UniProt ID: Q90477 |
FUNCTION: May act as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. {ECO:0000250}. SUBUNIT: Efficient DNA binding requires dimerization with another bHLH protein. INTERACTION: Q90477; Q90463: her1; NbExp=2; IntAct=EBI-16009646, EBI-16009629; Q90477; Q9I9K1: her7; NbExp=2; IntAct=EBI-16009646, EBI-16009727; Q90477; Q6P0J1: hes6; NbExp=2; IntAct=EBI-16009646, EBI-16009592; SUBCELLULAR LOCATION: Nucleus. TISSUE SPECIFICITY: From mid-gastrula to just before somite formation, expressed in cells adjacent to axial mesoderm. Subsequently, during the anterior-to-posterior wave of somite formation and maturation, expressed within particular regions of each somite. Expressed in both muscle and non-muscle cells. {ECO:0000269|PubMed:12524040, ECO:0000269|PubMed:8565839}. |
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