| UniProt ID: A0A0R4IFJ4 |
| FUNCTION: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. {ECO:0000256|PIRNR:PIRNR001594}. CATALYTIC ACTIVITY: Reaction=ATP + hydrogencarbonate + pyruvate = ADP + H(+) + oxaloacetate + phosphate; Xref=Rhea:RHEA:20844, ChEBI:CHEBI:15361, ChEBI:CHEBI:15378, ChEBI:CHEBI:16452, ChEBI:CHEBI:17544, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=6.4.1.1; Evidence={ECO:0000256|PIRNR:PIRNR001594}; COFACTOR: Name=biotin; Xref=ChEBI:CHEBI:57586; Evidence={ECO:0000256|ARBA:ARBA00001953, ECO:0000256|PIRNR:PIRNR001594}; PATHWAY: Carbohydrate biosynthesis; gluconeogenesis. {ECO:0000256|ARBA:ARBA00004742}. |
| This information was provided by UniProt through a collaboration with ZFIN. (1) |