Postdoctoral Position. (University of Iowa) . Posted 08 May 2008
Postdoctoral Position. (University of Zurich) . Posted 08 May 2008
Zebrafish Facility Director. (Children's Hospital, Boston) . Posted 08 May 2008
Postdoctoral Position. (New York University) . Posted 05 May 2008
Aquatics/Laboratory Technician. (National Institutes of Health) . Posted 02 May 2008
Research Technician . (University of Birmingham) . Posted 28 April 2008
Research Technician. (Johns Hopkins University) . Posted 24 April 2008
Postdoctoral Position. (Sanofi-aventis - Toulouse, France) . Posted 23 April 2008
Postdoctoral Position. (Zebrafish Group - Campus IFOM-IEO Milan, Italy) . Posted 21 April 2008
Postdoctoral Position. (University of California, Irvine) . Posted 16 April 2008
Graduate Research Assistantship in Gene Banking of Aquarium Fish Models. (Louisiana State University) . Posted 14 April 2008
Project Leader, Drug Discovery. (Znomics Inc.) . Posted 14 April 2008
Research Assistant/Associate, Drug Discovery. (Znomics Inc.) . Posted 14 April 2008
Post-Doctoral Position. (University of Massachusetts Medical School) . Posted 14 April 2008
Post-Doctoral Position. (Fox Chase Cancer Center) . Posted 14 April 2008
Post-Doctoral Position. (Fox Chase Cancer Center) . Posted 14 April 2008
Post-Doctoral Position. (Fox Chase Cancer Center) . Posted 14 April 2008
Three Group Leader Positions. (Center for Genomic Regulation, Barcelona) . Posted 31 March 2008
Zebrafish Cardiovascular Biologist. (Victor Chang Cardiac Research Institute) . Posted 31 March 2008
Research Technicians. (National Institute for Medical Research) . Posted 31 March 2008
Post-Doctoral Position. (University of Michigan Medical Center) . Posted 26 March 2008
Senior Research Technologist . (St. Jude Children's Research Hospital, Memphis, Tennessee) . Posted 21 March 2008
Senior Research Assistant . (University of Oregon Institute of Neuroscience ) . Posted 21 March 2008
Research Assistant/Lab Manager. (University of Oregon Institute of Neuroscience ) . Posted 21 March 2008
Zebrafish facility manager position. (Duke University) . Posted 18 March 2008
Faculty Position in Human Genetics. (Rutgers University) . Posted 18 March 2008
Senior Scientist (Zebrafish Toxicology) . (Summit plc ) . Posted 18 March 2008
Postdoctoral Position. (National Institute of Child Health and Human Development) . Posted 27 February 2008
Research Assistant. (College of Natural Sciences, Forestry and Agriculture, University of Maine) . Posted 25 February 2008
Postdoctoral Position. (Northwestern University, Feinberg School of Medicine, Chicago) . Posted 25 February 2008
Postdoctoral Fellowship. (National Institute for Medical Research, London) . Posted 15 February 2008
Technician. (Centre for Genomic Regulation in Barcelona, Spain) . Posted 07 February 2008
Assistant Professor. (SUNY Brockport) . Posted 01 February 2008
Postdoctoral Position. (Mayo Clinic College of Medicine) . Posted 01 February 2008
Postdoctoral Position. (Medical College of Wisconsin, Milwauke WI) . Posted 29 January 2008
Postdoctoral Position. (Medical College of Wisconsin, Milwauke WI) . Posted 29 January 2008
Research Technician. (The Netherlands Cancer Institute) . Posted 28 January 2008
Postdoctoral Position. (University of California San Francisco (UCSF)) . Posted 28 January 2008
Postdoctoral Research Scientists. (Max-Planck Institute for Molecular Biomedicine, Muenster, Germany) . Posted 22 January 2008
Postdoctoral and PhD position. (Max Planck Institute, Heidelberg, Germany) . Posted 18 January 2008
Postdoctoral Position. (Cincinnati Children's Hospital Medical Center) . Posted 17 January 2008
Postdoctoral Position. (Sanofi-Aventis, Toulouse, France) . Posted 08 January 2008
Project Director. (Biobide, San Sebastian, Spain 2009) . Posted 07 January 2008
Two Post-Doctoral Positions. (MRC Laboratory of Molecular Biology, Cambridge) . Posted 02 January 2008
Graduate Student/PDF Position. (University of Calgary, Alberta) . Posted 19 December 2007
Post Doctoral position. (University of Leuven, Belgium) . Posted 19 December 2007
Applications are invited for postdoctoral positions in the laboratory of Dr. Fang Lin in the Department of Anatomy and Cell Biology, University of Iowa, with an expected start date of September 2008. The laboratory is interested in studying G protein couple receptors and G protein signaling in zebrafish embryogenesis. These studies will employ a combination of genetic, genomic, cellular, and biochemical techniques. A highly motivated Ph.D. with experience in the study of signal transduction, developmental and molecular biology is desired. Previous experience with the zebrafish model is preferable, but not a requirement, as training will be provided.
Iowa City is a very nice, safe and collegial town with high living standards, but inexpensive cost of living as compared to larger cities. Recent survey ranks UI as top University for postdoctoral students
(http://www.news-releases.uiowa.edu/2007/March/030107post-doctorate.html) To apply, please send a CV, statement of research interests, and name & contact details of three referees to:
Dr. Fang Lin
Email: fang.lin@vanderbilt.edu
A Post-doctoral position is available to study visual system development and function in the zebrafish. We combine molecular genetic, behavioral and physiological approaches to study visual system function (http://www.zool.uzh.ch/Research/Neurobiology/Neuhauss_en.html).
Interested postdoctoral candidates must have a deep interest in the retina and the visual system, including visually mediated behavior.
Expertise in modern microscopy, a solid background in molecular biology, and practical experience with the zebrafish system is desirable.
Applicants should be self-motivated, creative, communicative, and willing to work in a young student dominated team. Zurich with its two major research universities (University of Zurich and Swiss Federal Institute of Technology) is a vibrant international research hub. It provides state of the art research facilites and a training environment with an international group of faculty and trainees.
Salary support is available through an institute's position, however, candidates are encouraged to apply for their own fellowship. Send CV including list of publications and names of references to:
Prof. Stephan Neuhauss
Professur fur Neurobiologie
Institute of Zoology
University of Zurich
Winterthurerstrasse 190
CH - 8057 Zurich
Switzerland
stephan.neuhauss@zool.uzh.ch
Director of the Zebrafish Facility at Children's Hospital Boston
The laboratory utilizes zebrafish as a genetic model system to understand blood disorders and cancer. The successful applicant will supervise 20 post-doctoral fellows or graduate students in the care of zebrafish mutants. The director may also be involved in bench science. PhD's are welcome to apply, but only BS or BA required.
Please send three recommendation letters and CV to:
Dr. Leonard Zon
Howard Hughes Medical Institute/Children's Hospital Boston
300 Longwood Ave, Karp 7
Boston, MA 02115
giarla@enders.tch.harvard.edu
Fax: 617-730-0222
A postdoctoral position to study brain angiogenesis in the zebrafish and with AHA funding is available immediately in the Torres-Vazquez lab (http://saturn.med.nyu.edu/research/dg/torreslab/) at NYU's Kimmel Center for Biology and Medicine of the Skirball Institute for Biomolecular Medicine (Developmental Genetics Program). The overall goal of our lab is to understand the genetic programs that regulate the endothelial cell behaviors that assemble the vasculature.
The project is focused on the cloning and phenotypic characterization of 'no food for thought', a zebrafish mutant with a brain-specific deficit in angiogenesis. This project is a terrific opportunity for the candidate to build a career in an area of great biomedical relevance and in a superb intellectual environment.
Additional areas of interest in the lab include the role of Sema-PlxnD1 signaling in vascular patterning (see Dev Cell. 2004 7(1): 117-23) and the establishment of novel tools for studying vascular development in vivo. Applicants must have a Ph.D. in a biological science, be able to think and work independently, be self-motivated and have both a solid publication record and molecular biology experience. Practical experience in genetics, developmental biology, confocal imaging, cell biology and/or biochemistry is a plus. Experience with zebrafish is not required. Mastery of the English language is essential.
To apply please send an e-mail to Dr. Jesus Torres-Vazquez at torres@saturn.med.nyu.edu with the subject line "Postdoctoral application" followed by your name and include a single attachment (word document or PDF file) containing:
One-page cover letter describing scientific accomplishments, research goals and expected date of availability
Complete CV with bibliography
Name, e-mail, telephone number address for 3 references (one should be your Ph.D. thesis advisor)
Applicants accepted for initial consideration will be subsequently contacted for letters of reference.
An aquatics/laboratory technician is sought for a zebrafish research laboratory at the National Institute of Child Health and Human Development, NIH. The successful applicant will assist researchers studying the embryogenesis of the circulatory system in this model vertebrate.
Qualifications:
B.S. in the Life Sciences is required. Previous aquatics and/or fish husbandry experience and/or education preferred. Previous laboratory experience desirable, particularly in molecular biology. Previous experience with genetic mapping a plus.
Description:
Provide general husbandry and management support for a zebrafish research colony as well as more specialized support such as in vitro fertilization, fin clipping, and microinjection of zebrafish eggs. Additional duties will include some laboratory bench work such as bacterial culture and transformation, DNA purification, PCR, gel electrophoresis, RNA extraction, reverse transcription, in situ hybridization, antibody staining, SDS-page gel running, and Western blotting.
To apply email a cover letter and full resume with names and contact information for three references to Brant Weinstein at flyingfish2@nih.gov.
Must be a US Citizen or currently hold authorization to work in the US.
REPRODUCTIVE AND CHILD HEALTH
Research Technician
Applications are sought for a Research Technician to work in a project to develop a zebrafish model for Birt Hogg Dube (BHD) syndrome. Research is focused on understanding the function of the folliculin and other candidate genes involved in BHD. You will use embryological, molecular, genetic and pharmacological methods to execute experiments. You should have a BTech Higher or equivalent experience in a biological subject and experience of molecular and cell biology techniques, zebrafish embryo genetics technique.
Informal enquiries can be addressed to Dr F Mueller on email: f.muller@bham.ac.uk
Starting salary £18,534 - £21,747 a year (potential progression on performance once in post to £23,057). Pay award pending with effect from 1 May 2008. From 1 April 2008 staff will be eligible to join the University's new defined contribution pension scheme. Existing staff may continue to receive their current benefits. The post is available for a period of 12 months.
Closing date: 19 May 2008
Reference: M46261
Details from:
0121 415 9000
http://www.hr.bham.ac.uk/jobs
HR, University of Birmingham
Edgbaston
Birmingham
B15 2TT
A University of Fairness and Diversity
We are seeking an enthusiastic, motivated individual who can work independently, to join our research group using zebrafish as a model system. Your primary responsibility will be to maintain our 500+ tank zebrafish facility here at Johns Hopkins. This would include feeding, routine maintenance of water system, , collecting embryos, identifying mutation carriers, and maintaining the computer database for the facility. It is imperative that you keep accurate records to insure our facility's compliance with animal care regulations. You will also have an opportunity to learn more specialized techniques, such as micro-manipulations of zebrafish embryos, whole mount in situ hybridization, and photomicroscopy. Above all, we seek a reliable, organized employee, who can work independently, can keep careful and complete records, and is excited about acquiring new skills. Please apply to Dr. Michael Parsons (mparson3@jhmi.edu) and Senecca Bessling (slbessling@jhmi.edu).
Mike Parsons, Ph.D.
Johns Hopkins University
Department of Surgery
733 N. Broadway, BRB 469
Baltimore, MD 21205
Phone: (410) 502-2982
Fax: (410) 502-1853
Sanofi-aventis is devoted to the treatment and prevention of diseases through the research and development of innovating pharmaceuticals and human vaccines concerning 7 major therapeutic areas: cardiovascular, thrombosis, central nervous system, oncology, metabolic disorders, internal medicine and vaccines. Our group is present in more than 100 countries and over the 5 continents. http://www.sanofi-aventis.com
One postdoctoral position is available in the Exploratory Department / Biochemistry at the research center of Toulouse. The candidate will design and implement new experimental models intended for the identification of anti-tuberculous drugs and for the understanding of their mode of action, based on the Zebrafish/Mycobacterium marinum infection model.
The successful candidate must have a Ph.D. Experience in the manipulation of Zebrafish and experience in microscopy techniques such as DIC (Differential Interference Contrast) and/or DCC (Confocal microscopy) is required. Background knowledge in microbiology will be appreciated as well.
Fluent in English
French appreciated
18 months fixed-term contract
Starting date: Between July and September 2008
Please send e-mail application including detailed CV to: Astrid.Rey@Sanofi-Aventis.com
Belen.Barrio-Perez@Sanofi-Aventis.com
The Zebrafish Group invites applications for a postdoctoral candidate with a strong interest and solid background in vascular biology. Previous experience with the zebrafish model is preferable, but not a requirement, as training will be provided.
One of the main projects of the lab is the study of tumor angiogenesis using our cancer prone transgenic lines and transplantation techniques. The successful candidate will develop assays to study and manipulate the development of tumor vessels and metastatic migration in vivo. A range of techniques, including confocal microscopy of live zebrafish and 4D analysis will be used in the project.
Requirements:
MD or PhD in biological subjects. Expertise in vascular biology using both in vivo and in vitro approaches is highly desirable. We are looking for a highly motivated scientist who wants to broaden her/his expertise in the vascular field with an innovative approach in the zebrafish model. A record of independent research, the ability to work in a team and a strong interest for live imaging are important requisites.
How to apply:
For preliminary inquiries please contact: Marina Mione at marina.mione@ifom-ieo-campus.it,
Web: http://www.ifom-ieo-campus.it/research/mione.php
A postdoctoral position is available to apply both experimental and computational approaches to early axis formation in zebrafish. This position will provide a unique opportunity to develop a model for anterior-posterior patterning as part of an ongoing collaborative effort between the laboratories of Drs. Thomas Schilling, Arthur Lander and Qing Nie. This effort will include the creation of transgenic reporter lines of fish to monitor signaling, together with computational modeling of the results. This will afford the successful applicant with the opportunity to generate and evaluate signaling networks at a systems level. The models developed in the context of these studies will be used to address questions of interest relating to anterior-posterior patterning of the hindbrain and neural crest. Particular emphasis will be on the retinoic acid, Fgf and Wnt signaling pathways. For more information, see the following publication, or go to http://devcell.bio.uci.edu/tschilling/.
White RJ, Nie Q, Lander AD and Schilling TF (2007). Complex regulation of cyp26a1 creates a robust retinoic acid gradient in the zebrafish embryo. PLoS Biol 5:e304.
Applicants must be highly motivated and technically experienced with strong publication records. The ideal candidate should have experience with developmental model systems and molecular biology. Prior experience with zebrafish is not required.
Please send or email a CV and reprints of relevant publications to the contact information below.
Thomas F. Schilling, PhD
Associate Professor
Department of Developmental and Cell Biology
University of California, Irvine
Natural Sciences II Building, Room 4109
Irvine, CA 92697-2300
Email: tschilli@uci.edu
Website: http://devcell.bio.uci.edu/tschilling/
Qualifications:
Applicants should have an interest in research on sperm cry preservation, reproduction, and related physiology, also a background of 1-2 years of working experience with aquarium fish including zebrafish, medaka or Xiphophorus fishes. Experience with artificial fertilization, flow cytometry, cell culture, experimental design, and statistical analyses are desirable. Candidates for the PhD scholarship must have a Master's degree, and for the MS scholarship must have a BS degree in biological sciences, animal sciences, cell biology, genetics, or related field. The graduate scholarship is for 3 years (based on existing NIH funding).
Description:
Gamete cryopreservation can benefit recovery of endangered species, maintenance of broodstocks for selective breeding, and establishment of repositories of genetic materials. The project focuses on sperm cryopreservation of research model fishes, including zebrafish, medaka, and Xiphophorus, which are characterized by small body size (2-5 cm) and limited sperm volume. Responsibilities include: 1) independent research on development of protocols for sperm cryopreservation, artificial insemination, high-throughput protocol development, and related physiological analyses, and 2) preparation of reports, manuscripts, and presentations associated with the research.
Salary: 19,500 - 20,000 US$/year with tuition waived.
Application:
Send an application letter, curriculum vitae, university transcripts, and a list of three references to:
Dr. Huiping Yang or Dr. Terrence R. Tiersch
2410 Ben Hur Road
Baton Rouge
LA 70820
Email: hyang@agcenter.lsu.edu
Phone: 225-765-2848
Application deadline: until a suitable candidate is found
Znomics Inc. has a full-time position available in the Drug Discovery department for a Project Leader in our Portland, OR location. We are searching for a Ph.D.-level scientist to lead disease modeling, drug target, and drug discovery programs. Preference will be given to candidates with experience in zebrafish, HT screening and expertise in inflammation, metabolic diseases or cancer. Ideal candidates will be able to demonstrate a history of innovative research.
Duties and Responsibilities:
Scientific management of a Drug Discovery program
Perform data analysis and contribute to the development of new programs
Address the technological requirements of HT screening
Contribute to solution of complex biological and technical challenges
Manage a team focused on medium to high throughput screening development
Manage the transfer of screening assays to screening group
Education and Experience Qualifications:
Ph.D. in the life sciences, with a minimum of 2 years experience
A good understanding of assay development, nucleic acid and protein manipulation, cell and developmental biology, genetics and genomics
Knowledgeable in compound management
Strong data analysis skills and statistical experience preferred
Excellent communication, problem-solving, and management skills
The abilities to prioritize work efforts and multi-task are essential.
Industry/Biotechnology experience a plus
How to Apply:
Email your resume to careers@znomics.com, including the code DDPL48.
To be considered, applicants must have authorization to work in the United States.
Corporate Overview:
Znomics is an innovative biotechnology company focused on drug discovery and development and engaged in research based on technology leveraging the advantageous characteristics of the zebrafish as a laboratory animal model of human diseases.
Znomics, Inc. offers a competitive salary and benefits.
Affirmative Action/Equal Opportunity Employer
Research Assistant/Associate, Drug Discovery
Znomics Inc. has a full-time position available in Drug Discovery for a Research Assistant/Associate in our Portland, OR location. We are searching for a highly motivated scientist with a B.S. or M.S. to be part of an exciting research team at a rapidly growing biotechnology company. Preference will be given to candidates with prior research experience.
Duties and Responsibilities:
Scientific support to the achievement of Drug Discovery project milestones
Perform laboratory experiments, developing drug screening assays
Perform medium to high throughput drug screening
Perform data analysis
Perform laboratory housekeeping and animal husbandry tasks
Work independently and as part of an interdisciplinary team
Education and Experience Qualifications:
B.S./M.S. in the life sciences, with 1-3 year experience in laboratory setting
Data analysis skills preferred
Excellent organizational skills and oral and written communication skills
Excellent team player
Willing to take on new techniques
Working knowledge of software tools
Industry/Biotechnology and/or zebrafish experience a plus
How to Apply:
Email your resume to careers@znomics.com, including the code DDRA38.
To be considered, applicants must have authorization to work in the United States.
Corporate Overview: Znomics is an innovative biotechnology company focused on drug discovery and development and engaged in research based on technology leveraging the advantageous characteristics of the zebrafish as a laboratory animal model of human diseases.
Znomics, Inc. offers a competitive salary and benefits.
Affirmative Action/Equal Opportunity Employer
Postdoctoral position
University of Massachusetts Medical School - Program in Gene Function & Expression
Generation of novel zebrafish knock-out and knock-in models for the study of angiogenesis.
A postdoctoral position is available to apply zinc finger nuclease (ZFN) technology to generate zebrafish knock-out and knock-in models related to blood vessel development. This position will provide a unique opportunity to exploit and further develop ZFN technology in zebrafish as part of an ongoing collaborative effort between the neighboring laboratories of Drs. Nathan Lawson and Scot Wolfe. This effort will include the application of ZFNs to generate knock-in and conditional alleles and will afford the successful applicant with the opportunity to master selection systems used to generate and evaluate site-specific ZFNs. The genetic models developed in the context of these studies will be used to address questions of interest relating to endothelial cell differentiation and angiogenesis. Particular emphasis will be on the Vegf and Notch signaling pathways, as well as development of zebrafish models for congenital vascular disease. For more information, see the following publications, or go to lawsonlab.umassmed.edu or labs.umassmed.edu/WolfeLab/index.html.
Meng, Noyes, Zhu, Lawson and Wolfe. (2008) Targeted gene inactivation in zebrafish using zinc finger nucleases, Nat. Biotech., in press.
Siekmann and Lawson (2007) Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries. Nature 445:781-784
Siekmann, Covassin, and Lawson (2008). Modulation of VEGF signalling output by the Notch pathway. Bioessays 30:303-313
Applicants must be highly motivated and technically accomplished as documented by exceptional publication record. The ideal candidate will have demonstrated experience with vertebrate developmental model systems and a strong background in molecular biology. Prior experience with zebrafish is beneficial, but not required.
Please send or email CV and reprints of relevant publications to the contact information below. Applicants accepted for initial consideration will be subsequently contacted for letters of reference.
Nathan D. Lawson, PhD
Associate Professor
Program in Gene Function and Expression
University of Massachusetts Medical School
Lazare Research Building, Room 617
364 Plantation Street
Worcester, MA 01605
e-mail: nathan.lawson@umassmed.edu
web site: http://lawsonlab.umassmed.edu
POSTDOCTORAL POSITION available July 1, 2008 to study the molecular mechanisms of T lineage development and transformation using both zebrafish and murine models. Available projects include: 1) executing a zebrafish genetic screen to identify genes controlling T cell development and transformation; 2) understanding the basis for blockade of T cell development by ribosomal protein L22 deficiency (Immunity 26:759-772, 2007); or 3) investigating the role of signal strength in αβ/γδ lineage commitment (Immunity 22: 595-606, 2005). Experience in molecular biology and zebrafish genetics desirable but not essential. The successful applicant will enjoy a competitive salary and have access to subsidized housing and childcare, and an active postdoctoral association. CV and 3 references should be sent to:
David L. Wiest, Ph.D.
Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111-2497
Fax: 215-728-2412
Email: David.Wiest@FCCC.edu
POSTDOCTORAL POSITION available July 1, 2008 to study the molecular mechanisms of B lineage development and transformation using both zebrafish and murine models. Available projects include: 1) executing a zebrafish genetic screen to identify genes controlling B cell development and transformation; 2) understanding the signals regulating the earliest stages of B cell development (J. Exp. Med. 203: 675-687, 2006); or 3) investigating the role of BCR signal strength in B cell subset determination and transformation (Immunity 23, 297-308, 2005; PNAS 99: 6955-6960, 2002). Experience in molecular biology and zebrafish genetics desirable but not essential. The successful applicant will enjoy a competitive salary and have access to subsidized housing and childcare, and an active postdoctoral association. CV and 3 references should be sent to:
Richard R. Hardy, Ph.D.
Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111-2497
Fax: 215-728-2412
Email: rr_hardy@fccc.edu
POSTDOCTORAL POSITION available July 1, 2008 to study the molecular mechanisms of T lymphocyte development using both mouse and zebrafish models. Available projects include: 1) elucidating the transcriptional control of CD4/CD8 lineage commitment in mice (Nature, 433, 826, 2005; Immunity, 28, 346, 2008); 2) identifying novel regulators of T lineage commitment through a genetic screen in zebrafish; 3) mapping a novel mouse mutation involved in T cell development and lymphomagenesis. Experience in transcriptional regulation and/or zebrafish genetics desirable but not essential. The successful applicant will enjoy a competitive salary and have access to subsidized housing and childcare, and an active postdoctoral association. CV and 3 references should be sent to:
Dietmar Kappes
Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111-2497
Fax: 215-728-2412
Email: dj_kappes@fccc.edu
The Center for Genomic Regulation (CRG, http://www.crg.es/) is a leading genomics research institute, associated with the University Pompeu Fabra (UPF) and located at the Parc de Recerca Biomedica de Barcelona (PRBB, http://www.prbb.org/). The CRG contains six research programmes: Gene Regulation, Differentiation and Cancer, Cell & Development Biology, Systems Biology, Genes and Disease and Bioinformatics & Genomics, and has a partnership with the EMBL through the Systems Biology programme. The PRBB includes three other institutions devoted to biomedical research: the Department of Life and Health Sciences of the UPF (CEXS/UPF, http://www.upf.edu/cexs/), the Municipal Institute of Medical Research (IMIM, http://www.imim.es/) and the Centre for Regenerative Medicine of Barcelona (CMRB, http://www.cmrbarcelona.org/). To give support to this scientific community the CRG has built state of the art Genomics and Light microscopy facilities, as well as Screening and FACS facilities. New developments contemplate a top of the art proteomics facility. The CRG recruits academic staff and faculty internationally and encourages mobility and exchange.
Three Group Leader positions in several Programmes
The Group Leader positions come with an initial contract for 5 years, renewable for 4 additional years upon review by an external scientific committee. Funds are provided for a Postdoctoral position, a Technician and a Graduate Student, an equipped laboratory for up to 7 people, a start-up package, as well as funding for consumables and special equipment. We have openings in the following programmes:
Gene Regulation Programme - Ref. GR-GL 0308
This programme is coordinated by M. Beato and encompasses two senior groups (J. Valcarcel and R. Shiekhattar) and three group leaders (R. Mendez, F. Gebauer and J. Vilardell) that work on various aspects of transcriptional and post-transcriptional gene regulation. Additionally CRG is also implementing a transversal project on "Cell Reprogramming". We are looking for a new group leader working in any field of gene regulation that will complement the existing groups. The candidate should have an excellent scientific record, be prepared to lead an ambitious independent group and to collaborate with the local scientific community.
Cell & Development Biology Programme - Ref. CDB-GL 0308
The programme is coordinated by V. Malhotra and comprises one senior group (I. Vernos) and one group leader (H. Lopez-Schier), as well as the Advanced Light Microscopy Unit headed by T. Zimmermann. The CRG is recruiting an additional group leader interested in cellular and molecular aspects of development.
Differentiation and Cancer Programme - Ref. CDC-GL 0308-02
This programme, coordinated by T. Graf, is looking for an additional group leader interested in mammalian stem cells, differentiation and mechanisms of cancer and in the fields described above.
Candidates should send a CV with list of publications, a brief research proposal and the addresses of at least 3 potential references to:
Miguel Beato, Director
Centre de Regulacio Genomica
Dr. Aiguader 88, 08003-Barcelona, Spain
rrhh@crg.es
Applications are invited from scientists or clinician-scientists working on aspects of the cardiovascular system in the zebrafish model. The position will be at the Assistant, Associate or Full Professor level. Applicants will be expected to hold a PhD or MD with relevant postdoctoral training, and to have a track record of outstanding research achievements at an international level that is successful in attracting, or has the potential to attract, highly competitive peer-reviewed funding.
Candidates with a distinguished record in any area of zebrafish cardiovasacular biology, including development, miRNA, cardiomyocyte structure and function, signal transduction, biophysics, stem cell biology and regeneration, epigenetics or computational biology will be given serious consideration. Those that couple the tools of molecular and developmental biology, biochemistry and cell biology are particularly encouraged to apply. The appointee will be provided with significant financial support to enable a high-quality program to be rapidly established, and will be eligible for an academic appointment at the University of New South Wales. Details of the Institute, its programs and faculty are available at: http://www.victorchang.org. The Institute will occupy new stand-alone research premises in the second half of 2008, with a state-of-the-art zebrafish aquaculture facility containing 1300 tanks, with capacity for expansion to 2700 tanks.
To apply, submit a C.V., the names/contact information of three referees, and a statement of past research achievements and anticipated research directions to
Ms. Renea Desfontaines
Human Resources Manager
Victor Chang Cardiac Research Institute
384 Victoria Street
Darlinghurst
NSW, 2010
Australia
or email: recruitment@victorchang.edu.au
Situated in Mill Hill, North West London, NIMR is the largest MRC institute, supporting some 70 research groups and 500 bench scientists. The Institute provides excellent training for researchers in a multi-disciplinary environment and is equipped with state of the art facilities. http://www.nimr.mrc.ac.uk/employment/
We are pleased to offer the following Research Technician positions in the Division of Developmental Biology:
Ref: NIMR08/161
Applications are invited for a permanent MRC funded Research Technician position studying the development of the liver. We are using the zebrafish Danio rerio as model organism. The work will involve a range of molecular, genetic and imaging techniques to analyze the mechanisms underlying organ specification and morphogenesis.
You should have experience in basic molecular biology techniques, as well as excellent technical, organisational and communication skills. A background in developmental biology, genetics or zebrafish biology would be advantageous. You should possess a degree in Life Sciences or equivalent qualification in an appropriate scientific discipline.
For informal inquires please contact Dr. Elke Ober, e-mail: eober@nimr.mrc.ac.uk and visit our website at http://www.nimr.mrc.ac.uk/devbiol/ober/.
Ref: NIMR08/162
Applications are invited for a 2 year fixed term EU funded Research Technician position studying heart development and the origin of congenital heart disease. We are using a range of vertebrate model organisms and cell culture techniques. The work will combine tissue culture work with a range of molecular and cell biology techniques to analyze the mechanisms underlying normal heart formation.
You should have experience in tissue culture and basic molecular biology techniques. You should have excellent technical, organisational and communication skills. A background in developmental biology, cell biology or embryology would be advantageous. Appropriate research experience and/or a higher qualification or a degree in an appropriate scientific discipline is required
For informal inquires please contact Dr. Timothy Mohun, e-mail: tmohun@nimr.mrc.ac.uk and visit our website at http://www.nimr.mrc.ac.uk/devbiol/mohun/.
Ref: NIMR08/163
Applications are invited for a permanent MRC funded Research Technician position studying limb development and the origin of congenital limb abnormalities. We are using a range of vertebrate model organisms and cell culture techniques. The work will involve a range of molecular, genetic and imaging techniques to analyze the mechanisms underlying normal limb formation and limb defects.
You should have experience in basic molecular biology techniques, as well as excellent technical, organisational and communication skills. A background in developmental biology or genetics or embryology would be advantageous. You should possess a higher qualification or a degree in an appropriate scientific discipline.
For informal inquires please contact Dr. Malcolm Logan, e-mail: mlogan@nimr.mrc.ac.uk and visit our website at http://www.nimr.mrc.ac.uk/devbiol/logan/.
Salary range is from £20,870-£23,822 per annum inclusive of Location Allowance. MRC final salary Pension Scheme is available.
Applications should now be made online at http://jobs.mrc.ac.uk. If you do not have internet access or you experience technical difficulties please call 01793 301157 quoting reference the appropriate reference.
The closing date for all positions is 24 April 2008.
The MRC is an Equal Opportunities Employer
A post-doctoral position is available at the University of Michigan Medical Center to study adult neurogenesis in the zebrafish forebrain. The project involves generation of conditional transgenic reporter fish for lineage mapping, analysis of integration patterns of adult-born neurons, and the development of a telencephalic injury model in the fish to study regeneration. Similar work with transgenic mouse models is also possible for interested applicants. Applicants should have a PhD or MD degree, and experience with genetic and neuroanatomical approaches is desired.
Interested applicants should send a cover letter highlighting research experience and interests along with a CV and contacts for 3 references to:
Jack M. Parent, MD
Associate Professor
Department of Neurology and
Neuroscience Graduate Program
University of Michigan Medical Center
5021 BSRB, 109 Zina Pitcher Place
Ann Arbor, MI 48109-2200
parent@umich.edu
St. Jude Children's Research Hospital, located in Memphis, Tennessee, is a premier center for research and treatment of potentially fatal childhood diseases, including cancer and certain blood, genetic, and immunodeficiency disorders. The hospital's mission is to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment. St. Jude is dedicated to providing unsurpassed patient care and to advancing the health of children through biomedical research.
Currently, St. Jude Children's Research Hospital has an opening for a Senior Research Technologist (Job Number 15506).
The Senior Research Technologist in the Chemical Biology and Therapeutics Department operates as an advanced-level Research Technologist by assisting the principal investigator with the data collection and analysis for research projects. The incumbent properly conducts specific projects, maintains efficient laboratory operations and may assist in training other laboratory personnel. The Technologist also performs other duties as assigned or directed in order to meet the goals and objectives of the department. Our research area is focused on the use of zebrafish to screen small molecule libraries to identify biologically active compounds.
Requirements:
Bachelor's degree in an appropriate scientific field plus a minimum of 3 years (post-degree) relevant work experience in a research environment is required or
Master's degree in an appropriate scientific field plus a minimum of 2 years (post-degree) relevant research experience is required, or
PhD with no additional experience is required
Background in molecular biology, genetics, and/or developmental biology is required
Experience/strong interest in working with zebrafish is highly desired
St. Jude offers a positive working culture, professional advancement, & competitive compensation. Qualified applicants may apply for this position or others via our online process at http://www.stjude.org/jobs
An Equal Opportunity Employer
The University of Oregon Institute of Neuroscience is currently recruiting a Senior Research Assistant to work in a research laboratory investigating mechanisms of zebrafish embryonic development.
This position requires a self-motivated person with excellent organizational, managerial, technical, and communication skills to oversee day-to-day laboratory operations and to participate in a variety of experiments with lab members.
Specific duties include:
Oversee day-to-day operations of the research lab
Train new members of lab in relevant techniques
Oversee maintenance of all lab zebrafish stocks
Assist lab members with a variety of experiments
Supervise lab staff
Maintain lab databases
The ability to conduct independent research
Required skills and experience:
Excellent problem solving skills
Excellent interpersonal communication skills
Supervisory or lab management experience
Ability to work well in a team environment
Excellent organizational ability
Familiarity with general computer software
General molecular biology and genetics lab experience
Preferred skills and experience:
Working with zebrafish
Light microscopy experience
Education and experience:
Bachelor's or Master's degree in biology or related field
Six years relevant experience
Send cv, letter of interest, and the names and phone numbers of three references to:
Peg Morrow
Institute of Neuroscience
1254 University of Oregon
Eugene, OR 97403-1254
FAX: (541)346-4548
morrow@uoneuro.uoregon.edu
The University of Oregon is an AA/EO/ADA institution committed to cultural diversity. We invite applications from candidates who share our commitment to diversity. Review of applications will begin [4 weeks from 1st announcement]. Position will remain open until filled.
The University of Oregon Institute of Neuroscience has an opening for a Research Assistant/Lab Manager in a research laboratory investigating mechanisms of zebrafish development. This position will be responsible for managing day-to-day laboratory operations, supervising and training laboratory personnel, and independently carrying out research for publication. This position will also be responsible for maintaining all laboratory zebrafish stocks.
Preference will be given to applicants with lab management experience; other experience preferential experience includes zebrafish research (cellular, molecular, and genetic techniques), light microscopy, computer software.
Minimum qualifications: Master's degree in Biology or related field plus two years of relevant experience (or five years experience and Bachelor's degree in biology or related field). Starting salary $35,000-$45,000 depending upon experience.
Send cv, letter of interest, and the names and phone numbers of three references to:
Peg Morrow
Institute of Neuroscience
1254 University of Oregon
Eugene, OR 97403-1254
FAX: (541)346-4548
morrow@uoneuro.uoregon.edu
The University of Oregon is an AA/EO/ADA institution committed to cultural diversity. We invite applications from candidates who share our commitment to diversity. Review of applications will begin [4 weeks from 1st announcement]. Position will remain open until filled.
Search committee: Judith Eisen, Julie Kuhlman, Karen Guillemin, Yasuko Honjo
The Cell Biology department at Duke University is seeking to hire a highly motivated full-time manager for its zebrafish facility. A BA/BS in Biology or Marine biology is required, and experience in aquatic animal care is required.
Duties of the facility manger include recording and monitoring water quality, monitoring fish health in cooperation with veterinarians, organizing and ordering supplies, supervising animal technicians, equipment care and optimization, training of new personnel, emergency management (including some weekend/holiday work), maintenance of laboratory strains including breeding and embryo care, cryopreservation of stocks, sending and receiving animals, and supervision of the quarantine facility.
To apply, please email a CV with the names and contact information of three references to:
Kenneth Poss
Department of Cell Biology
Box 3709
Duke University Medical Center
Durham, NC 27710
FAX: 919-684-5481
Email: k.poss@cellbio.duke.edu
The Department of Genetics (http://lifesci.rutgers.edu/~genetics) and the Human Genetics Institute of Rutgers University seek an outstanding scientist to fill one of several new positions in human genetics. Researchers seeking a well-funded, diverse, and interactive department are encouraged to apply. Research areas of interest include but are not limited to: population genetics, computational genetics, developmental genetics, chromatin remodeling and epigenetics, complex disease gene discovery, cancer genetics, neurogenetics and neuropsychiatric genetics, and functional genomics.
Candidates must have a Ph.D. and/or M.D., demonstrated ability to independently conduct and publish significant research, a strong record of grant support and an interest in teaching at the undergraduate and graduate levels. Appointments will be made at the Associate or Full Professor level, tenured or tenure-track, consistent with the candidate's history and credentials.
Laboratory space will be provided in the newly constructed, state-of-the-art Genetics/Human Genetics Institute on Rutgers' Busch Campus. We are part of a vibrant life sciences community including the Waksman Institute, the Center for Advanced Biotechnology and Medicine, the Center of Alcohol Studies, the Environmental and Occupational Health Sciences Institute, and the Robert Wood Johnson Medical School. The campus is located in central New Jersey, close to New York City, Philadelphia, beaches, and countryside.
Applicants should submit a CV, a statement of research interests, and full contact information for three individuals willing to provide a detailed evaluation of the candidate using the URL http://Genetics-Facsearch.rutgers.edu or to Linda Brzustowicz, Search Committee Chair, Human Genetics Institute of New Jersey, Rutgers University, 145 Bevier Road, Room 231, Piscataway, NJ 08854-8082. Review of applications will begin immediately and continue until a candidate is appointed.
Rutgers University is an equal opportunity/affirmative action employer.
Summit plc is a leading UK biotechnology company that uses two innovative technology platforms to discover and develop proprietary new drugs, targeting serious diseases with unmet medical need as well as providing high-value drug discovery services to the pharmaceutical industry.
As part of our continued expansion we are looking to recruit the following position:
Senior Scientist (Zebrafish Toxicology) : Ref: SSC.ZT
Oxford
In this challenging role applicants will be expected to demonstrate excellent technical skills combined with the ability to lead and motivate a small team. Acting as deputy to the Head of Toxicology, this position will be responsible for a variety of duties essential to the successful operations of the unit.
Key accountabilities of the role are:
* Quality control and interpretation of zebrafish toxicity data provided by Research Scientists
* Production of quality reports to a standardised format for both external clients and internal projects
* Ensure the accurate and timely delivery of client contracts
* Maintain a complete understanding of all current screens (endpoints and protocol)
* Line manage a small team of Research Scientists to high standards of efficiency, accuracy and health and safety
* Oversee scheduling of assays to ensure productivity and efficiency of operation
* Identify and order repeat assays where necessary
* Maintain accurate records
* Contribute to continual improvements in efficiency and accuracy of all assessments
In addition, the successful candidate will be required to perform established zebrafish screening assays to Standard Operating Procedures (SOP's), as well as assisting in training and supporting other staff and departments as required. Candidates will require a PhD in biology, toxicology or a related field and must have a proven track record of achievement. In addition the successful candidate will have extensive experience in writing reports and interpreting data, and will demonstrate excellent practical skills in various techniques. Proven ability in designing novel assays as well as following established protocols would be advantageous. He or she will have proven line management experience and will be comfortable working both independently and as part of a team. Excellent presentation, organisation and numerical skills and the ability to work to deadlines is essential.
