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Phenotype Summary
Fish:
ml2Tg + MO1-smn1
Conditions:
All
Phenotypes
Publication
Data
Phenotype
Boyd
et al.
, 2017
Fig. 3
primary motor neuron axon decreased length, abnormal
primary motor neuron axonogenesis disrupted, abnormal
Fig. 6
primary motor neuron axon decreased length, abnormal
primary motor neuron axon length, ameliorated
primary motor neuron axon terminus swollen, abnormal
primary motor neuron axonogenesis disrupted, abnormal
primary motor neuron axonogenesis process efficacy, ameliorated
Riessland
et al.
, 2017
Fig. 3
CaP motoneuron axon decreased length, abnormal
CaP motoneuron axon extension involved in axon guidance decreased process quality, abnormal
CaP motoneuron axon increased branchiness, abnormal
CaP motoneuron collateral sprouting increased occurrence, abnormal
fast muscle cell neuromuscular junction decreased width, abnormal
fast muscle cell neuromuscular junction development decreased process quality, abnormal
fast muscle cell neuromuscular synaptic transmission decreased process quality, abnormal
fast muscle cell synaptic cleft decreased width, abnormal
whole organism
smn1
expression decreased amount, abnormal
Fig. S3
swimming decreased rate, abnormal
Hosseinibarkooie
et al.
, 2016
Fig. 8
motor neuron axon increased branchiness, abnormal
motor neuron axon truncated, abnormal
Powis
et al.
, 2016
Fig. 1
motor neuron axon branchiness, abnormal
motor neuron axon morphology, abnormal
motor neuron axon truncated, abnormal
swimming behavior process quality, abnormal
Sleigh
et al.
, 2014
Fig. 5
axonogenesis disrupted, abnormal
motor neuron axon absent, abnormal
motor neuron axon bifurcated, abnormal
motor neuron axon guidance disrupted, abnormal
motor neuron axon truncated, abnormal
motor neuron decreased amount, abnormal
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