function G protein-coupled receptor activity IEA InterPro:IPR000276 ZFIN Electronic Annotation
G protein-coupled receptor activity IEA UniProtKB-KW:KW-0297 ZFIN Electronic Annotation
prostaglandin E receptor activity IBA RGD:628641, UniProtKB:P35408, PANTHER:PTN002627505 Gaudet et al., 2010
prostaglandin E receptor activity IDA Tsuge et al., 2013
prostaglandin E receptor activity IEA InterPro:IPR001758 ZFIN Electronic Annotation
prostaglandin receptor activity IEA InterPro:IPR001244 ZFIN Electronic Annotation
Cellular Component integral component of membrane IEA InterPro:IPR000276 ZFIN Electronic Annotation
integral component of membrane IEA InterPro:IPR001244 ZFIN Electronic Annotation
integral component of membrane IEA InterPro:IPR001758 ZFIN Electronic Annotation
integral component of membrane IEA InterPro:IPR008365 ZFIN Electronic Annotation
integral component of membrane IEA InterPro:IPR017452 ZFIN Electronic Annotation
integral component of membrane IEA UniProtKB-KW:KW-0812 ZFIN Electronic Annotation
membrane IEA UniProtKB-KW:KW-0472 ZFIN Electronic Annotation
plasma membrane IBA MGI:MGI:97795, MGI:MGI:102966, RGD:3435, UniProtKB:P43088, PANTHER:PTN002627442, RGD:628641, UniProtKB:P21731, UniProtKB:Q13258, RGD:3825, UniProtKB:P43119 Gaudet et al., 2010
Biological Process adenylate cyclase-activating G protein-coupled receptor signaling pathway IBA MGI:MGI:97794, MGI:MGI:97793, MGI:MGI:99535, PANTHER:PTN000933518, UniProtKB:P43119 Gaudet et al., 2010
cell migration involved in gastrulation IMP MO1-ptger4a Cha et al., 2006
cell migration involved in gastrulation IMP MO2-ptger4a Cha et al., 2006
cellular response to prostaglandin E stimulus IBA RGD:628641, PANTHER:PTN002627505 Gaudet et al., 2010
embryonic liver development IGI MO2-ptger4a, MO1-ptger4a, MO2-ptger2a, MO1-ptger2a Nissim et al., 2014
embryonic liver development IMP MO2-ptger4a, MO1-ptger4a Nissim et al., 2014
exocrine pancreas development IGI MO2-ptger4a, MO1-ptger4a, MO2-ptger2a, MO1-ptger2a Nissim et al., 2014
exocrine pancreas development IMP MO2-ptger4a, MO1-ptger4a Nissim et al., 2014
G protein-coupled receptor signaling pathway IEA InterPro:IPR000276 ZFIN Electronic Annotation
G protein-coupled receptor signaling pathway IEA InterPro:IPR001244 ZFIN Electronic Annotation
G protein-coupled receptor signaling pathway IEA InterPro:IPR001758 ZFIN Electronic Annotation
G protein-coupled receptor signaling pathway IEA InterPro:IPR008365 ZFIN Electronic Annotation
G protein-coupled receptor signaling pathway IEA UniProtKB-KW:KW-0297 ZFIN Electronic Annotation
hematopoietic progenitor cell differentiation IMP MO1-ptger4a Villablanca et al., 2007
hematopoietic progenitor cell differentiation IMP MO2-ptger4a Villablanca et al., 2007
inflammatory response IBA MGI:MGI:98496, MGI:MGI:102966, PANTHER:PTN000933518 Gaudet et al., 2010
negative regulation of inflammatory response IBA MGI:MGI:104311, UniProtKB:P35408, PANTHER:PTN002627505 Gaudet et al., 2010
positive regulation of cytosolic calcium ion concentration IBA MGI:MGI:97795, RGD:3435, RGD:3825, PANTHER:PTN000933518 Gaudet et al., 2010
pronephros development IMP MO1-ptger4a Poureetezadi et al., 2016
signal transduction IEA UniProtKB-KW:KW-0807 ZFIN Electronic Annotation
T cell differentiation in thymus IMP MO2-ptger4a Villablanca et al., 2007
T cell differentiation in thymus IMP MO3-ptger4a Villablanca et al., 2007