UniProt ID: Q6PEI4 |
FUNCTION: Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. {ECO:0000256|PIRNR:PIRNR000932}. CATALYTIC ACTIVITY: Reaction=H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate; Xref=Rhea:RHEA:10684, Rhea:RHEA-COMP:10136, Rhea:RHEA- COMP:10137, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474, ChEBI:CHEBI:46858, ChEBI:CHEBI:82620; EC=3.1.3.48; Evidence={ECO:0000256|PIRNR:PIRNR000932}; SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR000932}. SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non- receptor class 4 subfamily. {ECO:0000256|ARBA:ARBA00034734, ECO:0000256|PIRNR:PIRNR000932}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |