UniProt ID: B0S6A5 |
SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}. |
UniProt ID: Q6DGH9 |
FUNCTION: Involved in the specification of isotocin cells. Required for the specification of dopaminergic neurons in the developing hypothalamus and posterior tuberculum. {ECO:0000269|PubMed:17180684, ECO:0000269|PubMed:17481897}. SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00138, ECO:0000269|PubMed:17180684}. TISSUE SPECIFICITY: Isoform 1 and isoform 2 are expressed in brain and testis. {ECO:0000269|PubMed:17074092}. DEVELOPMENTAL STAGE: Isoform 1 and isoform 2 are expressed during embryonic development. At 16 hpf, expressed in a few cells in the ventral dieencephalon. At 48 hpf, present in the preoptic area and ventral hypothalamus (at protein level). {ECO:0000269|PubMed:17074092, ECO:0000269|PubMed:17180684}. MISCELLANEOUS: [Isoform 2]: Characteristic of the fish lineage. {ECO:0000305}. SIMILARITY: Belongs to the paired homeobox family. Bicoid subfamily. {ECO:0000305}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |