- Title
-
Light-controllable dithienylethene-modified cyclic peptides: photoswitching the in vivo toxicity in zebrafish embryos
- Authors
- Afonin, S., Babii, O., Reuter, A., Middel, V., Takamiya, M., Strähle, U., Komarov, I.V., Ulrich, A.S.
- Source
- Full text @ Beilstein J Org Chem
DAE photoswitch and photoswitchable peptides explored in this study. (A) The reversible photoisomerization of the dithienylethene photoswitch core. (B) Photoconversion between ring-open and ring-closed photoforms of DAE-derived peptides. (C) Structures of the non-photoswitchable cytotoxic peptide GS ( |
Two versions of the |
The in vivo toxicity against |
|
Phototherapeutic cytotoxic action against HeLa cells of GS |