ZFIN

ZFIN ID: ZDB-EREGION-110816-9

ZFIN ID: ZDB-EREGION-110816-9

CITATIONS (57 total)

Engineered Region Name:	FRT
Engineered Region Symbol:	FRT

Cardeira-da-Silva, J., Bensimon-Brito, A., Tarasco, M., Brandão, A.S., Rosa, J.T., Borbinha, J., Almeida, P.J., Jacinto, A., Cancela, M.L., Gavaia, P.J., Stainier, D.Y.R., Laizé, V. (2022) Fin ray branching is defined by TRAP⁺ osteolytic tubules in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 119:e2209231119e2209231119

Ethiraj, L.P., Fong, E.L.S., Liu, R., Chan, M., Winkler, C., Carney, T.J. (2022) Colorimetric and fluorescent TRAP assays for visualising and quantifying fish osteoclast activity. European journal of histochemistry : EJH. 66(2)

Hernández-Bejarano, M., Gestri, G., Monfries, C., Tucker, L., Dragomir, E.I., Bianco, I.H., Bovolenta, P., Wilson, S.W., Cavodeassi, F. (2022) Foxd1-dependent induction of a temporal retinal character is required for visual function. Development (Cambridge, England). 149(24):

Miao, K.Z., Cozzone, A., Caetano-Lopes, J., Harris, M.P., Fisher, S. (2022) Osteoclast activity sculpts craniofacial form to permit sensorineural patterning in the zebrafish skull. Frontiers in endocrinology. 13:969481

Poudel, S., Martins, G., Cancela, M.L., Gavaia, P.J. (2022) Resveratrol-Mediated Reversal of Doxorubicin-Induced Osteoclast Differentiation. International Journal of Molecular Sciences. 23(23):

Watson, C.J., Tang, W.J., Rojas, M.F., Fiedler, I.A.K., Morfin Montes de Oca, E., Cronrath, A.R., Callies, L.K., Swearer, A.A., Ahmed, A.R., Sethuraman, V., Addish, S., Farr, G.H., Gómez, A.E., Rai, J., Monstad-Rios, A.T., Gardiner, E.M., Karasik, D., Maves, L., Busse, B., Hsu, Y.H., Kwon, R.Y. (2022) wnt16 regulates spine and muscle morphogenesis through parallel signals from notochord and dermomyotome. PLoS Genetics. 18:e1010496

Moreno-Mármol, T., Ledesma-Terrón, M., Tabanera, N., Martin-Bermejo, M.J., Cardozo, M.J., Cavodeassi, F., Bovolenta, P. (2021) Stretching of the retinal pigment epithelium contributes to zebrafish optic cup morphogenesis. eLIFE. 10:

Ogawa, M., Geng, F.S., Humphreys, D.T., Kristianto, E., Sheng, D.Z., Hui, S.P., Zhang, Y., Sugimoto, K., Nakayama, M., Zheng, D., Hesselson, D., Hodson, M.P., Bogdanovic, O., Kikuchi, K. (2021) Krüppel-like factor 1 is a core cardiomyogenic trigger in zebrafish. Science (New York, N.Y.). 372:201-205

Caetano-Lopes, J., Henke, K., Urso, K., Duryea, J., Charles, J.F., Warman, M.L., Harris, M.P. (2020) Unique and non-redundant function of csf1r paralogues in regulation and evolution of post-embryonic development of the zebrafish. Development (Cambridge, England). 147(2):

Gu, S., Li, J., Li, S., Cao, J., Bu, J., Ren, Y., Du, W., Chen, Z., Xu, C., Wang, M., Jiang, L., Huang, C., Du, J. (2020) Efficient replacement of long DNA fragments via non-homologous end joining at non-coding regions. Journal of molecular cell biology. 13(1):75-77

Lee, H.J., Hou, Y., Chen, Y., Dailey, Z.Z., Riddihough, A., Jang, H.S., Wang, T., Johnson, S.L. (2020) Regenerating zebrafish fin epigenome is characterized by stable lineage-specific DNA methylation and dynamic chromatin accessibility. Genome biology. 21:52

Wong, E.S., Zheng, D., Tan, S.Z., Bower, N.L., Garside, V., Vanwalleghem, G., Gaiti, F., Scott, E., Hogan, B.M., Kikuchi, K., McGlinn, E., Francois, M., Degnan, B.M. (2020) Deep conservation of the enhancer regulatory code in animals. Science (New York, N.Y.). 370(6517):

Bertolini, J.A., Favaro, R., Zhu, Y., Pagin, M., Ngan, C.Y., Wong, C.H., Tjong, H., Vermunt, M.W., Martynoga, B., Barone, C., Mariani, J., Cardozo, M.J., Tabanera, N., Zambelli, F., Mercurio, S., Ottolenghi, S., Robson, P., Creyghton, M.P., Bovolenta, P., Pavesi, G., Guillemot, F., Nicolis, S.K., Wei, C.L. (2019) Mapping the Global Chromatin Connectivity Network for Sox2 Function in Neural Stem Cell Maintenance. Cell Stem Cell. 24:462-476.e6

Light, S.E.W., Jontes, J.D. (2019) Multiplane calcium imaging reveals disrupted development of network topology in zebrafish pcdh19 mutants. eNeuro. 6(3):

González-Rosa, J.M., Sharpe, M., Field, D., Soonpaa, M.H., Field, L.J., Burns, C.E., Burns, C.G. (2018) Myocardial Polyploidization Creates a Barrier to Heart Regeneration in Zebrafish. Developmental Cell. 44:433-446.e7

Grajevskaja, V., Camerota, D., Bellipanni, G., Balciuniene, J., Balciunas, D. (2018) Analysis of a conditional gene trap reveals that tbx5a is required for heart regeneration in zebrafish. PLoS One. 13:e0197293

Torbey, P., Thierion, E., Collombet, S., de Cian, A., Desmarquet-Trin-Dinh, C., Dura, M., Concordet, J.P., Charnay, P., Gilardi-Hebenstreit, P. (2018) Cooperation, cis-interactions, versatility and evolutionary plasticity of multiple cis-acting elements underlie krox20 hindbrain regulation. PLoS Genetics. 14:e1007581

Yuan, X., Song, M., Devine, P., Bruneau, B.G., Scott, I.C., Wilson, M.D. (2018) Heart enhancers with deeply conserved regulatory activity are established early in zebrafish development. Nature communications. 9:4977

Baltrunaite, K., Craig, M.P., Palencia Desai, S., Chaturvedi, P., Pandey, R.N., Hegde, R.S., Sumanas, S. (2017) ETS transcription factors Etv2 and Fli1b are required for tumor angiogenesis. Angiogenesis. 20(3):307-323

Chiang, I.K., Fritzsche, M., Pichol-Thievend, C., Neal, A., Holmes, K., Lagendijk, A., Overman, J., D'Angelo, D., Omini, A., Hermkens, D., Lesieur, E., Liu, K., Ratnayaka, I., Corada, M., Bou-Gharios, G., Carroll, J., Dejana, E., Schulte-Merker, S., Hogan, B., Beltrame, M., De Val, S., Francois, M. (2017) SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development. Development (Cambridge, England). 144(14):2629-2639

Justice, C.M., Kim, J., Kim, S.D., Kim, K., Yagnik, G., Cuellar, A., Carrington, B., Lu, C.L., Sood, R., Boyadjiev, S.A., Wilson, A.F. (2017) A variant associated with sagittal nonsyndromic craniosynostosis alters the regulatory function of a non-coding element. American journal of medical genetics. Part A. 173(11):2893-2897

Liu, H., Leslie, E.J., Carlson, J.C., Beaty, T.H., Marazita, M.L., Lidral, A.C., Cornell, R.A. (2017) Identification of common non-coding variants at 1p22 that are functional for non-syndromic orofacial clefting. Nature communications. 8:14759

Shah, M.H., Tabanera, N., Krishnadas, S.R., Pillai, M.R., Bovolenta, P., Sundaresan, P. (2017) Identification and characterization of variants and a novel 4 bp deletion in the regulatory region of SIX6, a risk factor for primary open-angle glaucoma.. Molecular genetics & genomic medicine. 5:323-335

Sugimoto, K., Hui, S.P., Sheng, D.Z., Kikuchi, K. (2017) Dissection of zebrafish shha function using site-specific targeting with a Cre-dependent genetic switch.. eLIFE. 6

Antosova, B., Smolikova, J., Klimova, L., Lachova, J., Bendova, M., Kozmikova, I., Machon, O., Kozmik, Z. (2016) The Gene Regulatory Network of Lens Induction Is Wired through Meis-Dependent Shadow Enhancers of Pax6. PLoS Genetics. 12:e1006441

Jungke, P., Hans, S., Gupta, M., Machate, A., Zöller, D., Brand, M. (2016) Generation of a conditional lima1a allele in zebrafish using the FLEx switch technology. Genesis (New York, N.Y. : 2000). 54(1):19-28

Justice, C.M., Bishop, K., Carrington, B., Mullikin, J.C., Swindle, K., Marosy, B., Sood, R., Miller, N.H., Wilson, A.F. (2016) Evaluation of IRX Genes and Conserved Non-coding Elements in a Region on 5p13.3 Linked to Families with Familial Idiopathic Scoliosis and Kyphosis. G3 (Bethesda). 6(6):1707-12

