UniProt ID: Q8AXV6 |
FUNCTION: Transcriptional repressor which functions as a downstream effector of Notch signaling. {ECO:0000250|UniProtKB:Q9WV93}. SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00380, ECO:0000255|PROSITE-ProRule:PRU00981}. DEVELOPMENTAL STAGE: Expressed following gastrulation. At the 1-somite stage, expressed in the paraxial mesoderm. Subsequently expressed in the telencephalon, the otic vesicles, the somites and the anterior presomitic mesoderm. {ECO:0000269|PubMed:14593478}. INDUCTION: Expression in the developing embryo is induced by activation of the Notch signaling pathway. {ECO:0000269|PubMed:14593478}. SIMILARITY: Belongs to the HEY family. {ECO:0000305}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |