ZFIN ID: ZDB-GENE-980526-89

CITATIONS (134 total)

Gene Name: smoothened homolog (Drosophila)
Gene Symbol: smo

Publications (14):

Albert, S., Müller, F., Fischer, N., Biellmann, D., Neumann, C., Blader, P., and Strähle, U. (2003) Cyclops-independent floor plate differentiation in zebrafish embryos. Dev. Dyn. 226(1):59-66

Amsterdam, A., Burgess, S., Golling, G., Chen, W., Sun, Z., Townsend, K., Farrington, S., Haldi, M., and Hopkins, N. (1999) A large-scale insertional mutagenesis screen in zebrafish. Genes Dev. 13(20):2713-2724

Barresi, M.J., Stickney, H.L., and Devoto, S.H. (2000) The zebrafish slow-muscle-omitted gene product is required for Hedgehog signal transduction and the development of slow muscle identity. Development 127(10):2189-2199

Bergeron, S.A., Milla, L.A., Villegas, R., Shen, M.C., Burgess, S.M., Allende, M.L., Karlstrom, R.O., and Palma, V. (2008) Expression profiling identifies novel Hh/Gli-regulated genes in developing zebrafish embryos. Genomics 91(2):165-177

Bisgrove, B.W., Snarr, B.S., Emrazian, A., and Yost, H.J. (2005) Polaris and Polycystin-2 in dorsal forerunner cells and Kupffer's vesicle are required for specification of the zebrafish left-right axis. Dev. Biol. 287(2):274-288

Böhm, S., Jin, H., Hughes, S.M., Roberts, R.G., and Hinits, Y. (2008) Dystrobrevin and dystrophin family gene expression in zebrafish. Gene Expr. Patterns 8(2):71-78

Cheesman, S.E., and Eisen, J.S. (2004) gsh1 demarcates hypothalamus and intermediate spinal cord in zebrafish. Gene Expr. Patterns 5(1):107-112

Cheesman, S.E., Layden, M.J., Von Ohlen, T., Doe, C.Q., and Eisen, J.S. (2004) Zebrafish and fly Nkx6 proteins have similar CNS expression patterns and regulate motoneuron formation. Development 131(21):5221-5232

Chen, W., Burgess, S., and Hopkins, N. (2001) Analysis of the zebrafish smoothened mutant reveals conserved and divergent functions of hedgehog activity. Development 128(12):2385-2396

Chung, W.S., and Stainier, D.Y. (2008) Intra-endodermal interactions are required for pancreatic beta cell induction. Dev. Cell 14(4):582-593

Chung, W.S., Shin, C.H., and Stainier, D.Y. (2008) Bmp2 signaling regulates the hepatic versus pancreatic fate decision. Dev. Cell 15(5):738-748

Corbit, K.C., Aanstad, P., Singla, V., Norman, A.R., Stainier, D.Y., and Reiter, J.F. (2005) Vertebrate Smoothened functions at the primary cilium. Nature 437(7061):1018-1021

Culverwell, J. and Karlstrom, R.O. (2002) Making the connection: retinal axon guidance in the zebrafish. Sem. Cell Dev. Biol. 13(6):497-506

Cunliffe, V.T. (2004) Histone deacetylase 1 is required to repress Notch target gene expression during zebrafish neurogenesis and to maintain the production of motoneurones in response to hedgehog signalling. Development 131(12):2983-2995

Cunliffe, V.T., and Casaccia-Bonnefil, P. (2006) Histone deacetylase 1 is essential for oligodendrocyte specification in the zebrafish CNS. Mech. Dev. 123(1):24-30

David, N.B., Sapede, D., Saint-Etienne, L., Thisse, C., Thisse, B., Dambly-Chaudiere, C., Rosa, F.M., and Ghysen, A. (2002) Molecular basis of cell migration in the fish lateral line: role of the chemokine receptor CXCR4 and of its ligand, SDF1. Proc. Natl. Acad. Sci. USA 99(25):16297-16302

diIorio, P.J., Moss, J.B., Sbrogna, J.L., Karlstrom, R.O., and Moss, L.G. (2002) Sonic hedgehog is required early in pancreatic islet development.. Dev. Biol. 244(1):75-84

Du, S.J., Rotllant, J., and Tan, X. (2006) Muscle-specific expression of the smyd1 gene is controlled by its 5.3-kb promoter and 5'-flanking sequence in zebrafish embryos. Dev. Dyn. 235(12):3306-3315

Dutta, S., Dietrich, J.E., Aspock, G., Burdine, R.D., Schier, A., Westerfield, M., and Varga, Z.M. (2005) pitx3 defines an equivalence domain for lens and anterior pituitary placode. Development 132(7):1579-1590

Dutton, K., Abbas, L., Spencer, J., Brannon, C., Mowbray, C., Nikaido, M., Kelsh, R.N., and Whitfield, T.T. (2009) A zebrafish model for Waardenburg syndrome type IV reveals diverse roles for Sox10 in the otic vesicle. Dis. Model. Mech. 2(1-2):68-83

Elworthy, S., Hargrave, M., Knight, R., Mebus, K., and Ingham, P.W. (2008) Expression of multiple slow myosin heavy chain genes reveals a diversity of zebrafish slow twitch muscle fibres with differing requirements for Hedgehog and Prdm1 activity. Development 135(12):2115-2126

Feijóo, C.G., Sarrazin, A.F., Allende, M.L., and Glavic, A. (2009) Cystein-serine-rich nuclear protein 1, Axud1/Csrnp1, is essential for cephalic neural progenitor proliferation and survival in zebrafish. Dev. Dyn. 238(8):2034-2043

Feng, X., Adiarte, E.G., and Devoto, S.H. (2006) Hedgehog acts directly on the zebrafish dermomyotome to promote myogenic differentiation. Dev. Biol. 300(2):736-746

Filippi, A., Tiso, N., Deflorian, G., Zecchin, E., Bortolussi, M., and Argenton, F. (2005) The basic helix-loop-helix olig3 establishes the neural plate boundary of the trunk and is necessary for development of the dorsal spinal cord. Proc. Natl. Acad. Sci. USA 102(12):4377-4382

García-Lecea, M., Kondrychyn, I., Fong, S.H., Ye, Z.R., and Korzh, V. (2008) In vivo Analysis of Choroid Plexus Morphogenesis in Zebrafish. PLoS One 3(9):e3090

Gering, M., and Patient, R. (2005) Hedgehog Signaling Is Required for Adult Blood Stem Cell Formation in Zebrafish Embryos. Dev. Cell 8(3):389-400

Golling, G., Amsterdam, A., Sun, Z., Antonelli, M., Maldonado, E., Chen, W., Burgess, S., Haldi, M., Artzt, K., Farrington, S., Lin, S.Y., Nissen, R.M., and Hopkins, N. (2002) Insertional mutagenesis in zebrafish rapidly identifies genes essential for early vertebrate development. Nat. Genet. 31(2):135-140

Guner, B., and Karlstrom, R.O. (2007) Cloning of zebrafish nkx6.2 and a comprehensive analysis of the conserved transcriptional response to Hedgehog/Gli signaling in the zebrafish neural tube. Gene Expr. Patterns 7(5):596-605

Hadzhiev, Y., Lele, Z., Schindler, S., Wilson, S.W., Ahlberg, P., Straehle, U., and Mueller, F. (2007) Hedgehog signaling patterns the outgrowth of unpaired skeletal appendages in zebrafish. BMC Dev. Biol. 7(1):75

Hamade, A., Deries, M., Begemann, G., Bally-Cuif, L., Genet, C., Sabatier, F., Bonnieu, A., and Cousin, X. (2006) Retinoic acid activates myogenesis in vivo through Fgf8 signalling. Dev. Biol. 289(1):127-140

Hammond, C.L., Hinits, Y., Osborn, D.P., Minchin, J.E., Tettamanti, G., and Hughes, S.M. (2007) Signals and myogenic regulatory factors restrict pax3 and pax7 expression to dermomyotome-like tissue in zebrafish. Dev. Biol. 302(2):504-521

Hammond, K.L., Baxendale, S., McCauley, D.W., Ingham, P.W., and Whitfield, T.T. (2009) Expression of patched, prdm1 and engrailed in the lamprey somite reveals conserved responses to Hedgehog signaling. Evol. Dev. 11(1):27-40

Hammond, K.L., Loynes, H.E., Folarin, A.A., Smith, J., and Whitfield, T.T. (2003) Hedgehog signalling is required for correct anteroposterior patterning of the zebrafish otic vesicle. Development 130(7):1403-1417

Henry, C.A., and Amacher, S.L. (2004) Zebrafish slow muscle cell migration induces a wave of fast muscle morphogenesis. Dev. Cell 7(6):917-923

Hinits, Y., and Hughes, S.M. (2007) Mef2s are required for thick filament formation in nascent muscle fibres. Development 134(13):2511-2519

Hirsinger, E., Stellabotte, F., Devoto, S.H., and Westerfield, M. (2004) Hedgehog signaling is required for commitment but not initial induction of slow muscle precursors. Dev. Biol. 275(1):143-157

Hollway, G.E., Maule, J., Gautier, P., Evans, T.M., Keenan, D.G., Lohs, C., Fischer, D., Wicking, C., and Currie, P.D. (2006) Scube2 mediates Hedgehog signalling in the zebrafish embryo. Dev. Biol. 294(1):104-118

Holzschuh, J., Hauptmann, G., and Driever, W. (2003) Genetic analysis of the roles of Hh, FGF8, and nodal signaling during catecholaminergic system development in the zebrafish brain. J. Neurosci. 23(13):5507-5519

Honjo, Y., and Eisen, J.S. (2005) Slow muscle regulates the pattern of trunk neural crest migration in zebrafish. Development 132(20):4461-4470

Hsu, H.-J., Lin, G., and Chung, B.-C. (2003) Parallel early development of zebrafish interrenal glands and pronephros: differential control by wt1 and ff1b. Development 130(10):2107-2116

Ingham, P.W., and Kim, H.R. (2005) Hedgehog signalling and the specification of muscle cell identity in the Zebrafish embryo. Exp. Cell Res. 306(2):336-342

Karlstrom, R.O., Tyurina, O.V., Kawakami, A., Nishioka, N., Talbot, W.S., Sasaki, H., and Schier, A.F. (2003) Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development. Development 130(8):1549-1564

Kawakami, A., Nojima, Y., Toyoda, A., Takahoko, M., Satoh, M., Tanaka, H., Wada, H., Masai, I., Terasaki, H., Sakaki, Y., Takeda, H., and Okamoto, H. (2005) The zebrafish-secreted matrix protein you/scube2 is implicated in long-range regulation of hedgehog signaling. Curr. Biol. 15(5):480-488

Kay, J.N., Link, B.A., and Baier, H. (2005) Staggered cell-intrinsic timing of ath5 expression underlies the wave of ganglion cell neurogenesis in the zebrafish retina. Development 132(11):2573-2585

Kazakova, N., Li, H., Mora, A., Jessen, K.R., Mirsky, R., Richardson, W.D., and Smith, H.K. (2006) A screen for mutations in zebrafish that affect myelin gene expression in Schwann cells and oligodendrocytes. Dev. Biol. 297(1):1-13

Ke, Z., Emelyanov, A., Lim, S.E., Korzh, V., and Gong, Z. (2005) Expression of a novel zebrafish zinc finger gene, gli2b, is affected in Hedgehog and Notch signaling related mutants during embryonic development. Dev. Dyn. 232(2):479-486

Ke, Z., Kondrichin, I., Gong, Z., and Korzh, V. (2008) Combined activity of the two Gli2 genes of zebrafish play a major role in Hedgehog signaling during zebrafish neurodevelopment. Mol. Cell. Neurosci. 37(2):388-401

Kishi, S., Bayliss, P.E., Uchiyama, J., Koshimizu, E., Qi, J., Nanjappa, P., Imamura, S., Islam, A., Neuberg, D., Amsterdam, A., and Roberts, T.M. (2008) The identification of zebrafish mutants showing alterations in senescence-associated biomarkers. PLoS Genet. 4(8):e1000152

Knight, R.D., Mebus, K., and Roehl, H.H. (2008) Mandibular arch muscle identity is regulated by a conserved molecular process during vertebrate development. J. Exp. Zoolog. B Mol. Dev. Evol. 310(4):355-369

Lee, B.C., and Roy, S. (2006) Blimp-1 is an essential component of the genetic program controlling development of the pectoral limb bud. Dev. Biol. 300(2):623-634

Lewis, K.E. and Eisen, J.S. (2003) From cells to circuits: development of the zebrafish spinal cord. Prog. Neurobiol. 69(6):419-449

Lewis, K.E. and Eisen, J.S. (2001) Hedgehog signaling is required for primary motoneuron induction in zebrafish. Development 128(18):3485-3495

Lewis, K.E., Bates, J., and Eisen, J.S. (2005) Regulation of iro3 expression in the zebrafish spinal cord. Dev. Dyn. 232(1):140-148

Li, Z., Korzh, V., and Gong, Z. (2007) Localized rbp4 expression in the yolk syncytial layer plays a role in yolk cell extension and early liver development. BMC Dev. Biol. 7(1):117

Liew, H.P., Choksi, S.P., Wong, K.N., and Roy, S. (2008) Specification of vertebrate slow-twitch muscle fiber fate by the transcriptional regulator Blimp1. Dev. Biol. 324(2):226-235

Loucks, E.J., Schwend, T., and Ahlgren, S.C. (2007) Molecular changes associated with teratogen-induced cyclopia. Birth Defects Res. A Clin. Mol. Teratol. 79(9):642-651

López-Schier, H., Starr, C.J., Kappler, J.A., Kollmar, R., and Hudspeth, A.J. (2004) Directional cell migration establishes the axes of planar polarity in the posterior lateral-line organ of the zebrafish. Dev. Cell 7(3):401-412

Mann, C.J., Osborn, D.P., and Hughes, S.M. (2007) Vestigial-like-2b (VITO-1b) and Tead-3a (Tef-5a) expression in zebrafish skeletal muscle, brain and notochord. Gene Expr. Patterns 7(8):827-836

Masai, I., Yamaguchi, M., Tonou-Fujimori, N., Komori, A., and Okamoto, H. (2005) The hedgehog-PKA pathway regulates two distinct steps of the differentiation of retinal ganglion cells: the cell-cycle exit of retinoblasts and their neuronal maturation. Development 132(7):1539-1553

Mathieu, J., Barth, A., Rosa, F.M., Wilson, S.W., and Peyriéras, N. (2002) Distinct and cooperative roles for Nodal and Hedgehog signals during hypothalamic development. Development 129(13):3055-3065

Mavropoulos, A., Devos, N., Biemar, F., Zecchin, E., Argenton, F., Edlund, H., Motte, P., Martial, J.A., and Peers, B. (2005) sox4b is a key player of pancreatic alpha cell differentiation in zebrafish. Dev. Biol. 285(1):211-223

McFarland, K.A., Topczewska, J.M., Weidinger, G., Dorsky, R.I., and Appel, B. (2008) Hh and Wnt signaling regulate formation of olig2(+) neurons in the zebrafish cerebellum. Dev. Biol. 318(1):162-171

Nakano, Y., Kim, H.R., Kawakami, A., Roy, S., Schier, A.F., and Ingham, P.W. (2004) Inactivation of dispatched 1 by the chameleon mutation disrupts Hedgehog signalling in the zebrafish embryo. Dev. Biol. 269(2):381-392

Nicolson, T. (2005) The genetics of hearing and balance in zebrafish. Annu. Rev. Genet. 39:9-22

Ninkovic, J., Stigloher, C., Lillesaar, C., and Bally-Cuif, L. (2008) Gsk3{beta}/PKA and Gli1 regulate the maintenance of neural progenitors at the midbrain-hindbrain boundary in concert with E(Spl) factor activity. Development 135(18):3137-3148

Norton, W.H., Mangoli, M., Lele, Z., Pogoda, H.M., Diamond, B., Mercurio, S., Russell, C., Teraoka, H., Stickney, H.L., Rauch, G.J., Heisenberg, C.P., Houart, C., Schilling, T.F., Frohnhoefer, H.G., Rastegar, S., Neumann, C.J., Gardiner, R.M., Strähle, U., Geisler, R., Rees, M., Talbot, W.S., and Wilson, S.W. (2005) Monorail/Foxa2 regulates floorplate differentiation and specification of oligodendrocytes, serotonergic raphe neurones and cranial motoneurones. Development 132(4):645-658

Ochi, H., Pearson, B.J., Chuang, P.T., Hammerschmidt, M., and Westerfield, M. (2006) Hhip regulates zebrafish muscle development by both sequestering Hedgehog and modulating localization of Smoothened. Dev. Biol. 297(1):127-140

Park, H.-C., Mehta, A., Richardson, J.S., and Appel, B. (2002) olig2 is required for zebrafish primary motor neuron and oligodendrocyte development. Dev. Biol. 248(2):356-368

Park, H.C., Shin, J., and Appel, B. (2004) Spatial and temporal regulation of ventral spinal cord precursor specification by Hedgehog signaling. Development 131(23):5959-5969

Park, S.W., Davison, J.M., Rhee, J., Hruban, R.H., Maitra, A., and Leach, S.D. (2008) Oncogenic KRAS Induces Progenitor Cell Expansion and Malignant Transformation in Zebrafish Exocrine Pancreas. Gastroenterology 134(7):2080-2090

Parkin, C.A., Allen, C.E., and Ingham, P.W. (2009) Hedgehog signalling is required for cloacal development in the zebrafish embryo. Int. J. Dev. Biol. 53(1):45-57

Paulus, J.D., Willer, G.B., Willer, J.R., Gregg, R.G., and Halloran, M.C. (2009) Muscle contractions guide rohon-beard peripheral sensory axons. J. Neurosci. 29(42):13190-13201

Pendeville, H., Winandy, M., Manfroid, I., Nivelles, O., Motte, P., Pasque, V., Peers, B., Struman, I., Martial, J.A., and Voz, M.L. (2008) Zebrafish Sox7 and Sox18 function together to control arterial-venous identity. Dev. Biol. 317(2):405-416

Philipp, M., Fralish, G.B., Meloni, A.R., Chen, W., Macinnes, A., Barak, L.S., and Caron, M.G. (2008) Smoothened Signaling in Vertebrates Is Facilitated by a G-Protein Coupled Receptor Kinase. Mol. Biol. Cell 19(12):5478-5489

Phillips, R.B., Amores, A., Morasch, M.R., Wilson, C., and Postlethwait, J.H. (2006) Assignment of zebrafish genetic linkage groups to chromosomes. Cytogenet. Genome Res. 114(2):155-162

Pinheiro, P., Gering, M., and Patient, R. (2004) The basic helix-loop-helix transcription factor, Tal2, marks the lateral floor plate of the spinal cord in zebrafish. Gene Expr. Patterns 4(1):85-92

Poon, K.L., Richardson, M., and Korzh, V. (2008) Expression of zebrafish nos2b surrounds oral cavity. Dev. Dyn. 237(6):1662-1667

Rastegar, S., Albert, S., Le Roux, I., Fischer, N., Blader, P., Müller, F., and Strähle, U. (2002) A floor plate enhancer of the zebrafish netrin1 gene requires Cyclops (Nodal) signalling and the winged helix transcription factor FoxA2. Dev. Biol. 252(1):1-14

Reichenbach, B., Delalande, J.M., Kolmogorova, E., Prier, A., Nguyen, T., Smith, C.M., Holzschuh, J., and Shepherd, I.T. (2008) Endoderm-derived Sonic hedgehog and mesoderm Hand2 expression are required for enteric nervous system development in zebrafish. Dev. Biol. 318(1):52-64

Robu, M.E., Larson, J.D., Nasevicius, A., Beiraghi, S., Brenner, C., Farber, S.A., and Ekker, S.C. (2007) p53 activation by knockdown technologies. PLoS Genet. 3(5):e78

Rohr, K.B., Barth, K.A., Varga, Z.M., and Wilson, S.W. (2001) The nodal pathway acts upstream of hedgehog signaling to specify ventral telencephalic identity. Neuron 29(2):341-351

Roy, S., Qiao, T., Wolff, C., and Ingham, P.W. (2001) Hedgehog signaling pathway is essential for pancreas specification in the zebrafish embryo. Curr. Biol. 11(17):1358-1363

Ryu, S., Holzschuh, J., Mahler, J., and Driever, W. (2006) Genetic analysis of dopaminergic system development in zebrafish. J. Neural Transm. Suppl. 70:61-66

Sanek, N.A., and Grinblat, Y. (2008) A novel role for zebrafish zic2a during forebrain development. Dev. Biol. 317(1):325-335

Sbrogna, J.L., Barresi, M.J., and Karlstrom, R.O. (2003) Multiple roles for Hedgehog signaling in zebrafish pituitary development. Dev. Biol. 254(1):19-35

Schafer, M., Kinzel, D., and Winkler, C. (2007) Discontinuous organization and specification of the lateral floor plate in zebrafish. Dev. Biol. 301(1):117-129

Schibler, A., and Malicki, J. (2007) A screen for genetic defects of the zebrafish ear. Mech. Dev. 124(7-8):592-604

Scholpp, S., Wolf, O., Brand, M., and Lumsden, A. (2006) Hedgehog signalling from the zona limitans intrathalamica orchestrates patterning of the zebrafish diencephalon. Development 133(5):855-864

Schäfer, M., Kinzel, D., Neuner, C., Schartl, M., Volff, J.N., and Winkler, C. (2005) Hedgehog and retinoid signalling confines nkx2.2b expression to the lateral floor plate of the zebrafish trunk. Mech. Dev. 122(1):43-56

Sheela, S.G., Lee, W.C., Lin, W.W., and Chung, B.C. (2005) Zebrafish ftz-f1a (nuclear receptor 5a2) functions in skeletal muscle organization. Dev. Biol. 286(2):377-390

Siekmann, A.F., and Brand, M. (2005) Distinct tissue-specificity of three zebrafish ext1 genes encoding proteoglycan modifying enzymes and their relationship to somitic Sonic Hedgehog signaling. Dev. Dyn. 232(2):498-505

Snow, C.J., and Henry, C.A. (2009) Dynamic formation of microenvironments at the myotendinous junction correlates with muscle fiber morphogenesis in zebrafish. Gene Expr. Patterns 9(1):37-42

Stenkamp, D.L. and Frey, R.A. (2003) Extraretinal and retinal hedgehog signaling sequentially regulate retinal differentiation in zebrafish. Dev. Biol. 258(2):349-363

Stevens, C.B., and Halloran, M.C. (2005) Developmental expression of sema3G, a novel zebrafish semaphorin. Gene Expr. Patterns 5(5):647-653

Takamiya, M., and Campos-Ortega, J.A. (2006) Hedgehog signalling controls zebrafish neural keel morphogenesis via its level-dependent effects on neurogenesis. Dev. Dyn. 235(4):978-997

Take-uchi, M., Clarke, J.D.W., and Wilson, S.W. (2003) Hedgehog signalling maintains the optic stalk-retinal interface through the regulation of Vax gene activity. Development 130(5):955-968

Tallafuss, A., Adolf, B., and Bally-Cuif, L. (2003) Selective control of neuronal cluster size at the forebrain/midbrain boundary by signaling from the prechordal plate. Dev. Dyn. 227(4):524-535

Tay, S.Y., Ingham, P.W., and Roy, S. (2005) A homologue of the Drosophila kinesin-like protein Costal2 regulates Hedgehog signal transduction in the vertebrate embryo. Development 132(4):625-634

Teraoka, H., Dong, W., Okuhara, Y., Iwasa, H., Shindo, A., Hill, A.J., Kawakami, A., and Hiraga, T. (2006) Impairment of lower jaw growth in developing zebrafish exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin and reduced hedgehog expression. Aquat. Toxicol. 78(2):103-113

Teraoka, H., Russell, C., Regan, J., Chandrasekhar, A., Concha, M.L., Yokoyama, R., Higashi, K., Take-Uchi, M., Dong, W., Hiraga, T., Holder, N., and Wilson, S.W. (2004) Hedgehog and Fgf signaling pathways regulate the development of tphR-expressing serotonergic raphe neurons in zebrafish embryos. J. Neurobiol. 60(3):275-288

Thomas, N.A., Koudijs, M., van Eeden, F.J., Joyner, A.L., and Yelon, D. (2008) Hedgehog signaling plays a cell-autonomous role in maximizing cardiac developmental potential. Development 135(22):3789-3799

Tyurina, O.V., Guner, B., Popova, E., Feng, J., Schier, A.F., Kohtz, J.D., and Karlstrom, R.O. (2005) Zebrafish Gli3 functions as both an activator and a repressor in Hedgehog signaling. Dev. Biol. 277(2):537-556

Ungos, J.M., Karlstrom, R.O., and Raible, D.W. (2003) Hedgehog signaling is directly required for the development of zebrafish dorsal root ganglia neurons. Development 130(22):5351-5362

Vanderlaan, G., Tyurina, O.V., Karlstrom, R.O., and Chandrasekhar, A. (2005) Gli function is essential for motor neuron induction in zebrafish. Dev. Biol. 282(2):550-570

Varga, Z.M., Amores, A., Lewis, K.E., Yan, Y.-L., Postlethwait, J.H., Eisen, J.S., and Westerfield, M. (2001) Zebrafish smoothened functions in ventral neural tube specification and axon tract formation. Development 128(18):3497-3509

Vinothkumar, S., Rastegar, S., Takamiya, M., Ertzer, R., and Strähle, U. (2008) Sequential and cooperative action of Fgfs and Shh in the zebrafish retina. Dev. Biol. 314(1):200-214

von Hofsten, J., Elworthy, S., Gilchrist, M.J., Smith, J.C., Wardle, F.C., and Ingham, P.W. (2008) Prdm1- and Sox6-mediated transcriptional repression specifies muscle fibre type in the zebrafish embryo. EMBO Rep. 9(7):683-689

Wada, N., Javidan, Y., Nelson, S., Carney, T.J., Kelsh, R.N., Schilling, T.F. (2005) Hedgehog signaling is required for cranial neural crest morphogenesis and chondrogenesis at the midline in the zebrafish skull. Development 132(17):3977-3988

Wan, H., Korzh, S., Li, Z., Mudumana, S.P., Korzh, V., Jiang, Y.J., Lin, S., and Gong, Z. (2006) Analyses of pancreas development by generation of gfp transgenic zebrafish using an exocrine pancreas-specific elastaseA gene promoter. Exp. Cell Res. 312(9):1526-1539

Whitfield, T.T. (2002) Zebrafish as a model for hearing and deafness. J. Neurobiol. 53(2):157-171

Wilbanks, A.M., Fralish, G.B., Kirby, M.L., Barak, L.S., Li, Y.X., and Caron, M.G. (2004) Beta-arrestin 2 regulates zebrafish development through the hedgehog signaling pathway. Science. 306(5705):2264-2267

Wilm, T.P., and Solnica-Krezel, L. (2005) Essential roles of a zebrafish prdm1/blimp1 homolog in embryo patterning and organogenesis. Development 132(2):393-404

Wolff, C., Roy, S., and Ingham, P.W. (2003) Multiple muscle cell identities induced by distinct levels and timing of hedgehog activity in the zebrafish embryo. Curr. Biol. 13(14):1169-1181

Woods, I.G., and Talbot, W.S. (2005) The you Gene Encodes an EGF-CUB Protein Essential for Hedgehog Signaling in Zebrafish. PLoS Biol. 3(3):e66

Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome Res. 15(9):1307-1314

Yamaguchi, M., Fujimori-Tonou, N., Yoshimura, Y., Kishi, T., Okamoto, H., and Masai, I. (2008) Mutation of DNA primase causes extensive apoptosis of retinal neurons through the activation of DNA damage checkpoint and tumor suppressor p53. Development 135(7):1247-1257

Yu, X., Ng, C.P., Habacher, H., and Roy, S. (2008) Foxj1 transcription factors are master regulators of the motile ciliogenic program. Nat. Genet. 40(12):1445-1453

Zecchin, E., Mavropoulos, A., Devos, N., Filippi, A., Tiso, N., Meyer, D., Peers, B., Bortolussi, M., Argenton, F. (2004) Evolutionary conserved role of ptf1a in the specification of exocrine pancreatic fates. Dev. Biol. 268(1):174-184

Zeng, L., Carter, A.D., and Childs, S.J. (2009) miR-145 directs intestinal maturation in zebrafish. Proc. Natl. Acad. Sci. USA 106(42):17793-17798

Zilinski, C.A., Shah, R., Lane, M.E., and Jamrich, M. (2005) Modulation of zebrafish pitx3 expression in the primordia of the pituitary, lens, olfactory epithelium and cranial ganglia by hedgehog and nodal signaling. Genesis 41(1):33-40

Additional Citations (15):

Phenotype Annotation (1994-2006) (2006) Mutant Data Curated from Older Literature. ZFIN Historical Data

ZFIN Staff (2003) Computational Sequence to Gene Association in ZFIN. Semi-automated Curation

ZFIN Staff (2003) Curation of BAC ends Database Links. Automated Data Submission

ZFIN Staff (2002) Curation of EMBL records. Automated Data Submission

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission

ZFIN Staff (2002) Curation of Entrez Gene Database Links. Automated Data Submission

ZFIN Staff (2002) Curation of Protein Database Links. Automated Data Submission

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission

ZFIN Staff (2002) Gene Ontology Annotation Through Association of SWISS-PROT Keywords with GO Terms. Automated Data Submission

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation

ZFIN Staff (2003) Submission and Curation of Mutant and Transgenic Lines. ZFIN Direct Data Submission

ZIRC and ZFIN Staff (2007) Mutant and Transgenic Line Submissions. ZFIN Direct Data Submission

ZIRC and ZFIN Staff (2008) Mutant and Transgenic Line Submissions 2008. ZFIN Direct Data Submission

ZIRC and ZFIN Staff (2007) Mutant and Transgenic Line Submissions. ZFIN Direct Data Submission