ZFIN ID: ZDB-EXP-150518-3
Experiment Conditions Description: amputation: caudal fin, chemical treatment: BGJ-398
amputation: caudal fin
Name: amputation
Synonyms:
Definition: Resection condtion in which all or part of an extremity such as the fin or tail are removed.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000172]
Name: caudal fin
Synonyms: tail, tail fin
Definition: Fin that is the most posterior median fin. It is composed of a complex of three modified centra and modified neural and hemal arches and spines.
Ontology: Anatomy Ontology [ZFA:0001058]
chemical treatment: BGJ-398
Name: chemical treatment
Synonyms:
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: BGJ-398
Synonyms: 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-{[4-(4-ethylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)-1-methylurea, BGJ398, NVP-BGJ398
Definition: A member of the class of phenylureas that is urea in which a hydrogen attached to one of the nitrogens is replaced by a 2,6-dichloro-3,5-dimethoxyphenyl group, while the hydrogens attached to the other nitrogen are replaced by a methyl group and a 6-{[4-(4-ethylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl group. It is a potent and selective fibroblast growth factor receptor inhibitor.
Ontology: ChEBI [CHEBI:63451]  ( EBI )
Publication: De Smet et al., 2014