ZFIN

ZFIN ID: ZDB-MRPHLNO-051026-3

ZFIN ID: ZDB-MRPHLNO-051026-3

CITATIONS (28 total)

Morpholino Name:	MO1-smn1
Morpholino Symbol:	MO1-smn1

Koh, A., Sarusie, M.V., Ohmer, J., Fischer, U., Winkler, C., Wohland, T. (2021) Fluorescence Correlation Spectroscopy Reveals Survival Motor Neuron Oligomerization but No Active Transport in Motor Axons of a Zebrafish Model for Spinal Muscular Atrophy. Frontiers in cell and developmental biology. 9:639904

Tay, S.H., Ellieyana, E.N., Le, Y., Sarusie, M.V., Grimm, C., Ohmer, J., Mathuru, A., Fischer, U., Winkler, C. (2021) A novel zebrafish model for intermediate type spinal muscular atrophy demonstrates importance of Smn for maintenance of mature motor neurons. Human molecular genetics. 30(24):2488-2502

Janzen, E., Mendoza-Ferreira, N., Hosseinibarkooie, S., Schneider, S., Hupperich, K., Tschanz, T., Grysko, V., Riessland, M., Hammerschmidt, M., Rigo, F., Bennett, C.F., Kye, M.J., Torres-Benito, L., Wirth, B. (2018) CHP1 reduction ameliorates spinal muscular atrophy pathology by restoring calcineurin activity and endocytosis. Brain : a journal of neurology. 141(8):2343-2361

Boyd, P.J., Tu, W.Y., Shorrock, H.K., Groen, E.J.N., Carter, R.N., Powis, R.A., Thomson, S.R., Thomson, D., Graham, L.C., Motyl, A.A.L., Wishart, T.M., Highley, J.R., Morton, N.M., Becker, T., Becker, C.G., Heath, P.R., Gillingwater, T.H. (2017) Bioenergetic status modulates motor neuron vulnerability and pathogenesis in a zebrafish model of spinal muscular atrophy. PLoS Genetics. 13:e1006744

Riessland, M., Kaczmarek, A., Schneider, S., Swoboda, K.J., Löhr, H., Bradler, C., Grysko, V., Dimitriadi, M., Hosseinibarkooie, S., Torres-Benito, L., Peters, M., Upadhyay, A., Biglari, N., Kröber, S., Hölker, I., Garbes, L., Gilissen, C., Hoischen, A., Nürnberg, G., Nürnberg, P., Walter, M., Rigo, F., Bennett, C.F., Kye, M.J., Hart, A.C., Hammerschmidt, M., Kloppenburg, P., Wirth, B. (2017) Neurocalcin Delta Suppression Protects against Spinal Muscular Atrophy in Humans and across Species by Restoring Impaired Endocytosis. American journal of human genetics. 100(2):297-315

Hosseinibarkooie, S., Peters, M., Torres-Benito, L., Rastetter, R.H., Hupperich, K., Hoffmann, A., Mendoza-Ferreira, N., Kaczmarek, A., Janzen, E., Milbradt, J., Lamkemeyer, T., Rigo, F., Bennett, C.F., Guschlbauer, C., Büschges, A., Hammerschmidt, M., Riessland, M., Kye, M.J., Clemen, C.S., Wirth, B. (2016) The Power of Human Protective Modifiers: PLS3 and CORO1C Unravel Impaired Endocytosis in Spinal Muscular Atrophy and Rescue SMA Phenotype. American journal of human genetics. 99(3):647-65

Powis, R.A., Karyka, E., Boyd, P., Côme, J., Jones, R.A., Zheng, Y., Szunyogova, E., Groen, E.J., Hunter, G., Thomson, D., Wishart, T.M., Becker, C.G., Parson, S.H., Martinat, C., Azzouz, M., Gillingwater, T.H. (2016) Systemic restoration of UBA1 ameliorates disease in spinal muscular atrophy. JCI insight. 1:e87908

Spiró, Z., Koh, A., Tay, S., See, K., Winkler, C. (2016) Transcriptional enhancement of Smn levels in motoneurons is crucial for proper axon morphology in zebrafish. Scientific Reports. 6:27470

Edens, B.M., Ajroud-Driss, S., Ma, L., Ma, Y.C. (2015) Molecular Mechanisms and Animal Models of Spinal Muscular Atrophy. Biochimica et biophysica acta. Molecular basis of disease. 1852(4):685-692

McGovern, V.L., Massoni-Laporte, A., Wang, X., Le, T.T., Le, H.T., Beattie, C.E., Rich, M.M., Burghes, A.H. (2015) Plastin 3 Expression Does Not Modify Spinal Muscular Atrophy Severity in the ∆7 SMA Mouse. PLoS One. 10:e0132364

Miller, N., Feng, Z., Edens, B.M., Yang, B., Shi, H., Sze, C.C., Hong, B.T., Su, S.C., Cantu, J.A., Topczewski, J., Crawford, T.O., Ko, C.P., Sumner, C.J., Ma, L., Ma, Y.C. (2015) Non-aggregating tau phosphorylation by cyclin-dependent kinase 5 contributes to motor neuron degeneration in spinal muscular atrophy. The Journal of neuroscience : the official journal of the Society for Neuroscience. 35:6038-50

Lyon, A.N., Pineda, R.H., Hao, L.T., Kudryashova, E., Kudryashov, D.S., and Beattie, C.E. (2014) Calcium binding is essential for plastin 3 function in Smn-deficient motoneurons. Human molecular genetics. 23(8):1990-2004

See, K., Yadav, P., Giegerich, M., Cheong, P.S., Graf, M., Vyas, H., Lee, S.G., Mathavan, S., Fischer, U., Sendtner, M., and Winkler, C. (2014) SMN deficiency alters Nrxn2 expression and splicing in zebrafish and mouse models of spinal muscular atrophy. Human molecular genetics. 23(7):1754-70

Sleigh, J.N., Barreiro-Iglesias, A., Oliver, P.L., Biba, A., Becker, T., Davies, K.E., Becker, C.G., and Talbot, K. (2014) Chondrolectin affects cell survival and neuronal outgrowth in in vitro and in vivo models of spinal muscular atrophy. Human molecular genetics. 23(4):855-69

Wiley, D.J., Juan, I., Le, H., Cai, X., Baumbach, L., Beattie, C., D'Urso, G. (2014) Yeast Augmented Network Analysis (YANA): a new systems approach to identify therapeutic targets for human genetic diseases. F1000Research. 3:121

Wishart, T.M., Mutsaers, C.A., Riessland, M., Reimer, M.M., Hunter, G., Hannam, M.L., Eaton, S.L., Fuller, H.R., Roche, S.L., Somers, E., Morse, R., Young, P.J., Lamont, D.J., Hammerschmidt, M., Joshi, A., Hohenstein, P., Morris, G.E., Parson, S.H., Skehel, P.A., Becker, T., Robinson, I.M., Becker, C.G., Wirth, B., Gillingwater, T.H. (2014) Dysregulation of ubiquitin homeostasis and beta-catenin signaling promote spinal muscular atrophy. J. Clin. Invest.. 124:1821-34

Gassman, A., Hao le, T., Bhoite, L., Bradford, C.L., Chien, C.B., Beattie, C.E, and Manfredi, J.P. (2013) Small molecule suppressors of Drosophila Kinesin deficiency rescue motor axon development in a zebrafish model of spinal muscular atrophy. PLoS One. 8(9):e74325

Hao, L.T., Wolman, M., Granato, M., and Beattie, C.E. (2012) Survival motor neuron affects plastin 3 protein levels leading to motor defects. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(15):5074-5084

Lotti, F., Imlach, W.L., Saieva, L., Beck, E.S., Hao le, T., Li, D.K., Jiao, W., Mentis, G.Z., Beattie, C.E., McCabe, B.D., and Pellizzoni, L. (2012) An SMN-Dependent U12 Splicing Event Essential for Motor Circuit Function. Cell. 151(2):440-454

Van Hoecke, A., Schoonaert, L., Lemmens, R., Timmers, M., Staats, K.A., Laird, A.S., Peeters, E., Philips, T., Goris, A., Dubois, B., Andersen, P.M., Al-Chalabi, A., Thijs, V., Turnley, A.M., van Vught, P.W., Veldink, J.H., Hardiman, O., Van Den Bosch, L., Gonzalez-Perez, P., Van Damme, P., Brown, R.H., van den Berg, L.H., and Robberecht, W. (2012) EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans. Nature medicine. 18(9):1418-1422

Akten, B., Kye, M.J., Hao, L.T., Wertz, M.H., Singh, S., Nie, D., Huang, J., Merianda, T.T., Twiss, J.L., Beattie, C.E., Steen, J.A., and Sahin, M. (2011) Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits. Proceedings of the National Academy of Sciences of the United States of America. 108(25):10337-42

Chitramuthu, B.P., Baranowski, D.C., Kay, D.G., Bateman, A., and Bennett, H.P. (2010) Progranulin modulates zebrafish motoneuron development in vivo and rescues truncation defects associated with knockdown of Survival motor neuron 1. Molecular neurodegeneration. 5:41

Strzelecka, M., Oates, A.C., and Neugebauer, K.M. (2010) Dynamic control of Cajal body number during zebrafish embryogenesis. Nucleus (Austin, Tex.). 1(1):96-108

McWhorter, M.L., Boon, K.L., Horan, E.S., Burghes, A.H., and Beattie, C.E. (2008) The SMN binding protein gemin2 is not involved in motor axon outgrowth. Developmental Neurobiology. 68(2):182-194

Oprea, G.E., Kröber, S., McWhorter, M.L., Rossoll, W., Müller, S., Krawczak, M., Bassell, G.J., Beattie, C.E., and Wirth, B. (2008) Plastin 3 is a protective modifier of autosomal recessive spinal muscular atrophy. Science (New York, N.Y.). 320(5875):524-527

Carrel, T.L., McWhorter, M.L., Workman, E., Zhang, H., Wolstencroft, E.C., Lorson, C., Bassell, G.J., Burghes, A.H., and Beattie, C.E. (2006) Survival motor neuron function in motor axons is independent of functions required for small nuclear ribonucleoprotein biogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. 26(43):11014-11022

Winkler, C., Eggert, C., Gradl, D., Meister, G., Giegerich, M., Wedlich, D., Laggerbauer, B., and Fischer, U. (2005) Reduced U snRNP assembly causes motor axon degeneration in an animal model for spinal muscular atrophy. Genes & Development. 19(19):2320-2330

McWhorter, M.L., Monani, U.R., Burghes, A.H., and Beattie, C.E. (2003) Knockdown of the survival motor neuron (Smn) protein in zebrafish causes defects in motor axon outgrowth and pathfinding. The Journal of cell biology. 162(5):919-932