Technical Assistant II/Technical Associate I . (Whitehead Institute for Biomedical Research, Cambridge, MA ) . Posted 02 July 2009
Postdoctoral Fellow. (North Carolina Central University, Durham, NC) . Posted 17 June 2009
Postdoctoral Position . (North Carolina Central University, Kannapolis, NC) . Posted 11 June 2009
Postdoctoral Position . (University of Southern California Keck School of Medicine) . Posted 09 June 2009
Postdoctoral Position . (National Human Genome Research Institute, Bethesda, MD) . Posted 08 June 2009
PhD Student Position. (University of Manchester, UK) . Posted 03 June 2009
Postdoctoral Position. (Biomedical Sciences Institutes, Singapore) . Posted 27 May 2009
PhD Student Position. (Technical University Munich) . Posted 20 May 2009
Postdoctoral Position . (University of California San Francisco) . Posted 12 May 2009
Research Technician. (Yale University. New Haven, CT) . Posted 05 May 2009
Postdoctoral Position. (NIH Clinical Center, Bethesda, Maryland) . Posted 20 April 2009
Projects Manager and Technician Positions. ( University of Massachusetts Medical School) . Posted 01 April 2009
Postdoctoral Position . (Cincinnati Children's Hospital Medical Center ) . Posted 31 March 2009
Postdoctoral Position . (University of Pittsburgh) . Posted 31 March 2009
Research Technician. (New York University School of Medicine) . Posted 24 March 2009
Postdoctoral Positions. (Tufts University Medical School, Boston, MA) . Posted 24 March 2009
Postdoctoral Position . (Genome Institute of Singapore, Singapore.) . Posted 09 March 2009
Scientific Technician. (Fox Chase Cancer Center, Philadelphia, PA) . Posted 09 March 2009
Postdoctoral Position . (University of Cologne, Germany) . Posted 03 March 2009
Postdoctoral Position . (Max-Delbrueck-Center for Molecular Medicine, Berlin, Germany) . Posted 23 February 2009
Postdoctoral Position . (Institute of Functional Genomics of Lyon (IGFL) at Ecole Normale Superieure de Lyon (France) ) . Posted 23 February 2009
Research Technician. (University of Sydney) . Posted 10 February 2009
Postdoctoral Position. (University of Sydney) . Posted 10 February 2009
Postdoctoral Positions. (University of Notre Dame) . Posted 10 February 2009
Postdoctoral Position. (Sodertorn University/Karolinska Institute, Huddinge, Sweden) . Posted 29 January 2009
Postdoctoral Position. (Harvard Medical School and Brigham and Women's Hospital, Boston) . Posted 26 January 2009
Physiological Genomicist Assistant Professor Position. (North Dakota State University) . Posted 20 January 2009
Evolutionary Developmental Biologist Assistant Professor Position. (North Dakota State University) . Posted 20 January 2009
Postdoctoral Fellowship . (Children's Hospital and Harvard Medical School Boston) . Posted 20 January 2009
Zebrafish Research Associate - Part Time. (Phylonix) . Posted 14 January 2009
Postdoctoral Position. (University of Iowa) . Posted 06 January 2009
A postdoctoral position is available at Cancer Research Program, Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University, Durham, NC, to study molecular mechanism of oro-esophageal disease in zebrafish. We use transgenic approaches to study how oro-esophageal disease may develop in adult fish. Lab information can be found at http://ariel.acc.nccu.edu/Academics/BBRI/personnel/chen.htm
Interested applicants should have a Ph.D. degree with experience in molecular biology and zebrafish. To apply, please send a curriculum vitae with a brief description of research experience and interests, and the names of 3 references (with phone numbers) via e-mail to Dr. Xiaoxin (Luke) Chen (lchen@nccu.edu).
A postdoctoral position is available at the North Carolina Central University, located at the North Carolina Research Campus in Kannapolis, NC, to study cardiovascular development in zebrafish. We use molecular, cellular, genetic, and transgenic approaches to study the specification, patterning, and differentiation of the developing cardiovascular system. Our areas of research interest include: G protein and GPCRs signaling for the developemnt of arteries, veins, and angiogenesis (Cell 2002, 111:647; Development 2003, 130:3639; Blood 2006, 108:160; Developmental Biology 2008, 323:31); natural products for modulation of embryonic cardiovascular networks, and what genetic pathways that mediate their biological function; and discovery of therapeutic molecules from natural products for treating cancer and cardiovascular diseases.
The scientific environment, resources, and support in the North Carolina Research Campus are superb. See http://www.ncresearchcampus.net/about-ncrc/ for additional information.
Interested applicants should have a Ph.D. or M.D. degree(s). To apply, send a curriculum vitae, bibliography, cover letter with a brief description of research experience and interests, and the names of 3 references (with phone numbers) via e-mail to TinChung Leung tleung@nccu.edu.
Our research campus is dedicated to building a diverse community in its training and employment programs.
A fully funded postdoctoral position is available to study the formation and patterning of the vertebrate head skeleton. Potential research projects, which are funded by recent CIRM and NIH awards, include the following:
Epigenetic remodeling events in neural crest formation and skeletal regeneration, using both zebrafish and mammalian embryonic stem cell systems
Genomic analysis of regional skeletal patterning, using a new library of fluorescent reporter and Gal4/UAS transgenic lines
Use of time-lapse microscopy to understand complex tissue interactions during facial morphogenesis
Applicants should have a background in developmental or stem cell biology. Salary support will be at current NIH standards, though individuals are encouraged to apply for their own funding upon arrival. More information about the Crump lab is available at http://stemcell.usc.edu/gage-crump-phd.html. To apply, send a curriculum vitae, a brief description of research experience and interests, and the names of three references to gcrump@usc.edu.
Germ Layer Differentiation in Zebrafish
A postdoctoral position is available in the Vertebrate Embryology Section of the National Human Genome Research Institute to investigate transcription factor regulatory networks underlying germ layer specification in zebrafish. The laboratory has identified numerous uncharacterized genes expressed in newly-specified germ layer cells (the mesendoderm; see: PNAS 105, 12337-42, 2008). The project will involve delineating targets and activators among transcription factors co-expressed in the mesendoderm.
The successful candidate must be self-motivated to work independently. Experience modifying DNA vectors and working with an animal model is essential. Familiarity with bioinformatics, biochemistry, and microscopy is also desirable. The salary is highly competitive and will be commensurate with experience. Applicants must have a Ph.D. in the biosciences and/or an M.D. awarded within the past 4 years.
To apply, send a CV, cover letter, and the names and telephone numbers of three references by e-mail to: bfeldman@mail.nih.gov
Benjamin Feldman
Vertebrate Embryology Section
NHGRI, NIH
Building 35, Room 1B-205
9000 Rockville Pike
Bethesda, MD 20892
DHHS and NIH are Equal Opportunity Employers.
The NIH is dedicated to building a diverse community in its training and employment programs.
A PhD student position is available in the laboratory of Dr Martin Lowe within the Faculty of Life Sciences, University of Manchester, UK. This position, which is funded by the UK Lowe Syndrome Trust, is available for 3 years starting in September 2009. The successful applicant will join the Faculty Graduate Training Programme, encompassing both lab-based research and accompanying training courses.
The project is to utilize zebrafish as a model organism to investigate the molecular mechanisms underlying Lowe syndrome, an X-linked disorder affecting the brain, kidneys and eyes. Techniques will include embryo injections, in situ hybridization, high resolution confocal microscopy, biochemical techniques such as western blotting and immunoprecipitation, and molecular biology techniques including molecular cloning, genomic and RT-PCR, and in vitro transcription.
The position is open to UK and EU nationals. Candidates require a first or upper second class Honours BSc degree or equivalent, and be fluent in both written and verbal English. We are looking for candidates that are highly motivated with a keen interest in developmental and/or cell biology. Six to 12 months laboratory experience is desirable but not essential.
Pease send a cover letter and CV with the names of 2 referees to martin.lowe@manchester.ac.uk. Applications will accepted until the position is filled.
Post-doctoral position in neuroscience (Biopolis, Singapore)
Our work focuses on fear, using alarm pheromone induced responses in the zebrafish as a paradigm. If you have a strong background in molecular genetics, physiology and/or imaging, and are interested in a multidisciplinary project to understand neural circuits underlying emotion in a vertebrate, please contact:
Suresh Jesuthasan (suresh.jesuthasan@nrp.a-star.edu.sg)
Biomedical Sciences Institutes
Neuroscience Research Partnership
04-13B Proteos
61 Biopolis Drive
Singapore 138673
Tel: +65 64070390
The lab, a part of the A*Star-Duke/NUS Neuroscience Research Partnership, is located in Biopolis, Singapore. This provides state-of-the-art facilities in a stimulating, collegial environment.
Technical Assistant II/Technical Associate I - Whitehead Institute - Sive Lab
Whitehead Institute for Biomedical Research is a leading, nonprofit research and educational institution that has defined the cutting edge of biomedical science, creating a legacy of research excellence and academic eminence since 1982. Wholly independent in its governance, finances and research programs, Whitehead shares a teaching affiliation with Massachusetts Institute of Technology (MIT), offering the intellectual, collegial and scientific benefits of a leading research university. Whitehead's Faculty Members and Fellows run pioneering programs in cancer research, immunology, developmental biology, stem cell research, regenerative medicine, genetics and genomics programs with a record of success. Director David C. Page likens the Institute to an artists' colony. "What we do here at Whitehead is attract the best possible intellectual capital and empower maximally creative - really wildly creative - individuals to realize their dreams within these walls". Whitehead offers a generous comprehensive benefits package which includes health and dental plans, retirement program, paid time off, reimbursement accounts (FSAs), short and long term disability and much more.
Overall Summary
Manage Xenopus laevis and Xenopus tropicalis facilities, contributing to biomedical research focusing on brain and craniofacial development, approximately 50% time. Remaining effort will contribute to original research in the laboratory. Will work under supervision of the laboratory head, Prof. Hazel Sive.
