UniProt ID: Q504H8 |
FUNCTION: Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence (By similarity). {ECO:0000250}. SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}. TISSUE SPECIFICITY: Expressed in the ear placode and vesicle and in cells forming the vestibulo-acoustic ganglion. Also expressed in the lateral line. {ECO:0000269|PubMed:11025218}. INDUCTION: Regulated by fgf3 and fgf8 in otic vesicle. {ECO:0000269|PubMed:11025218, ECO:0000269|PubMed:12399318}. SIMILARITY: Belongs to the HMX homeobox family. {ECO:0000305}. |
UniProt ID: F1QMB1 |
SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}. |
UniProt ID: A0A8M2B544 |
SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |