Gene
traf3
- ID
- ZDB-GENE-040801-257
- Name
- TNF receptor-associated factor 3
- Symbol
- traf3 Nomenclature History
- Previous Names
-
- zgc:92367 (1)
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have tumor necrosis factor receptor binding activity; ubiquitin protein ligase binding activity; and ubiquitin-protein transferase activity. Involved in response to yeast. Predicted to localize to cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in brain disease. Orthologous to human TRAF3 (TNF receptor associated factor 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92367 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {?Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 5} | 614849 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017907 | Zinc finger, RING-type, conserved site |
| Domain | IPR001293 | Zinc finger, TRAF-type |
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR002083 | MATH/TRAF domain |
| Domain | IPR027128 | TNF receptor-associated factor 3, C3HC3D-type RING zinc finger |
| Domain | IPR037304 | TNF receptor-associated factor 3, MATH domain |
| Domain | IPR049342 | TRAF1-6/MEP1A/B-like, MATH domain |
| Domain | IPR049440 | TNF receptor-associated factor 3/5, RING domain |
| Family | IPR012227 | TNF receptor-associated factor TRAF, metazoa |
| Homologous_superfamily | IPR008974 | TRAF-like |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Domain Details Per Protein
| Protein | Length | MATH/TRAF domain | TNF receptor-associated factor 3/5, RING domain | TNF receptor-associated factor 3, C3HC3D-type RING zinc finger | TNF receptor-associated factor 3, MATH domain | TNF receptor-associated factor TRAF, metazoa | TRAF1-6/MEP1A/B-like, MATH domain | TRAF-like | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, RING-type, conserved site | Zinc finger, TRAF-type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6DEG0
|
573 | |||||||||||
|
UniProtKB:A0A8M9PKN5
|
546 |
Interactions and Pathways
No data available
Plasmids
No data available