UniProt ID: Q7T2F6 |
FUNCTION: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000250}. PATHWAY: Protein modification; protein ubiquitination. SUBUNIT: Component of a probable ECS E3 ubiquitin-protein ligase complex that contains the Elongin BC complex. {ECO:0000250}. DOMAIN: The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes. {ECO:0000250}. |
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