Gene

ppp3cca

ID

ZDB-GENE-030829-36

Name

protein phosphatase 3, catalytic subunit, gamma isozyme, a

Symbol

ppp3cca Nomenclature History

Previous Names

ppp3cc
PPP3CCa (1)
sb:cb767
si:dkey-21k4.5 (1)

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have calmodulin binding activity and calmodulin-dependent protein phosphatase activity. Predicted to be involved in calcineurin-mediated signaling. Predicted to localize to calcineurin complex and cytoplasm. Human ortholog(s) of this gene implicated in schizophrenia. Is expressed in several structures, including hatching gland; musculature system; nervous system; polster; and trigeminal placode. Orthologous to human PPP3CC (protein phosphatase 3 catalytic subunit gamma).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

cb767 (17 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ppp3cca Human Ortholog

No data available

Associated With ppp3cca Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004843	Calcineurin-like phosphoesterase domain, ApaH type
Domain	IPR006186	Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
Domain	IPR041751	PP2B, metallophosphatase domain
Family	IPR043360	PP2B
Homologous_superfamily	IPR029052	Metallo-dependent phosphatase-like