Gene

nampt2

ID
ZDB-GENE-030131-2931
Name
nicotinamide phosphoribosyltransferase 2
Symbol
nampt2 Nomenclature History
Previous Names
  • namptb (1)
  • im:7051384
  • wu:fc21g12
  • wu:fc27h03
  • wu:fd15d03
  • zgc:55764
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have cytokine activity; nicotinamide phosphoribosyltransferase activity; and nicotinate-nucleotide diphosphorylase (carboxylating) activity. Predicted to be involved in NAD biosynthetic process and circadian regulation of gene expression. Predicted to localize to cytoplasm; extracellular space; and nucleus. Human ortholog(s) of this gene implicated in transient cerebral ischemia. Orthologous to human NAMPT (nicotinamide phosphoribosyltransferase).
Genome Resources
Note
This gene name was updated because the phylogenetic tree indicates this was the result of a duplication event PRIOR to the divergence of ray- and lobe-fin fishes and not the teleost WGD
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nampt2 Human Ortholog
No data available
Associated With nampt2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR041525 Nicotinate/nicotinamide phosphoribosyltransferase
Domain IPR041529 Nicotinamide phosphoribosyltransferase, N-terminal domain
Family IPR016471 Nicotinamide phosphoribosyl transferase
Homologous_superfamily IPR013785 Aldolase-type TIM barrel
Homologous_superfamily IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal
Domain Details Per Protein
Protein Length Aldolase-type TIM barrel Nicotinamide phosphoribosyl transferase Nicotinamide phosphoribosyltransferase, N-terminal domain Nicotinate/nicotinamide phosphoribosyltransferase Nicotinate phosphoribosyltransferase-like, C-terminal
UniProtKB:F1RDZ8 498
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations