| ZFIN ID: ZDB-EXP-190218-6 |
Experiment Conditions Description: chemical treatment by environment: fluoxetine, chemical treatment by environment: NMDA receptor antagonist
| chemical treatment by environment: fluoxetine |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | fluoxetine |
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| Synonyms: | (+-)-N-methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-p-tolyl)oxy)propylamine, (+-)-N-methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine, fluoxetina, fluoxetine, fluoxetinum, Prozac, rac-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine |
| Definition: | A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder. |
| Ontology: | ChEBI [CHEBI:5118] ( EBI ) |
| chemical treatment by environment: NMDA receptor antagonist |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | NMDA receptor antagonist |
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| Synonyms: | N-methyl-D-aspartate receptor antagonist, N-methyl-D-aspartate receptor antagonists, NMDA receptor antagonists, NMDAR antagonist, NMDAR antagonists |
| Definition: | Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs. |
| Ontology: | ChEBI [CHEBI:60643] ( EBI ) |
| Publication: | Gao et al., 2018 |
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