ZFIN ID: ZDB-EXP-170524-9
Experiment Conditions Description: chemical treatment by diet: lomitapide, high fat
chemical treatment by diet: lomitapide
Name: chemical treatment by diet
Definition: Chemical treatment condition in which the chemical is introduced through the diet.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000239]
Name: lomitapide
Synonyms: AEGR 733, AEGR 773, AEGR-773, AEGR733, AEGR773, BMS 201038, BMS201038, Lojuxta, lomitapida, lomitapide, lomitapidum, N-(2,2,2-trifluoroethyl)-9-{4-[4-({[4'-(trifluoromethyl)biphenyl-2-yl]carbonyl}amino)piperidin-1-yl]butyl}-9H-fluorene-9-carboxamide
Definition: A member of the class of benzamides obtained by formal condensation of the carboxy group of 4'-(trifluoromethyl)biphenyl-2-carboxylic acid with the primary amino group of 9-[4-(4-aminopiperidin-1-yl)butyl]-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide. Used (as its mesylate salt) as a complement to a low-fat diet and other lipid-lowering treatments in patients with homozygous familial hypercholesterolemia.
Ontology: Chebi [CHEBI:72297]
high fat
Name: high fat
Definition: Fat content condition in which the amount of fat in the diet is elevated.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000122]
Publication: Zeituni et al., 2016