UniProt ID: Q6DC93 |
FUNCTION: Calcium-binding protein that acts as an adapter that bridges unrelated proteins or stabilizes weak protein-protein complexes in response to calcium. Acts as a negative regulator of ER-Golgi transport (By similarity). {ECO:0000250|UniProtKB:Q641Z8, ECO:0000250|UniProtKB:Q9UBV8}. SUBUNIT: Heterodimer; heterodimerizes (via the EF-hand 5) with pdcd6. {ECO:0000250|UniProtKB:Q9UBV8}. SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9UBV8}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q641Z8}. Membrane {ECO:0000250|UniProtKB:Q9UBV8}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9UBV8}. Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000250|UniProtKB:Q9UBV8}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9UBV8}. |
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