If you are looking for an exciting opportunity to further your career within a rapidly growing biotechnology company, please send a CV with covering letter, stating the reference of the position you are applying for, to:
careers@summitplc.com or Closing date: 30th April 2008
Recruitment
Summit plc
91 Milton Park
Abingdon, Oxon
OX14 4RY, UK
http://www.summitplc.com
A postdoctoral position will be available by October 2008 to study mechanisms of early development in the frog Xenopus laevis and the zebrafish Danio rerio. We use molecular and genetic screens to identify genes that regulate development, with an emphasis on signaling pathways and cell interactions. Recent projects focus on the molecular control of axis formation in the embryo, and on the regulation of cell movements during gastrulation by the Wnt pathway. In another project we are studying the Fgf pathway, its role in neural crest formation, and modifiers of Fgf signaling that modulate its activity in the embryo. Experience in developmental and molecular biology is desired. Please send a cover letter, CV, and three letters of reference to:
Igor B. Dawid
Laboratory of Molecular Genetics
Building 6B, Room 413
NICHD, NIH
Bethesda MD 20892
E-mail Igor B. Dawid: idawid@nih.gov
http://dir.nichd.nih.gov/lmg/lmgdevb.htm
The University of Maine's School of Biology and Ecology is seeking a Research Assistant to investigate muscle and satellite cell specification using the zebrafish model. Research is focused on understanding the mechanisms by which muscle fibers form and attach to tendons during embryonic development. The Research Assistant will use embryological, molecular, genetic, and pharmacological methods to design and execute experiments.
Essential Duties / Responsibilities:
Determining the role of binding to laminin in satellite cell specification and regulation of myogenic regulatory factor transcription. This includes: genetic engineering, microinjections of DNA, RNA and dyes, cell transplantation,
immunohistochemistry, and various microscopy methods such as confocal microscopy, electron microscopy, and using a Zeiss Apotome. In addition, this position will entail extensive time-lapse analysis;
Fish Husbandry: Stock keeping, and maintenance of approximately 25 fish lines (includes PCR genotyping);
Provides technical assistance to all lab members;
Performs other reasonably related duties as assigned (supervision of undergraduate student workers, ordering, etc.).
Qualifications:
Bachelors Degree in Biological Sciences required. Applicants should have experience with molecular techniques that include DNA purification, PCR, and cloning. Basic computing skills, light microscopy skills, and ability to manipulate small objects
under a stereomicroscope for extended periods of time are required. Basic knowledge of genetics beneficial.
Salary:
$25,316-$33,000, 12 month full-time position plus excellent benefits.~ This position is contingent on the receipt of funding from outside the University and satisfactory job performance.
To apply: Send resume and contact information for at least three references (including supervisors from previous positions) to:
Clarissa Henry
School of Biology and Ecology
University of Maine
217 Hitchner Hall
Orono, ME 04469
or clarissa.henry@umit.maine.edu
(Ph: 207-581-2816)
The University of Maine is an Affirmative Action / Equal Opportunity Employer
A postdoc position is available for individuals interested in studying molecular and cellular mechanisms of vertebrate limb and heart development. We are studying T-box transcription factors, which play key roles in limb and heart development in virtually all vertebrates. In particular, the lab is focusing on how the transcription factors work in a protein network to achieve their regulatory functions. We are employing a diverse spectrum of animal models including zebrafish as a more amenable system for life embryo imaging and genetic studies. The Research Center - located in Chicago's dynamic Lincoln Park area - provides new, state of the art research facilities and an interactive training environment with an international group of faculty and trainees. Applicants should be self-motivated, creative and have excellent communication skills; they are expected to have solid background in molecular biology, biochemistry, and/or cell biology. Experience with zebrafish work would be desirable. Salary support is available through an NIH grant, however, candidates are encouraged to apply for their own fellowship. Send CV including list of publications and names of references to:
Hans-Georg Simon, Ph.D.
Northwestern University
Feinberg School of Medicine
Children's Memorial Research Center (CMRC)
2300 Children's Plaza
Box 204
Chicago, IL
60614
Research Center website:
http://www.childrensmrc.org/simon/
E-mail Hans-Georg Simon:
hgsimon@northwestern.edu
Postdoctoral Fellowship: A Xenopus tropicalis Mutant Resource
An NIH-funded 3-year postdoctoral fellowship is available to develop a reverse genetic resource for Xenopus tropicalis and characterize mutations in specific genes using genomics techniques, in a collaboration with groups at the Sanger Institute and UC Berkeley. You should have extensive laboratory experience, molecular biology skills, and a strong interest in developmental genetics. The successful applicant will be able work semi-independently, but also will be committed to helping build a new genetics community.
Situated in Mill Hill, North West London, NIMR is the largest Medical Research Council institute, supporting some 70 research groups and 500 bench scientists. The Institute provides excellent training for researchers in a multi-disciplinary environment and is equipped with state of the art facilities. http://www.nimr.mrc.ac.uk/employment/
To apply, see http://www.nimr.mrc.ac.uk/jobs/2008/070/
For further project details please visit http://www.nimr.mrc.ac.uk/devbiol/zimmerman/
Informal enquires can be made to Lyle Zimmerman on 0208 816 2114 or email lzimmer@nimr.mrc.ac.uk
Salary is from £26,808 to £32,488 per annum inclusive of Location Allowance. MRC final salary Pension Scheme is available.
Contact:
Hughes, Stacey
Location: United Kingdom, London
Submit Email recruitment@ssc.mrc.ac.uk
The closing date is 6 March 2008.
Ref: NIMR08/070
Research Assistant / Technician position at Centre for Genomic Regulation in Barcelona, Spain
JOB TITLE: Technician
JOB DESCRIPTION: A Research Assistant / Technician position is available immediately in the Lopez-Schier Laboratory, at the Centre for Genomic Regulation in Barcelona, Spain. Our lab is currently formed by PI, four graduate students and three postdocs. We investigate the regeneration and reinnervation of sensory cells using the zebrafish as a model system.
We are looking for a motivated person with excellent organisational and technical skills to run experiments at the bench, and also oversee the operation of the lab. Ability to work well within a team is a must. The position is project-funded and the salary level will depend upon experience.
Languages: Fluent in English.
The ideal qualifications are a Bachelor's degree in Biology or a related field, plus extensive experience in molecular biology and/or biochemistry. The postholder will be responsible for microinjecting DNA into fish eggs, assist the members of the lab with molecular biological experiments, maintains laboratory databases and perform orderings for laboratory supplies.
Please, send a letter of interest, a complete curriculum vitæ and the names of three references to:
Dr. Hernan Lopez-Schier
Laboratory of Sensory Cell Biology & Organogenesis
Centre de Regulacio Genomica - PRBB
Doctor Aiguader, 88
(08003) Barcelona
Spain
TE (office): +34 93 316 0134
TE (lab): +34 93 316 0130
Fax: +34 93 316 0099
URL: http://www.crg.es/hernan_lopez_schier
ANIMAL DEVELOPMENTAL BIOLOGIST
The Department of Biological Sciences at SUNY Brockport requests applications for a tenure track position at the rank of Assistant Professor starting Fall 2008. The successful candidate will teach an upper-division course in developmental biology and appropriate undergraduate and graduate (M.S. level) courses in his or her area of expertise, and contribute to the teaching mission of the department. The candidate is also expected to develop an active research program utilizing undergraduates and Master's students, and to seek external funding to support the research. We are particularly interested in persons who utilize a combination of cellular, molecular, and genetic approaches in studying development. A Ph.D. is required, and post-doctoral and teaching experience are highly preferred.
Applicants should apply on line at http://www.brockportrecruit.org and submit the following information: letter of application, curriculum vitae, and statements of teaching philosophy, and research plans. All positions are subject to final budgetary approval.
Postdoctoral position - zebrafish model for heart diseases A NIH-funded post-doctoral fellow position is available in the laboratory of Dr. Xiaolei Xu. The successful applicant will join a team that is taking a genetic and genomic approach to study molecular mechanism of heart failure and congenital heart diseases using zebrafish as an animal model. The project will start with cloning and characterizing cardiac mutants from a collection of 45 embryonic lethal mutants that have been identified from a transposon-based insertional mutagenesis screen. Applications are invited from candidates who have a background in developmental biology with strong molecular biology skills. Qualified candidates must be self-motivated and have a strong commitment to basic research. Mayo Clinic College of Medicine is a not-for-profit organization that integrates basic research with clinical practices. Mayo offers an attractive benefit package. Salary will be highly competitive.
Further enquires regarding the scope and detail of the project should be addressed to: xu.xiaolei@mayo.edu or visit http://mayoresearch.mayo.edu/mayo/research/zebrafish/. Applications, including curriculum vitae and bibliography, summary of past accomplishments and future plan, and the names of three references, should be sent to:
Xiaolei Xu, PhD.
Department of Biochemistry and Molecular Biology
Division of Cardiovascular Diseases
Mayo Clinic College of Medicine
Stabile 4-10
200 First Street SW
Rochester, MN USA 55905
Email: xu.xiaolei@mayo.edu
A post-doctoral position is available at the Medical College of Wisconsin to study the molecular and genetic basis of glaucoma-associated phenotypes. Glaucoma is a neurodegenerative disorder of the optic nerve. We are currently initiating a genetic screen in zebrafish to identify adult mutants which show phenotypes associated with this disease. Successful candidates will have the opportunity to participate in this screen or will pursue reverse-genetic approaches to study glaucoma-associated phenotypes. Experience with molecular, genetic, cell biological approaches is desired.
Interested applicants should send a cover letter highlighting research experience and interests along with a CV and contacts for 3 references to:
Brian A. Link, PhD
Associate Professor
Department of Cell Biology, Neurobiology and Anatomy
Medical College of Wisconsin
Milwaukee, Wisconsin 53226
blink@mcw.edu
Additional description of projects at: http://www.mcw.edu/display/router.asp?docid=17113
A post-doctoral position is available at the Medical College of Wisconsin to study neurogenesis in the developing zebrafish and mouse retina. Specific areas of interest with this project include the role of polarized signaling, control of cell cycle kinetics, and endosome-mediated signal transduction in retinal neuroepithelial progenitor cells and how these processes influence cell cycle exit. Experience with cell biological, genetic, and imaging approaches are desired.
Interested applicants should send a cover letter highlighting research experience and interests along with a CV and contacts for 3 references to:
Brian A. Link, PhD
Associate Professor
Department of Cell Biology, Neurobiology and Anatomy
Medical College of Wisconsin
Milwaukee, Wisconsin 53226
blink@mcw.edu
Additional description of projects at: http://www.mcw.edu/display/router.asp?docid=17113
A position for a Research technician (M/F) is available immediately at the The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital (NKI-AVL), in the group of Dr. Anna-Pavlina Haramis at the Division of Molecular Genetics.
Project information: Cancer is a multifactorial disease and exhibits many features of embryonic development. We are interested in understanding the role of signaling pathways operating during vertebrate development that when deregulated lead to cancer. We use the zebrafish as an experimental model system to elucidate the developmental roles of tumor suppressors or oncogenes. We perform gain and loss of function experiments in embryos and characterize the phenotype of zebrafish mutants in these genes.
Requirements: We are looking for an enthusiastic research technician, with a motivation to become familiar with genetic, in vivo experiments in zebrafish. The work will involve the use of molecular biology techniques, such as genotyping mutant and transgenic lines (DNA isolation, PCR, agarose gel electrophoresis, and/or fluorescence microscopy); microinjection of DNA, RNA and morpholinos in zebrafish embryos; immunocytochemistry. Experience with immunocytochemistry techniques is preferred but not required.
Employment conditions:The temporary employment will initially be for a period of 2 years, with a possibility of 2 years extension. The gross salary per month is € 1.930,00 to € 2602,00 according to the FWG-function group 45 and depends on previous experience. The terms of employment will be in accordance with the CAO for Hospitals.
For information: For further information please contact Anna-Pavlina Haramis, telephone +31-20-512 2054, e-mail: a.haramis@nki.nl
Interested? You can sent your written application (including your resume) to work@nki.nl or to:
The Netherlands Cancer Institute
Antoni van Leeuwenhoek Hospital
Personnel Department
Plesmanlaan 121
1066 CX Amsterdam
The Netherlands
Please refer to the reference number 019/08 when applying for this.
Postdoctoral position is available at the University of California San Francisco (UCSF), to use molecular genetic approaches to study the development and function of the nervous system and melanocyte biology in zebrafish.
Requirement:
Recent PhD (or MD) degree in developmental cell biology, genetics, neurobiology, or other related fields, and publications in peer-reviewed journals. Send CV together with the names of three referees to: su.guo@ucsf.edu
Postdoctoral Research Scientists (ref. no. 04-2008)
Department of Tissue Morphogenesis, Director Ralf H. Adams
Max-Planck Institute for Molecular Biomedicine, Muenster, Germany
http://www.mpi-muenster.mpg.de/indexe.shtml
Blood vessels play essential roles in vertebrate organisms and are also directly involved in a range of disease conditions such as cancer. We are studying the signaling processes controlling the angiogenic growth of the vasculature, the interactions between the different cell types forming the vessel wall and the communication between blood vessels and the surrounding tissues.
Technical approaches include genetic studies in mouse or zebrafish, confocal, multiphoton and time-lapse microscopy, immunohistochemistry, cell/tissue culture, biochemistry, molecular biology and bioinformatics.
We invite applications by enthusiastic, committed and talented prospective postdoctoral fellows at senior or junior level who wish to join our new department to study cellular and molecular processes contributing to angiogenesis in zebrafish.
The Max-Planck Institute for Molecular Biomedicine offers an excellent research environment with core facilities such as Fluorescence Activated Cell Sorting, electron microscopy, research animal unit and transgenic service. The institute offers a very international environment and knowledge in the German language is not essential. Fellowships are offered initially for two or three years with the possibility of extension.
Please send your application, which should in include your CV, a short summary of your current/previous work and research interests as well as the names of three referees for reference letters, to
thielen@vw.mpi-muenster.mpg.de
or by mail to
Mrs Wenke Thielen
Administration
Max Planck Institute for Molecular Biomedicine
Roentgenstrasse 20
D-48149 Muenster
Germany
Postdoctoral and Ph.D. positions are available at the Max Planck Institute for Medical Research in Heidelberg, Germany to join our work on investigating development and function of neuronal circuits within the hypothalamus. The hypothalamus, a key integrative center in the brain, controls immense number of crucial bodily functions such as sleep, reproduction, food intake, and stress response yet relatively little is known about its development. We combine forward genetics screen, extensive confocal live imaging and biochemical methods to analyze 1) basic paradigms of hypothalamic neuronal specification, and 2) connectivity and functional properties of select hypothalamic circuits. We are particularly interested in the circuitry underlying stress response whose hyperactivation is implicated in depression.
Interested postdoc candidate must have a Ph.D. in biological sciences, deep interest in neuroscience and excellent background in neuroanatomy. Expertise in live imaging using confocal microscopy is strongly preferred and solid molecular biology experience is desirable. Interested Ph.D candidate must have a deep interest in developmental neurobiology and a genuine interest in pursuing research science as a career. Practical experiences in neurobiology and/or developmental biology are desirable. Prior experience with zebrafish is not mandatory.
This will be a terrific opportunity for the candidate to build a career in an area of great biomedical relevance using a model organism ideally suited for neuronal circuit analysis due to its transparency and tractability. Max Planck Institute for Medical Research provides a stimulating interdisciplinary environment and a state-of-art infrastructure for imaging. Start date is flexible but preferably around July 1, 2008.
To apply please send an email to Dr. Soojin Ryu at soojin.ryu@mpimf-heidelberg.mpg.de with the subject line "application" followed by your name and include a single attachment (word or PDF file) containing:
1-2 page cover letter summarizing scientific accomplishments, research and career goals, reasons for the interest in our project, and expected date of availability
CV with a complete list of publications
Contact information for three references
A postdoctoral position is available immediately in the Sumanas laboratory in the Division of Developmental Biology at the Cincinnati Children's Hospital Medical Center. Research in the laboratory utilizes zebrafish as a model to study molecular mechanisms of vasculogenesis and angiogenesis. We are investigating detailed mechanisms of angioblast formation, specification, differentiation and proliferation and identifying new genes participating in these processes. For more information please refer to http://www.cincinnatichildrens.org/research/div/dev-biology/fs/fac/saulius-sumanas.htm Experience in molecular biology and knowledge of developmental biology is required. Please send a CV and the reference names and contact information to:
Saulius Sumanas, Ph.D.
Assistant Professor
Division of Developmental Biology, ML7007
Cincinnati Children's Hospital Medical Center
3333 Burnet Ave., S-3,206
Cincinnati, OH 45229
Tel.: 513-803-0435
E-mail: saulius.sumanas@cchmc.org
Sanofi-aventis is devoted to the treatment and prevention of diseases through the research and development of innovating pharmaceuticals and human vaccines concerning 7 major therapeutic areas: cardiovascular, thrombosis, central nervous system, oncology, metabolic disorders, internal medicine and vaccines. Our group is present in more than 100 countries and over the 5 continents. http://www.sanofi-aventis.com
One postdoctoral position is available in the Exploratory Department / Biochemistry at the research center of Toulouse. The candidate will design and implement new experimental models intended for the identification of anti-tuberculous drugs and for the understanding of their mode of action, based on the Zebrafish/Mycobacterium marinum infection model.
The successful candidate must have a Ph.D. Experience in the manipulation of Zebrafish and experience in microscopy techniques such as DIC (Differential Interference Contrast) and/or DCC (Confocal microscopy) is required. Background knowledge in microbiology will be appreciated as well.
Fluent in English
French appreciated
18 months fixed-term contract
Starting date: 1st of April 2008
Gross salary: 39702 € /year
Please send e-mail application including detailed CV to:
Astrid.Rey@Sanofi-Aventis.com
Belen.Barrio-Perez@Sanofi-Aventis.com
Candidate must have experience with basic molecular cloning techniques and zebrafish work, including: restriction analysis, cloning and vector design, DNA isolation, DNA sequencing, and analysis of GenBank sequence information, zebrafish embryo injection and gene function and expression characterization.
Independently plan and design well-controlled experiments. Adapt or modify experimental methods to achieve technical results. Make detailed observations, independently analyze data, and interpret results. Maintain complete and thorough lab notebook.
Prepare technical reports, product summaries, and protocols. Effectively communicate and present scientific ideas to a broader audience. Participate in scientific conferences and contribute to scientific journals.
For more detailed information please visit our website http://www.biobide.es or contact us (see below)
Requirements: Requires a minimum of a bachelor's degree and 4 years of relevant laboratory experience or a master's degree and 2 years of experience.
Educational Requirements: Requires a Bachelor's degree in Biology, Chemistry, Biochemistry, or other related discipline, or the equivalent knowledge and experience.
Spanish is not required
Contact information:
Carles Callol callol@biobide.es
Phone: +34943309360
Fax: +34943309370
TWO POST-DOCTORAL POSITIONS ARE AVAILABLE TO STUDY SYNAPTIC FUNCTION IN THE VISUAL SYSTEM OF ZEBRAFISH
1. SYNAPTIC PROCESSING OF VISUAL INFORMATION IN VIVO INVESTIGATED BY MULTIPHOTON MICROSCOPY IN COMBINATION WITH FLUORESCENT REPORTER PROTEINS. We have recently developed reporters for monitoring calcium influx and vesicle fusion in synaptic terminals and are using these to monitor synaptic activity in large populations of neurons within intact circuits. We are particularly interested in the function of ribbon synapses in the retina, but also aim to investigate the retinal output received by neurons in the tectum. The overall aim is to understand how these synapses transfer information contained within a visual stimulus.
2. THE MOLECULAR EVENTS INVOLVED IN EXOCYTOSIS AND ENDOCYTOSIS AT RIBBON SYNAPSES INVESTIGATED USING ISOLATED RETINAL NEURONS AND TOTAL INTERNAL REFLECTION FLUORESCENCE MICROSCOPY (TIRFM). This technique allows the visualization of synaptic vesicles and fluorescent molecules within about 100 nm of the surface membrane. We have generated fish that express fluorescent fusion proteins regulating vesicle behaviour at or near the active zone and are using these to monitor the vesicle cycle in real-time. The basic aim is to better understand the processes that control the translocation and docking of vesicles before fusion, as well as the retrieval of vesicles after fusion
Both positions are in the laboratory of Leon Lagnado in the Neurobiology Division at the MRC Laboratory of Molecular Biology, Cambridge. The projects use a combination of molecular biology, zebrafish genetics, advanced imaging methods and electrophysiology. Experience in at least one of these techniques would be required, together with the desire to learn one or more of the others. A strong interest in the function of the nervous system is essential, and more specific interests in synapses, vision or zebrafish would be an advantage. If you are interested please contact Leon by e-mail with your CV and the names of two referees (LL1@mrc-lmb.cam.ac.uk). Further information can be obtained by contacting Leon directly and from our website (http://www2.mrc-lmb.cam.ac.uk/groups/LL/index.html). Both positions are funded by the Wellcome Trust for a period up to five years.
A graduate student or PDF position is available starting immediately (Jan 2008) in a neural development lab in the Regeneration program of the Hotchkiss Brain Institute at the University of Calgary, under the supervision of Dr. Sarah McFarlane. Research in this lab is focused on understanding two fundamental questions in developmental neurobiology: how neurons acquire their adult phenotype and how they connect up to one another. The project involves investigating the molecular mechanisms involved in the developing visual system of zebrafish, using in vivo gene transfer and morpholino approaches. Work will be done in collaboration with Dr. Sarah Childs (http://homepages.ucalgary.ca/~schilds/Childs.htm), an expert in the area of zebrafish angiogenesis.
The Hotchkiss Brain Institute is situated in the Health Sciences Centre at the Foothills Hospital, which is close to the main campus of the Univ. of Calgary. To enquire about this position please contact me at smcfarla@ucalgary.ca. To apply for a position, send a copy of your transcripts (unofficial is fine) and resume, and indicate three individuals who would be willing to provide a reference.
Dr. Sarah McFarlane
Univ. of Calgary, HBI
HSC, Rm. 2207
3330 Hospital Drive, NW
Calgary, Alberta
T2N 4N1
email: smcfarla@ ucalgary.ca
http://www.ucalgary.ca/smcfarla/
TREAT-OA (European Framework Program 7) represents a large-scale collaborative, integrated, trans-disciplinary project utilizing a resource of 28,000 OA phenotyped subjects with available genome-wide association scan data as well as leading basic science laboratories and technologies. The key scientific objectives of TREAT-OA are:
- to identify genes and biochemical markers consistently associated with risk and progression of OA
- define their function in the molecular pathways involved in disease aetiology
- develop in vivo models by the use of transgenic animal laboratory OA model systems.
Within this project we are currently looking for a post-doctoral fellow to join our research team focusing on the functional studies (item 2). Specifically, the work will involve identification and cloning and in situ studies of zebrafish orthologues of human disease genes. Next, gain and loss of function studies in the fish will be carried out to identify signaling pathways associated with those genes. Finally, generation of stable mutant fish lines and phenotypic analysis will be carried out on selected genes. The tools to perform this research project consist of advanced molecular embryology using zebrafish model, histology and analysis of gene expression by in situ hybridization, immunofluorescence and quantitative PCR.
A successful candidate will have a prior training in the zebrafish developmental biology. Knowledge of the early fish development as well as advanced molecular biology would be an advantage. The candidate should be able to work independently in a team-oriented project. Additionally the candidate must be fluent in spoken and written English. The starting date for the project is October 2008 and the project duration is 3 years.
For further information, please contact Prof. Frank Luyten (frank.luyten@uz.kuleuven.be) or Prof. Przemko Tylzanowski (przemko@med.kuleuven.be). To apply, please send a motivation letter with names and contact coordinates (email and/or phone) of two referees to the above email addresses.
University of Leuven is located 20 km from Brussels (Belgium) in a college town of Leuven. Belgium has been ranked number 1 country for academic research in 2007 by The Scientist (http://www.the-scientist.com/2007/11/1/65/1/). Disclaimer: http://www.kuleuven.be/cwis/email_disclaimer.htm for more information.