UniProt ID: Q6P0U9 |
FUNCTION: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. {ECO:0000250}. SUBUNIT: Probable component of the nuclear pore complex (NPC). SUBCELLULAR LOCATION: Nucleus, nuclear pore complex {ECO:0000250|UniProtKB:O15504}. Nucleus membrane {ECO:0000250|UniProtKB:O15504}; Peripheral membrane protein {ECO:0000250|UniProtKB:O15504}; Cytoplasmic side {ECO:0000250|UniProtKB:O15504}. DOMAIN: The FG repeats are interaction sites for karyopherins (importins, exportins) and form probably an affinity gradient, guiding the transport proteins unidirectionally with their cargo through the NPC. {ECO:0000250}. |
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