FIGURE

Figure 7

ID

ZDB-FIG-250329-70

Publication

Cho et al., 2025 - Synergistic Efficacy of Policosanol (Raydel^®) and Banaba Leaf Extract to Treat Hyperglycemia and Dyslipidemia in Streptozotocin-Induced Diabetic and Hyperlipidemic Zebrafish (Danio rerio): Protection of Liver and Kidney with Enhanced Tissue Regeneration

Other Figures

All Figure Page

Back to All Figure Page

Figure 7

Effect of banaba leaf extract and policosanol (alone or in combination) on the reactive oxygen species (ROS), apoptosis, and senescence in the liver of the streptozotocin-treated hyperlipidemic zebrafish (n = 3). (A,B) dihydroethidium (DHE) and acridine orange (AO) fluorescent staining to determine ROS and apoptosis, respectively. (C) Senescence-associated β-galactosidase (SA-β-gal) staining. (D,E) Quantification of DHE and AO fluorescence intensity. (F) Percentage quantification of the SA-β-gal-positive area. Abbreviations: HCD (high cholesterol diet), STZ (streptozotocin), BNB (banaba), and PCO (policosanol). The symbol *** underlines the statistical significance at p < 0.001 vs. the HCD+STZ group. † and †† indicate statistical significance at p < 0.05 and p < 0.01 vs. the BNB+PCO group.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Pharmaceuticals (Basel)