Martinez, A.F., Abe, Y., Hong, S., Molyneux, K., Yarnell, D., Löhr, H., Driever, W., Acosta, M.T., Arcos-Burgos, M., Muenke, M. (2016) An Ultraconserved Brain-Specific Enhancer Within ADGRL3 (LPHN3) Underpins Attention-Deficit/Hyperactivity Disorder Susceptibility. Biological psychiatry. 80(12):943-954

Cooper, S.R., Emond, M.R., Duy, P.Q., Liebau, B.G., Wolman, M.A., Jontes, J.D. (2015) Protocadherins control the modular assembly of neuronal columns in the zebrafish optic tectum. The Journal of cell biology. 211:807-14

Craig, M.P., Grajevskaja, V., Liao, H.K., Balciuniene, J., Ekker, S.C., Park, J.S., Essner, J.J., Balciunas, D., Sumanas, S. (2015) Etv2 and Fli1b Function Together as Key Regulators of Vasculogenesis and Angiogenesis. Arterioscler. Thromb. Vasc. Biol.. 35(4):865-76

Gago-Rodrigues, I., Fernández-Miñán, A., Letelier, J., Naranjo, S., Tena, J.J., Gómez-Skarmeta, J.L., Martinez-Morales, J.R. (2015) Analysis of opo cis-regulatory landscape uncovers Vsx2 requirement in early eye morphogenesis. Nature communications. 6:7054

Seiler, C., Gebhart, N., Zhang, Y., Shinton, S.A., Li, Y.S., Ross, N.L., Liu, X., Li, Q., Bilbee, A.N., Varshney, G.K., LaFave, M.C., Burgess, S.M., Balciuniene, J., Balciunas, D., Hardy, R.R., Kappes, D.J., Wiest, D.L., Rhodes, J. (2015) Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish. PLoS One. 10:e0131908

Gutierrez-Triana, J., Herget, U., Lichtner, P., Castillo-Ramírez, L.A., Ryu, S. (2014) A vertebrate-conserved cis -regulatory module for targeted expression in the main hypothalamic regulatory region for the stress response. BMC Developmental Biology. 14:41

Santos, M.E., Braasch, I., Boileau, N., Meyer, B.S., Sauteur, L., Böhne, A., Belting, H.G., Affolter, M., Salzburger, W. (2014) The evolution of cichlid fish egg-spots is linked with a cis-regulatory change. Nature communications. 5:5149

Spieler, D., Kaffe, M., Knauf, F., Bessa, J., Tena, J.J., Giesert, F., Schormair, B., Tilch, E., Lee, H., Horsch, M., Czamara, D., Karbalai, N., von Toerne, C., Waldenberger, M., Gieger, C., Lichtner, P., Claussnitzer, M., Naumann, R., Müller-Myhsok, B., Torres, M., Garrett, L., Rozman, J., Klingenspor, M., Gailus-Durner, V., Fuchs, H., Hrabě de Angelis, M., Beckers, J., Holter, S.M., Meitinger, T., Hauck, S.M., Laumen, H., Wurst, W., Casares, F., Gómez-Skarmeta, J.L., Winkelmann, J. (2014) Restless legs syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon. Genome research. 24:592-603

Balciuniene, J., Nagelberg, D., Walsh, K., Camerota, D., Georlette, D., Biemar, F., Bellipanni, G., and Balciunas, D. (2013) Efficient disruption of Zebrafish genes using a Gal4-containing gene trap. BMC Genomics. 14(1):619

Hochgreb-Hägele, T., and Bronner, M.E. (2013) A novel FoxD3 gene trap line reveals neural crest precursor movement and a role for FoxD3 in their specification. Developmental Biology. 374(1):1-11

Peralta, M., Steed, E., Harlepp, S., González-Rosa, J.M., Monduc, F., Ariza-Cosano, A., Cortés, A., Rayón, T., Gómez-Skarmeta, J.L., Zapata, A., Vermot, J., and Mercader, N. (2013) Heartbeat-Driven Pericardiac Fluid Forces Contribute to Epicardium Morphogenesis. Current biology : CB. 23(18):1726-35

Regadas, I., Matos, M.R., Monteiro, F.A., Gomez-Skarmeta, J.L., Lima, D., Bessa, J., Casares, F., and Reguenga, C. (2013) Several Cis-regulatory Elements Control mRNA Stability, Translation Efficiency, and Expression Pattern of Prrxl1 (Paired Related Homeobox Protein-like 1). The Journal of biological chemistry. 288(51):36285-301

Bogdanovic, O., Fernandez-Minan, A., Tena, J.J., de Lacalle-Mustienes, E., Hidalgo, C., van Kruysbergen, I., van Heeringen, S.J., Veenstra, G.J., and Gomez-Skarmeta, J.L. (2012) Dynamics of enhancer chromatin signatures mark the transition from pluripotency to cell specification during embryogenesis. Genome research. 22(10):2043-2053

