UniProt ID: Q6DGH9
FUNCTION: Involved in the specification of isotocin cells. Required for the specification of dopaminergic neurons in the developing hypothalamus and posterior tuberculum. {ECO:0000269|PubMed:17180684, ECO:0000269|PubMed:17481897}.
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00138, ECO:0000269|PubMed:17180684}.
TISSUE SPECIFICITY: Isoform 1 and isoform 2 are expressed in brain and testis. {ECO:0000269|PubMed:17074092}.
DEVELOPMENTAL STAGE: Isoform 1 and isoform 2 are expressed during embryonic development. At 16 hpf, expressed in a few cells in the ventral dieencephalon. At 48 hpf, present in the preoptic area and ventral hypothalamus (at protein level). {ECO:0000269|PubMed:17074092, ECO:0000269|PubMed:17180684}.
SIMILARITY: Belongs to the paired homeobox family. Bicoid subfamily. {ECO:0000305}.
UniProt ID: A0A2R8Q301
SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE- ProRule:PRU00138, ECO:0000256|RuleBase:RU000682, ECO:0000256|SAAS:SAAS00868163}.
SIMILARITY: Belongs to the paired homeobox family. {ECO:0000256|SAAS:SAAS00864608}.
UniProt ID: B0S6A5
SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE- ProRule:PRU00138, ECO:0000256|RuleBase:RU000682, ECO:0000256|SAAS:SAAS00868163}.
SIMILARITY: Belongs to the paired homeobox family. {ECO:0000256|SAAS:SAAS00864608}.
This information was provided by UniProt through a collaboration with ZFIN. (1)