ZFIN ID: ZDB-EXP-200716-7 |
Experiment Conditions Description: chemical treatment by environment: tyrphostin AG 1478, chemical treatment by environment: N-phenylthiourea, chemical treatment by environment: picrotoxin
chemical treatment by environment: tyrphostin AG 1478 |
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Name: | chemical treatment by environment |
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Synonyms: | |
Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
Name: | tyrphostin AG 1478 |
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Synonyms: | AG 1478, AG-1478, N-(3-chlorophenyl)-6,7-dimethoxy-quinazolin-4-amine, tyrphostin AG-1478 |
Definition: | A member of the class of quinazolines that is quinazoline substituted by methoxy groups at positions 6 and 7 and a (3-chlorophenyl)nitrilo group at position 4. It acts as an epidermal growth factor receptor antagonist. |
Ontology: | ChEBI [CHEBI:75404] ( EBI ) |
chemical treatment by environment: N-phenylthiourea |
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Name: | chemical treatment by environment |
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Synonyms: | |
Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
Name: | N-phenylthiourea |
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Synonyms: | 1-phenyl-2-thiourea, 1-phenylthiourea, alpha-phenylthiourea, monophenyl thiourea, phenyl-2-thiourea, phenylthiocarbamide, phenylthiourea, PhNHC(=S)NH2, PhNHC(S)NH2, PhNHCSNH2, PTC, PTU |
Definition: | A member of the class of thioureas that is thiourea in which one of the hydrogens is replaced by a phenyl group. Depending on their genetic makeup, humans find it either very bitter-tasting or tasteless. This unusual property resulted in N-phenylthiourea being used in paternity testing prior to the advent of DNA testing. |
Ontology: | ChEBI [CHEBI:46261] ( EBI ) |
chemical treatment by environment: picrotoxin |
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Name: | chemical treatment by environment |
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Synonyms: | |
Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
Name: | picrotoxin |
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Synonyms: | (1R,3R,5S,8S,9R,12S,13R,14R)-1-hydroxy-13-methyl-14-(prop-1-en-2-yl)-4,7,10-trioxapentacyclo[6.4.1.1(9,12).0(3,5).0(5,13)]tetradecane-6,11-dione -- (1R,3R,5S,8S,9R,12S,13R,14S)-1-hydroxy-14-(2-hydroxypropan-2-yl)-13-methyl-4,7,10-trioxapentacyclo[6.4.1.1(, Cocculin, Cocculus, Coques du levant, picrotoxine, picrotoxinin - picrotin (1:1) |
Definition: | A mixture consisting of equimolar amounts of picrotoxinin and picrotin found in the climbing plant Anamirta cocculus. |
Ontology: | ChEBI [CHEBI:134126] ( EBI ) |
Publication: | Allen et al., 2019 |
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