Freitas, R., Gómez-Marín, C., Wilson, J.M., Casares, F., and Gómez-Skarmeta, J.L. (2012) Hoxd13 contribution to the evolution of vertebrate appendages. Developmental Cell. 23(6):1219-1229

Irimia, M., Royo, J.L., Burguera, D., Maeso, I., Gómez-Skarmeta, J.L., and Garcia-Fernandez, J. (2012) Comparative genomics of the Hedgehog loci in chordates and the origins of Shh regulatory novelties. Scientific Reports. 2:433

Irimia, M., Tena, J.J., Alexis, M., Fernandez-Miñan, A., Maeso, I., Bogdanovic, O., de la Calle-Mustienes, E., Roy, S.W., Gómez-Skarmeta, J.L., and Fraser, H.B. (2012) Extensive conservation of ancient microsynteny across metazoans due to cis-regulatory constraints. Genome research. 22(12):2356-2367

Ni, T.T., Lu, J., Zhu, M., Maddison, L.A., Boyd, K.L., Huskey, L., Ju, B., Hesselson, D., Zhong, T.P., Page-McCaw, P.S., Stainier, D.Y., and Chen, W. (2012) Conditional control of gene function by an invertible gene trap in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 109(38):15389-15394

Royo, J.L., Bessa, J., Hidalgo, C., Fernández-Miñán, A., Tena, J.J., Roncero, Y., Gómez-Skarmeta, J.L., and Casares, F. (2012) Identification and Analysis of Conserved cis-Regulatory Regions of the MEIS1 Gene. PLoS One. 7(3):e33617

Rehn, K., Wong, K.S., Balciunas, D., and Sumanas, S. (2011) Zebrafish enhancer trap line recapitulates embryonic aquaporin 1a expression pattern in vascular endothelial cells. The International journal of developmental biology. 55(6):613-618

Royo, J.L., Hidalgo, C., Roncero, Y., Seda, M.A., Akalin, A., Lenhard, B., Casares, F., and Gómez-Skarmeta, J.L. (2011) Dissecting the transcriptional regulatory properties of human chromosome 16 highly conserved non-coding regions. PLoS One. 6(9):e24824

Tena, J.J., Alonso, M.E., de la Calle-Mustienes, E., Splinter, E., de Laat, W., Manzanares, M., and Gómez-Skarmeta, J.L. (2011) An evolutionarily conserved three-dimensional structure in the vertebrate Irx clusters facilitates enhancer sharing and coregulation. Nature communications. 2:310

Trinh, A., Hochgreb, T., Graham, M., Wu, D., Ruf-Zamojski, F., Jayasena, C.S., Saxena, A., Hawk, R., Gonzalez-Serricchio, A., Dixson, A., Chow, E., Gonzales, C., Leung, H.Y., Solomon, I., Bronner-Fraser, M., Megason, S.G., and Fraser, S.E. (2011) A versatile gene trap to visualize and interrogate the function of the vertebrate proteome. Genes & Development. 25(21):2306-20

Wong, A.C., Draper, B.W., and Van Eenennaam, A.L. (2011) FLPe functions in zebrafish embryos. Transgenic Research. 20(2):409-415

Zigman, M., Trinh, L.A., Fraser, S.E., and Moens, C.B. (2011) Zebrafish Neural Tube Morphogenesis Requires Scribble-Dependent Oriented Cell Divisions. Current biology : CB. 21(1):79-86

Bessa, J., Tena, J.J., de la Calle-Mustienes, E., Fernández-Miñán, A., Naranjo, S., Fernández, A., Montoliu, L., Akalin, A., Lenhard, B., Casares, F., and Gómez-Skarmeta, J.L. (2009) Zebrafish enhancer detection (ZED) vector: A new tool to facilitate transgenesis and the functional analysis of cis-regulatory regions in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 238(9):2409-2417

Boniface, E.J., Lu, J., Victoroff, T., Zhu, M., and Chen, W. (2009) FlEx-based transgenic reporter lines for visualization of Cre and Flp activity in live zebrafish. Genesis (New York, N.Y. : 2000). 47(7):484-491

Additional Citations (4):

Zebrafish Nomenclature Committee (2022) Nomenclature Data Curation (2022). Nomenclature Committee Submission.

Zebrafish Nomenclature Committee (2021) Nomenclature Data Curation (2021). Nomenclature Committee Submission.

Zebrafish Nomenclature Committee (2016) Nomenclature Data Curation (2016). Nomenclature Committee Submission.

Hutcheson, D., Otsuna, H., Chien, C.B., Dorsky, R. (2013) Enhancer Trap Mutants, Gal4 Project. ZFIN Direct Data Submission.