| ZFIN ID: ZDB-EXP-200514-1 |
Experiment Conditions Description: amputation: caudal fin, chemical treatment: plerixafor
| amputation: caudal fin |
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| Name: | amputation |
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| Synonyms: | |
| Definition: | Resection condtion in which all or part of an extremity such as the fin or tail are removed. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000172] |
| Name: | caudal fin |
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| Synonyms: | tail, tail fin |
| Definition: | Fin that is the most posterior median fin. It is composed of a complex of three modified centra and modified neural and hemal arches and spines. |
| Ontology: | Anatomy Ontology [ZFA:0001058] |
| chemical treatment: plerixafor |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | plerixafor |
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| Synonyms: | 1,1'-(benzene-1,4-diyldimethanediyl)bis(1,4,8,11-tetraazacyclotetradecane), 1,1'-[1,4-phenylenebis(methylene)]bis(1,4,8,11-tetraazacyclotetradecane), 1-[[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane, AMD 3100, AMD-3100, AMD3100, JKL 169, JM3100, Mozobil, plerixafor, plerixaforum, SDZ SID 791 |
| Definition: | An azamacrocycle consisting of two cyclam rings connected by a 1,4-phenylenebis(methylene) linker. It is a CXCR4 chemokine receptor antagonist and a hematopoietic stem cell mobilizer. It is used in combination with grulocyte-colony stimulating factor (G-CSF) to mobilize hematopoietic stem cells to the perpheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin's lymphoma and multiple myeloma. |
| Ontology: | ChEBI [CHEBI:125354] ( EBI ) |
| Publication: | Isles et al., 2019 |
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