Job Description
Will focus on growth and maintenance of X. tropicalis and X. laevis, encompassing: feeding frogs, raising embryos, monitoring frog health, maintaining water quality, maintaining tanks and equipment, making up relevant solutions.
Perform experimental manipulation of frogs to produce eggs for in vitro fertilization.
Generates and develops concepts and conducts research projects.
Supervise Animal Care Technician.
Qualifications
Advanced degree in biology and 5+ years of experience in a research laboratory. Appropriate for a candidate with a PhD.
A minimum of two years experience working with Xenopus or zebrafish in a research setting is essential.
Self-motivated, organized and efficient person who enjoys working with animals.
Good communication skills essential.
Ability to lift 40lbs of weight
Work schedule includes one weekend day.
Some supervisory/management experience preferred.
Must possess demonstrated ability and knowledge to design and conduct research independently.
Strong instrumentation skills, a high degree of independence, a strong work ethic and ability to work well as part of a team.
Interested candidates should send resume to:
resumes@wi.mit.edu
9 Cambridge Center
Cambridge, MA 02142
We are looking for a motivated PhD student candidate to join our lab in the Institute of Neuroscience at the Technical University Munich, Germany (http://www.misgeld-lab.me.tum.de/new/).
The candidate will have the opportunity to apply for the 3-year PhD graduate program "Medical life science and technology" where the student's project will be complemented by interdisciplinary lectures, seminars and practical courses, all conducted in English.
The PhD project will involve examining axon transport in sensory neurons of zebrafish during development and disease. Techniques used will include the generation of transgenic fish to fluorescently label intracellular organelles and high resolution time-lapse imaging in vivo using wide-field, confocal or two photon microscopy.
We expect that the candidate will have a degree (Masters, Diploma or equivalent) in biology, biochemistry or a related field with at least 9-12 months experience working in a lab. A strong background in neuroscience, molecular biology or cell biology is welcome. In addition, good communication skills, fluency in English and a willingness to learn new techniques are important.
Please send an introductory letter, CV and the names of at least 2 referees and their contact information to Leanne.Godinho@lrz.tum.de and Thomas.Misgeld@lrz.tum.de.
Start date for the position is August 2009 or later. Applications will be accepted until the position is filled.
A postdoctoral position is available at the University of California San Francisco (UCSF) to study the role of regulatory sequences in human biology and disease. Through a combination of comparative genomic strategies, regulatory element analysis, human patient samples, and mouse and fish genetic engineering technologies, we are working to elucidate mechanisms whereby genetic variation within these sequences lead to changes in human phenotypes (more info can be found at http://bts.ucsf.edu/ahituv/) . Preference will be given to individuals with zebrafish related experience and computational background, though this is not a necessity. Please send applications by e-mail to:
Nadav Ahituv
Department of Bioengineering and Therapeutic Sciences
Institute for Human Genetics
UCSF
513 Parnassus Ave.
San Francisco, CA 94143
E-Mail: nadav.ahituv@ucsf.edu
UCSF is an affirmative action/equal opportunity employer. The University undertakes affirmative action to assure equal employment opportunity for underutilized minorities and women, for persons with disabilities, and for covered veterans.
Employer:
Yale University. New Haven, CT.
The Giraldez Lab, works on zebrafish and microRNAs.
http://www.yale.edu/giraldezlab
Job description
Provide research assistance for a zebrafish genetics lab and aid with the maintenance of a freshwater tropical fish (zebrafish) facility under the supervision of the principal investigator of the laboratory. The focus of the overall project is to use zebrafish as a model system to study vertebrate development
Essential Duties of the Position
1. Feed fish, check and maintain water quality.
2. Breed fish and raise young.
3. Maintain tank and equipment.
4. Make up solutions, prepare fish food; limited laboratory maintenance.
5. Preferred: Experience in areas of molecular biology such as DNA cloning, PCR, tissue culture and microinjection.
Education and Training
1. Required: Bachelor's degree in marine Biology, related field of Biology/Molecular biology, or two years of experience working in marine laboratories or molecular biology laboratories.
Skills and Abilities
1. Hands on experience in molecular biology; strong instrumentation skills.
2. High degree in independence, highly motivated, enthusiastic and strong work ethic.
3. Must be self-motivated and physically capable of maintaining 10-liter fish tanks in shelving units.
4. Must not mind working at 26-28 degrees Celsius (82-85 degrees Fahrenheit).
5. Must be able to work as part of a team and work effectively with diverse personalities.
6. Must not keep fish or other fresh water animals at home.
Requirements:
The applicant must be a US national or legal resident of the US.
Additional information
http://www.yale.edu/giraldezlab
Where to send the applications:
Please send short description of your work experience including work with fish and molecular biology, contact information, CV and references in a single word or pdf document to:
Any application missing any of the above information will not be considered.
Review of the applications will begin on may 20th and will continue until a suitable candidate is identified
The Clinical Neurocardiology Section (CNCS), an Independent Section in the Division of Intramural Research of the National Institute of Neurological Disorders and Stroke (NINDS), has a position open for a post-doctoral, preclinical researcher. The CNCS of the NINDS is located on the Bethesda, Maryland campus of the National Institutes of Health (NIH), in the NIH Clinical Center.
The research is in the general area of autonomic disorders that involve catecholamine systems and in the specific area of biomarkers and mechanisms of loss of catecholaminergic neurons in Parkinson idsease (PD) and related disorders. Current projects include catecholamines as autotoxins, interactions of catecholamines with alpha-synuclein, and cellular, murine, and zebrafish models of PD, using techniques such as chromaffin cell culture, western blotting, RTPCR, immunohistochemistry, catecholamine neurochemistry, and confocal microscopy.
Please contact:
Dr. David S. Goldstein
Chief, Clinical Neurocardiology Section, NINDS, NIH
Building 10 Room 6N252
10 Center Drive MSC-1620
Bethesda, Maryland 20892-1620
Phone: 301-496-1115
Fax: 301-402-0180
iPhone: 301-675-1110
E-mail: goldsteind@ninds.nih.gov
University of Massachusetts Medical School, Zebrafish Functional Genomics Core Facility Two positions available
Projects Manager
We seek an experienced individual to manage the Zebrafish Functional Genomics Core Facility at the University of Massachusetts Medical School. The applicant will interact with on-campus researchers to plan and execute core facility services. These will include fish husbandry, mutant and transgenic line maintenance, and microinjections (Morpholino, mRNA, etc.). This work will also include employing cutting-edge technologies for genomic manipulation, such as the use of zinc finger nucleases for targeted reverse genetic approaches. Basic phenotypic analysis will also be performed as necessary. The candidate will take part in performing experiments and supervising a technician as necessary for core projects. The candidate must have experience using the zebrafish as a model system to interrogate gene function, including familiarity and experience with basic bioinformatics approaches for gene identification in zebrafish and relevant reverse genetic strategies. This experience must be documented by publication in peer-reviewed journals. Experience with handling and/or designing databases is highly desirable. Candidate must possess excellent communication and organizational skills. Ideally, the candidate will have a Ph.D. in the biological sciences or related area. Salary will be commensurate with experience.
Technician
We seek an aquatics technician to perform duties related to zebrafish husbandry, transgenic and mutant line maintenance, and embryo manipulation. The candidate will perform microinjection of zebrafish embryos and will assist the Projects manager in executing other core facility services as necessary. Experience with handling zebrafish or other fish species is desirable, but not essential. Experience with basic molecular biology techniques would be ideal. Candidate must be highly organized and detail-oriented. An undergraduate degree (B.S./B.A.) in the biological sciences or related area is required.
If interested in either of the positions above, please email your CV to the contact information below. Selected applicants will be contacted for reference letters and subsequent interviews.
Nathan D. Lawson, PhD
Associate Professor
Program in Gene Function and Expression
University of Massachusetts Medical School
Lazare Research Building, Room 617
364 Plantation Street
Worcester, MA 01605
e-mail: nathan.lawson@umassmed.edu
url: http://lawsonlab.umassmed.edu
A postdoctoral position is available in Dr. Sumanas laboratory at Cincinnati Children's Hospital Medical Center to study molecular mechanisms of cardiovascular development in a zebrafish model system. We are a young growing laboratory with interest in basic mechanisms that control specification, migration and differentiation of endothelial and other cardiovascular lineages as well as their relationship to human vascular diseases. Excellent research environment, competitive salaries and possibilities for interaction with basic researchers and clinicians are available. Please see http://www.cincinnatichildrens.org/research/div/dev-biology/fac-labs/sumanas for more information.
A successful applicant should have or be close to obtaining Ph.D. and a background in developmental or molecular biology. Zebrafish research experience is prefered but not required. Please E-mail a CV and contact information for three references to:
Saulius Sumanas, Ph.D.
Assistant Professor
Division of Developmental Biology, ML7007
Cincinnati Children's Hospital Medical Center
3333 Burnet Ave., S-3,206
Cincinnati, OH 45229
Tel.: 513-803-0435
E-mail: saulius.sumanas@cchmc.org
An NIH-funded postdoctoral position in the Department of Biological Sciences, The University of Pittsburgh, is available immediately to study vascular development using the zebrafish as a model system. Our laboratory employs a diverse array of molecular, biochemical, imaging, and embryological techniques to elucidate genetic pathways that control vascular development. Specifically, we are interested in the role of the TGF-beta type I receptor, ALK1, in vascular development and disease. ALK1 function is critical in vascular development and homeostasis: homozygous ALK1 mutations are embryonic lethal, whereas the heterozygous condition results in the autosomal dominant vascular dysplasia, Hereditary Hemorrhagic Telangiectasia Type 2 (HHT2). Our laboratory is interested in investigating the regulation of alk1 expression; identifying downstream targets of Alk1 activation; and probing the cellular role of Alk1 within the endothelium.
Our department is home to an interactive group of Developmental Biologists studying a variety of developmental processes in zebrafish, Drosophila, mouse, and C. elegans. Our laboratory is also part of an active and growing zebrafish community on the University of Pittsburgh campus, as well as the campus-wide Center for Vascular Remodeling and Regeneration.
Qualified candidates must have a PhD and less than 3 years post-doctoral experience, and a strong publication record. Developmental Biology and/or molecular biology experience required; expertise in mechanotransduction preferred. Interested candidates should send (1) a brief cover letter summarizing scientific accomplishments and stating future research goals; (2) a full CV; and (3) full contact information for three references to:
Dr. Beth Roman
romanb@pitt.edu
Incomplete applications will not be considered.
For more information about our research, please see: http://www.pitt.edu/~biohome/Dept/Frame/Faculty/roman.htm
We are inviting qualified candidates to apply for a Research Technician position at the Torres-Vazquez lab (http://saturn.med.nyu.edu/research/dg/torreslab/). The goal of the lab is to understand the genetic programs and endothelial cell behaviors responsible for assembling the vasculature using the zebrafish.
The ideal candidate for this position is a recent graduate (less than 3 years) with a college or Master's degree in biological sciences, a strong record of scholarly accomplishment, excellent work ethics and strong self-motivation. Research lab experience (developmental genetics, cell biology, molecular biology, confocal imaging and/or biochemistry) and/or publications are not required but are a strong plus. Verbal and written mastery of the English language are essential. This position is particularly well suited for bright individuals interested in obtaining laboratory research experience for 1-2 years before joining a PhD research program.
THE APPLICATION DEADLINE IS MONDAY, APRIL 13-2009.
To apply please send an e-mail to Dr. Jesus Torres-Vazquez at torres@saturn.med.nyu.edu with the subject line "Research Tech application" followed by your name and a single attachment (word document or PDF file) containing:
a) Cover letter (one page) with the following four sections:
a1. Applicant's contact information
- Name, telephone, e-mail and current full address of residence
a2. Scholarly and scientific accomplishments (if applicable)
- Include GPA and relevant awards
a3. Future goals
a4. Expected date of availability
- Candidates available within the next 4 months will be given priority
b) CV with bibliography (if applicable)
- Include a summary of technical skills (if applicable)
- Do not attach PDFs of publications
c) The name, e-mail, telephone number and address of three references
Postdoctoral positions are available at Tufts University Medical School, Boston, to study human craniofacial and tooth development and regeneration using the zebrafish model. The focus of the laboratory is to elucidate molecular mechanisms regulating normal and abnormal craniofacial and tooth development and regeneration, for the eventual development of clinically relevant repair therapies in humans. Ongoing zebrafish projects include an ongoing large-scale mutagenesis screen for novel mineralized tissue mutants, and characterizations of already identified craniofacial and replacement tooth mutants. A large, newly renovated, laboratory in the Tufts Medical School contains state of the art microscopy, microinjection, and histological analysis capabilities, and a new 2,000 tank zebrafish facility. Extensive core facilities are available in the Tufts Medical and Sackler Graduate Schools. Successful candidates must have or be close to obtaining a Ph.D. degree, and a strong background in molecular biology and/or genetics. A knowledge of genetic, molecular, microarray and proteomics technologies, and zebrafish husbandry are desirable. The successful applicant must be able to work well with others, and independently and productively, and exhibit proficiency in writing articles for peer-reviewed journals, and grants.
Please submit current curriculum vitae, a statement of research experience, and complete contact information for three references to:
Pamela. C. Yelick, Ph.D.
Professor and Director, Division of Craniofacial and Molecular Genetics
Department of Oral and Maxillofacial Pathology
Tufts University
136 Harrison Avenue, Room M824
Boston, MA 02111
Phone: 617-636-2430
Fax: 617-636-2432
pamela.yelick@tufts.edu
SCIENTIFIC TECHNICIAN POSITION AT FOX CHASE CANCER CENTER, 333 Cottman Avenue, Philadelphia, PA 19111
Requisition #09-0035
ZEBRA FISH FACILITY
FULL TIME (MAY INCLUDE WEEKENDS)
We are looking for a core animal facility technician to facilitate zebrafish research in multiple laboratories. The primary responsibilities will be to facilitate zebrafish research for multiple laboratories, and care and maintenance of the core zebrafish facility as necessary. Duties will be to act as a liaison for labs undertaking zebrafish projects and design and perform experiments as requested. Experiments will likely include morpholino knockdown, genetic screening, engineering transgenic animals, and the development of assays and analytical tools.
B.S. degree in biology or a related field is preferred, but may be substituted by relevant work experience. Candidates with prior experience rearing zebrafish and performing microinjection, whole mount RNA in situ hybridization, cryosectioning, PCR and DNA cloning are preferred. Candidates should have experience in molecular biology techniques, a background in zebrafish embryology, and the ability to work independently. Applicants are expected have a high level of organizational and communication skills. Local applicants are preferred as interview transportation and relocation is not the responsibility of Fox Chase Cancer Center.
To apply, visit our website http://www.fccc.edu and submit on-line application directly to Requisition #09-0035.
A postdoctoral position is available immediately in the laboratory of Dr. Matthias Hammerschmidt at the Institute for Developmental Biology, University of Cologne, Germany. The project is part of the Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), and deals with the formation and function of the hypothalamic-hypophyseal axis, with particular focus on the neuroendocrine control of feeding behavior, energy homeostasis, obesity and somatic growth, using the zebrafish as a model organism.
Studies include the generation of transgenic lines for in vivo imaging of the plasticity within the hypothalamic melanocortin system in wild-type and mutant fish under different physiological conditions, as well as mutant screens after chemical and insertional mutagenesis.
Applications are invited from candidates who have a background in developmental, cellular and/or molecular biology, or in endocrinology. Please send your application, together with your CV and a list of referees, preferably via email, to:
Matthias Hammerschmidt
Institute for Developmental Biology
Cologne University
Gyrhofstrasse 17
D-50931 Cologne
Email: mhammers@uni-koeln.de
If you need further information, please feel free to email or call me under ++49(0) 221 470 5665
Our lab is interested in the functional characterization of receptors of the LDL receptor gene family (LRPs). In particular, we are studying the role played by these receptors in signaling pathways during vertebrate development (Hammes et al., Cell 122: 751-762; Spoelgen et al., Development 132: 405-414; Willnow et al., Development 134: 3239-3249)
We are seeking applications from talented and highly motivated individuals at the postdoctoral level to carry out studies into the relevance of these receptor pathways for formation of the CNS in zebrafish models. Successful applicants have a profound knowledge in cell and developmental biology with particular emphasis on the zebrafish as model organism.
For further information please contact Thomas Willnow (willnow@mdc-berlin.de).
Available in the Lab of Prof. Vincent Laudet at the Institute of Functional Genomics of Lyon (IGFL) at Ecole Normale Superieure de Lyon (France)
We are using zebrafish to study the role of nuclear receptors during embryonic development and we have recently determined the expression patterns of all NR genes during zebrafish development. We are now specifically interested in the developmental effects of endocrine disruptors such as bisphenol A or genistein. The recruited post-doc will develop zebrafish reporter transgenic lines that will be use to better understand the tissue-specific effects of these compounds. In addition he/she will use pharmacological and genetic methods to identify the molecular targets of these compounds.
Applications are invited from candidates who have a background in developmental biology. Candidates with a personal experience using the zebrafish, other fish models or xenopus will be particularly qualified. The funding is available for 24 months. The candidate should not be of French nationality.
Applicants should send a letter and curriculum vitae, as well as a list of three references, to:
Vincent Laudet
UMR 5242 du CNRS
Institut de Genomique Fonctionnelle de Lyon
ENS de Lyon
46, allee d'Italie
69364 Lyon Cedex 07, France
Tel: 33 (0)4 72 72 81 90
Fax: 33 (0)4 72 72 89 92
E-mail: Vincent.Laudet@ens-lyon.fr
Selected Publications from the Lab:
Bardet P.L. et al. (2005). The ERRalpha orphan nuclear receptor controls morphogenetic movements during zebrafish gastrulation. Dev. Biol. 281:102-11.
Escriva H. et al. (2006). Neofunctionalization in vertebrates: the example of retinoic acid receptors. PLoS Genet. 2:e102.
Bertrand S. et al. (2007). Unexpected Novel Relational Links Uncovered by Extensive Developmental Profiling of Nuclear Receptor Expression. Plos Genet. 3:e188
Nishio SI et al., (2007). Otx5 regulates pineal expression of the zebrafish Rev-erba through a new DNA binding site. Molecular Endocrinology, 22:23-32
Nishio SI et al., (2008) Adiponectin and adiponectin receptor genes are coexpressed during zebrafish embryogenesis and regulated by food deprivation. Developmental Dynamics, 237:1682-1690.
Paris M et al., (2008) Amphioxus postembryonic development reveals the homology of chordate
metamorphosis. Current Biology, 18, 825-830.
A research technician position is offered at the Brain and Mind Research Institute at the University of Sydney in an interactive, young and international team pushing towards the elucidation of neurological diseases using zebrafish as a model system in vertebrate genomics.
The candidate should have finished an education at a biotechnology or medical technology school or should hold a bachelor degree in biology or a comparable field. Knowlege and practical skills in molecular biological lab work and/or histology are required. The work includes work with adult zebrafish and larvae, DNA cloning and tissue staining techniques. Preferred starting date: July 2009.
Please send an introductory letter and a CV to Thomas Becker at tsbecker@med.usyd.edu.au.
A postdoctoral research position is available at The Brain and Mind Research Institute at the University of Sydney for an ambitious and responsible scientist who is committed to research. We are an interactive, young and international team pushing towards the elucidation of neurological diseases using zebrafish as a model system in vertebrate genomics. The project is based on comparative genome analyses, high throughput testing of enhancer sequences in zebrafish and subsequent expression analysis of the transgenes.
The project is part of an EU consortium Project of several groups interacting with each other with the goal to identify genes implicated neurological diseases for studying their cis-regulation. The candidate scientist should be therefore an interactive person with communication and writing skills and should be able to work in a team. We are seeking somebody who is not sparing any effort, who likes to work hard and fast and who would like to learn as much as possible. Experience in developmental genetics and neurobiology is required, and preferably the candidate has skills in transgenic technologies, histology, imaging and bioinformatics. Good English skills are essential. Preferred starting date: July 2009.
Please send applications per email as a single PDF file including a signed introductory letter in which the candidate points our his/her goals, a full CV, a list of publications and the names of two references to Thomas Becker at tsbecker@med.usyd.edu.au.
Postdoctoral Research Positions in Neuronal Regeneration
Department of Biological Sciences and Center for Zebrafish Research University of Notre Dame
Two open postdoctoral research positions are available at any time in the next 6 months to study regeneration of the light-damaged zebrafish retina (Vihtelic and Hyde (2000) J. Neurobiol. 44: 289-307). We are interested in identifying molecular signals that induce and regulate the regeneration response and the signals that guide the neuronal progenitor cells only to the damaged retinal layer. We use a variety of techniques to approach these questions, including gene microarrays to identify candidate genes involved at specific stages of regeneration (Kassen et al. (2007) Dev. Neurobiol. 67: 1009-1031) and electroporation of morpholinos to conditionally knockdown specific proteins in the regenerating adult retina to test the functional significance of candidate proteins (Thummel et al. (2008) Dev. Neurobiol. 68: 392-408).
We are looking for talented individuals who are experienced in a wide variety of fields. More experienced individuals may be considered to be hired at the non-tenure track Research Assistant Professor level. The positions are funded by both NIH grants and a large annual budget provided by the University. Opportunities also exist for the successful candidate to gain some teaching experience, if desired.
Interested candidates should Email a cv and description of their previous research experience to Dr. David Hyde (dhyde@nd.edu). Candidates should also arrange three letters of recommendation to be Emailed directly to David Hyde.
For further information, please contact Dr. David Hyde (dhyde@nd.edu or 574-631-8054) or visit our website at http://www.nd.edu/~hydelab
A postdoctoral position is available immediately for analyzing the impact of endocrine disrupting chemicals on the hypothalamus using transgenic zebrafish. We are a zebrafish research group at Sdertorn University/Karolinska Institute in Huddinge Sweden (South Stockholm) working on development and function of the neuroendocrine hypothalamus in zebrafish. Projects are focused on the genetic analysis of differentiation pathways of neuroendocrine hypothalamic cell lineages. The South Stockholm campus includes the Karolinska Institute, Karolinska Hospital and Sodertorn University. Our department includes research groups working with zebrafish, Drosophila melanogaster, C. elegans and yeast.
The candidate should be experienced in molecular biology methods and have a strong background in Neuro-, Developmental or Cell Biology. Experience with zebrafish is desirable but not a prerequisite. We will continue to review applications until the position is filled. Please send a CV, publication list, statement of research experience and interests, and contact details of two referees to Giselbert Hauptmann (giselbert.hauptmann@ki.se).
Postdoctoral position available at Harvard Medical School and Brigham and Women's Hospital, Boston for work in Zebrafish Cytogenetics. The focus of the laboratory is to understand the structure of vertebrate genomes and its implications in diseases and development (http://www.chromosome.bwh.harvard.edu). Ongoing zebrafish projects in the laboratory use array comparative genomic hybridization, DNA sequencing, RT-PCR and fluorescent in situ hybridization techniques, among others, to analyze structural genomic variation. Individuals must have or be close to obtaining a Ph.D. degree. The candidate must have a strong background in molecular biology and/or genetics. A knowledge of genetic and microarray technologies and zebrafish husbandry are desirable. The successful applicant should be able to demonstrate research productivity and article-writing proficiency for international, peer-reviewed journals. The successful applicant must demonstrate research productivity and writing proficiency through the publication of articles in international, peer-reviewed journals.
Please submit current curriculum vitae, a statement of research experience and names of three individuals who can provide letters of reference to:
Dr. Kim Brown
Department of Pathology
Brigham and Women's Hospital
221 Longwood Avenue
EBRC-404
Boston MA 02115
U.S.A.
email: khbrown@partners.org
Position Description The Department of Biological Sciences at North Dakota State University has a 9-month, tenure-track faculty position in Physiological Genomics at the rank of Assistant Professor, available fall 2009 (16 August 2009). The position is 40% teaching, 50% research, and 10% service. The successful candidate is expected to develop an externally-funded dynamic research program that complements existing strengths in the department and to supervise M.S. and Ph.D. students. Teaching duties include 1 course per semester and advisement of undergraduate and graduate students. The position will be highly competitive with regard to start-up funds, space, and salary.
Minimum Candidates must have 1) a Ph.D. degree from an accredited institution in a discipline appropriate to physiological genomics; 2) relevant postdoctoral experience, 3) demonstrated research experience using system-wide approaches in comparative animal models that link genes and pathways to physiological processes that compliment existing strengths in the department (e.g., metabolism, growth, and reproduction) and evidence of peer-reviewed publication; 4) strong potential to develop an externally-funded research program; 5) evidence of ability to teach at the undergraduate and graduate levels; 6) strong oral, written, and interpersonal communication skills, including demonstrated ability to work/collaborate with others.
Preferred Preference will be given to candidates with 1) an application of their research program to environmental adaptation and 2) demonstrated ability in obtaining extramural funding.
Application Apply for this position through NDSU's online application system at: jobs.ndsu.edu/applicants/Central?quickFind=50741 Applicants should complete an online application and submit the following items 1) a letter of application, 2) a curriculum vitae, 3) a description of research interests (2 pages maximum), 4) a statement of teaching interests and philosophy (2 pages maximum), and 5) reprints of a maximum of three representative publications. Only online applications will be accepted.
For questions regarding this position, feel free to contact the Physiological Genomicist Search Committee at ndsu.biological.sciences@ndsu.edu.
Review of applications will begin February 15, 2009, and continue until a suitable applicant pool has been established.
NDSU is an equal opportunity employer committed to excellence through diversity and has an active career partner program.
Position Description The Department of Biological Sciences at North Dakota State University has a 9-month, tenure-track faculty position in evolutionary developmental biology at the rank of Assistant Professor, available fall 2009 (16 August 2009). The position is 40% teaching, 50% research, and 10% service. The successful candidate is expected to develop an externally-funded dynamic research program that complements existing strengths in the department. Teaching duties include 1 course per semester and advisement of undergraduate and graduate students. The position will be highly competitive with regard to start-up funds, space, and salary.
Minimum Candidates must have 1) a Ph.D. degree from an accredited institution in a discipline appropriate to evolutionary/developmental biology; 2) relevant postdoctoral experience, (3) demonstrated research experience in evolutionary/developmental biology that complements existing strengths in the department and evidence of peer-reviewed publication; 4) evidence of ability to develop an externally-funded research program; 5) evidence of ability to teach at the undergraduate and graduate levels; 6) strong oral, written, and interpersonal communication skills, including demonstrated ability to work/collaborate with others.
Preferred Preference will be given to candidates with 1) an application of their research program to evolutionary aspects of developmental biology 2) background in studying genetic and developmental bases to evolutionarily and ecologically important traits; 3) experience with non-model systems.
Application Apply for this position through NDSU's online application system at: jobs.ndsu.edu/applicants/Central?quickFind=50727 Applicants should complete an online application and submit the following items 1) a letter of application, 2) a curriculum vitae, 3) a description of research interests (2 pages maximum), 4) a statement of teaching interests and philosophy (1 page maximum), and 5) reprints of a maximum of three representative publications. Only online applications will be accepted.
For questions regarding this position, feel free to contact the Evolutionary Developmental Biologist Search Committee at ndsu.biological.sciences@ndsu.edu.
Review of applications will begin February 15, 2009, and continue until a suitable applicant pool has been established.
NDSU is an equal opportunity employer committed to excellence through diversity and has an active career partner program.
An NIH-supported Post-doctoral position is available in an established Research Program at Children's Hospital and Harvard Medical School, Boston.
The project addresses the mechanism of cholera toxin entry into host cells. This involves mechanisms of lipid sorting; membrane dynamics; and ER associated degradation (ERAD) of terminally misfolded proteins.
We already have identified 12 mutant fish fully resistant to intoxication.
I am seeking a scientist with strong skills in Genetics, Molecular Biology, Cell Biology, or Protein Biochemistry to join this project, map 3 mutant fish, and study the cell biology of the genes identified.
Experience in Genetics is required. Or strong skills in Cell Biology, Membrane trafficking or Microbial Pathogenesis/Host Defense and an interest in the project.
Relevant publications: Cell Microbiol 10:67-80; J Biol Chem 280:28127-28132;. 5:596-601, 2004; Mol Biol Cell. 15:3631-41, 2004; Mol Biol Cell. 14:4783-93, 2003; Trend Biol Chem. 28:639-645, 2003; Cell 2001,104, 937-948; EMBO Rep 2002 3, 1222-1227; J Cell Biol 1998 141, 917-927.
For further information, please contact: Wayne I. Lencer, MD Professor of Pediatrics, Harvard Medical School and Children's Hospital Boston c/o anneka.werner-gavin@childrens.harvard.edu
Web site: http://www.lencerlab.org (web site is not up to date)
A postdoctoral position is available immediately in the laboratory of Dr. Fang Lin in the Department of Anatomy and Cell Biology, University of Iowa. The laboratory is interested in studying G protein couple receptors and G protein signaling in zebrafish embryogenesis. These studies will employ a combination of genetic, genomic, cellular, and biochemical techniques. A highly motivated Ph.D. with experience in the study of signal transduction, developmental and molecular biology is desired. Previous experience with the zebrafish model is preferable, but not a requirement, as training will be provided.
Iowa City is a very nice, safe and collegial town with high living standards, but inexpensive cost of living as compared to larger cities. Recent survey ranks UI as top University for postdoctoral students
(http://www.news-releases.uiowa.edu/2007/March/030107post-doctorate.html) To apply, please send a CV, statement of research interests, and name & contact details of three referees to:
Dr. Fang Lin
Email: fang-lin@uiowa.edu
The University of Iowa is an Affirmative Action/Equal Employment Opportunity Employer. Women and minorities are strongly encouraged to apply.