Phenotype Summary

Phenotypes

Publication	Data		Phenotype
Ye et al., 2020	Figure 6		neuromast support cell cell population proliferation increased occurrence, ameliorated
Zhang et al., 2020	Fig. 1		ependymal cell motile cilium assembly decreased occurrence, abnormal ependymal cell motile cilium assembly normal occurrence, normal spinal cord ependymal cell ab1-tuba labeling absent, abnormal spinal cord has fewer parts of type ependymal cell motile cilium, abnormal spinal cord has normal numbers of parts of type ependymal cell motile cilium, normal
Young et al., 2019	Fig. 5		optic cup neuron atoh7 expression increased amount, abnormal optic vesicle neurogenesis increased occurrence, abnormal
Roberson et al., 2017	Fig. 5		diencephalon dorsal region fgf8a expression increased distribution, abnormal
Zhai et al., 2017	Fig. 4		intestine ccnd1 expression decreased amount, abnormal intestine ccne2 expression decreased amount, abnormal intestine myca expression decreased amount, abnormal intestine decreased size, abnormal intestine size, normal liver ccnd1 expression decreased amount, abnormal liver ccne2 expression decreased amount, abnormal liver myca expression decreased amount, abnormal liver decreased size, abnormal liver size, normal pancreas ccnd1 expression decreased amount, abnormal pancreas ccne2 expression decreased amount, abnormal pancreas myca expression decreased amount, abnormal pancreas decreased size, abnormal pancreas size, normal
	Fig. 6		liver decreased size, abnormal liver increased size, abnormal pancreas decreased size, abnormal pancreas increased size, abnormal
Lin et al., 2016	Fig. 7		midbrain dorsal region lef1 expression decreased amount, abnormal midbrain dorsal region stmn4 expression decreased amount, abnormal
Venero Galanternik M. et al., 2016	Fig. 4		posterior lateral line primordium etv4 expression decreased amount, abnormal posterior lateral line primordium lef1 expression decreased amount, abnormal
Felber et al., 2015	Fig. 3		ceratobranchial 5 tooth ossification decreased occurrence, abnormal hyomandibula ossification decreased occurrence, abnormal opercle col10a1a expression decreased amount, abnormal opercle col1a2 expression decreased amount, abnormal opercle ossification decreased occurrence, abnormal ossification decreased occurrence, abnormal
	Fig. 4		opercle sp7 expression decreased amount, abnormal
	Fig. 6		opercle sp7 expression absent, abnormal pharyngeal arch 3-7 fgf3 expression decreased amount, abnormal pharyngeal arch 3-7 il17rd expression decreased amount, abnormal pharyngeal arch 3-7 spry1 expression decreased amount, abnormal pharyngeal arch 3-7 spry4 expression decreased amount, abnormal
	Fig. S3		pharyngeal arch 3-7 axin2 expression decreased amount, abnormal pharyngeal arch 3-7 wif1 expression decreased amount, abnormal
Nagendran et al., 2015	Fig. 3		embryonic medial fin morphogenesis decreased process quality, abnormal epidermal basal stratum canonical Wnt signaling pathway decreased process quality, abnormal epidermal basal stratum ecto-epithelial cell oblong, abnormal epidermal basal stratum epithelial cell morphogenesis decreased process quality, abnormal
	Fig. 5		median fin fold epithelial cell proliferation increased occurrence, abnormal
	Fig. 7		epidermal basal stratum canonical Wnt signaling pathway decreased process quality, abnormal median fin fold laminin complex decreased amount, abnormal
Venero Galanternik et al., 2015	Fig. 4		posterior lateral line primordium etv4 expression decreased distribution, abnormal posterior lateral line primordium etv4 expression spatial pattern, ameliorated posterior lateral line primordium fgf3 expression absent, abnormal posterior lateral line primordium fgf3 expression spatial pattern, ameliorated posterior lateral line primordium lef1 expression decreased distribution, abnormal posterior lateral line primordium lef1 expression spatial pattern, ameliorated
Lee et al., 2014	Fig. 6		phosphatidylinositol 3-kinase/protein kinase B signal transduction decreased process quality, abnormal Wnt signaling pathway decreased process quality, abnormal
Lancman et al., 2013	Fig. 4		hepaticobiliary system development disrupted, abnormal pancreas development disrupted, abnormal
Liu et al., 2013	Fig. 2		neuroectoderm anterior region increased size, abnormal neuroectoderm anterior region size, normal
Novikov et al., 2013	Fig. 12		canonical Wnt signaling pathway decreased process quality, abnormal cardioblast cell fate specification process quality, normal myocardial precursor physical object quality, normal
Wada et al., 2013	Fig. 4		posterior lateral line neuromast decreased amount, abnormal
Wieffer et al., 2013	Fig. 3		pectoral fin development disrupted, abnormal whole organism anterior-posterior axis decreased length, abnormal whole organism lacks parts or has fewer parts of type pectoral fin, abnormal
	Fig. S3		whole organism lacks all parts of type pectoral fin, abnormal
Shin et al., 2012	Fig. 3		liver present, normal
Wang et al., 2012	Fig. 3		cell proliferation in forebrain decreased occurrence, abnormal hypothalamus has extra parts of type neuronal stem cell, abnormal hypothalamus has extra parts of type radial glial cell, abnormal hypothalamus has fewer parts of type GABAergic neuron, abnormal hypothalamus has fewer parts of type serotonergic neuron, abnormal neural precursor cell proliferation decreased occurrence, abnormal neurogenesis disrupted, abnormal neuronal stem cell undifferentiated, abnormal
Peukert et al., 2011	Fig. 5		dorsal thalamus cellular quality, abnormal thalamus development decreased process quality, abnormal Wnt signaling pathway decreased occurrence, abnormal