ZFIN ID: ZDB-EXP-200514-1
Experiment Conditions Description: amputation: caudal fin, chemical treatment: plerixafor
amputation: caudal fin
Name: amputation
Definition: Resection condtion in which all or part of an extremity such as the fin or tail are removed.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000172]
Name: caudal fin
Synonyms: tail, tail fin
Definition: Fin that is the most posterior median fin. It is composed of a complex of three modified centra and modified neural and hemal arches and spines.
Ontology: Anatomy Ontology [ZFA:0001058]
chemical treatment: plerixafor
Name: chemical treatment
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: plerixafor
Synonyms: 1,1'-(benzene-1,4-diyldimethanediyl)bis(1,4,8,11-tetraazacyclotetradecane), 1,1'-[1,4-phenylenebis(methylene)]bis(1,4,8,11-tetraazacyclotetradecane), 1-[[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane, AMD 3100, AMD-3100, AMD3100, JKL 169, JM3100, Mozobil, plerixafor, plerixaforum, SDZ SID 791
Definition: An azamacrocycle consisting of two cyclam rings connected by a 1,4-phenylenebis(methylene) linker. It is a CXCR4 chemokine receptor antagonist and a hematopoietic stem cell mobilizer. It is used in combination with grulocyte-colony stimulating factor (G-CSF) to mobilize hematopoietic stem cells to the perpheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin's lymphoma and multiple myeloma.
Ontology: Chebi [CHEBI:125354]
Publication: Isles et al., 2019