UniProt ID: Q32LU4 |
FUNCTION: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. {ECO:0000256|ARBA:ARBA00002600, ECO:0000256|RuleBase:RU367069}. CATALYTIC ACTIVITY: Reaction=3 O2 + protoporphyrinogen IX = 3 H2O2 + protoporphyrin IX; Xref=Rhea:RHEA:25576, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240, ChEBI:CHEBI:57306, ChEBI:CHEBI:57307; EC=1.3.3.4; Evidence={ECO:0000256|ARBA:ARBA00000672, ECO:0000256|RuleBase:RU367069}; COFACTOR: Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000256|RuleBase:RU367069}; Note=Binds 1 FAD per subunit. {ECO:0000256|RuleBase:RU367069}; PATHWAY: Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrin-IX from protoporphyrinogen-IX: step 1/1. {ECO:0000256|ARBA:ARBA00005073, ECO:0000256|RuleBase:RU367069}. SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000256|RuleBase:RU367069}. SIMILARITY: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily. {ECO:0000256|ARBA:ARBA00010551, ECO:0000256|RuleBase:RU367069}. |
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