| ZFIN ID: ZDB-EXP-201022-21 |
Experiment Conditions Description: high cholesterol, chemical treatment by environment: alvespimycin
| high cholesterol |
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| Name: | high cholesterol |
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| Synonyms: | |
| Definition: | Cholesterol content condition in which the amount of cholesterol in the diet is elevated. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000119] |
| chemical treatment by environment: alvespimycin |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | alvespimycin |
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| Synonyms: | (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-{[2-(dimethylamino)ethyl]amino}-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate, 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin, 17-DMAG |
| Definition: | A 19-membered macrocyle that is geldanamycin in which the methoxy group attached to the benzoquinone moiety has been replaced by a 2-(N,N-dimethylamino)ethylamino group. |
| Ontology: | ChEBI [CHEBI:65324] ( EBI ) |
| Publication: | Gungor et al., 2019 |
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