Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030321-1
CITATIONS (51 total)

Gene Name: GLI-Kruppel family member 1
Gene Symbol: gli1
Publications (6):
Albert, S., Müller, F., Fischer, N., Biellmann, D., Neumann, C., Blader, P., and Strähle, U. (2003) Cyclops-independent floor plate differentiation in zebrafish embryos. Dev. Dyn. 226(1):59-66
Barresi, M.J., Hutson, L.D., Chien, C.B., and Karlstrom, R.O. (2005) Hedgehog regulated Slit expression determines commissure and glial cell position in the zebrafish forebrain. Development 132(16):3643-3656
Bergeron, S.A., Milla, L.A., Villegas, R., Shen, M.C., Burgess, S.M., Allende, M.L., Karlstrom, R.O., and Palma, V. (2008) Expression profiling identifies novel Hh/Gli-regulated genes in developing zebrafish embryos. Genomics 91(2):165-177
Brand, M., Heisenberg, C.P., Warga, R.M., Pelegri, F., Karlstrom, R.O., Beuchle, D., Picker, A., Jiang, Y.J., Furutani-Seiki, M., van Eeden, F.J., Granato, M., Haffter, P., Hammerschmidt, M., Kane, D.A., Kelsh, R.N., Mullins, M.C., Odenthal, J., and Nüsslein-Volhard, C. (1996) Mutations affecting development of the midline and general body shape during zebrafish embryogenesis. Development 123:129-142
Chandrasekhar, A., Schauerte, H.E., Haffter, P., and Kuwada, J.Y. (1999) The zebrafish detour gene is essential for cranial but not spinal motor neuron induction. Development 126(12):2727-2737
Culverwell, J. and Karlstrom, R.O. (2002) Making the connection: retinal axon guidance in the zebrafish. Sem. Cell Dev. Biol. 13(6):497-506
Devine, C.A., Sbrogna, J.L., Guner, B., Osgood, M., Shen, M.C., and Karlstrom, R.O. (2009) A dynamic Gli code interprets Hh signals to regulate induction, patterning, and endocrine cell specification in the zebrafish pituitary. Dev. Biol. 326(1):143-154
Guner, B., and Karlstrom, R.O. (2007) Cloning of zebrafish nkx6.2 and a comprehensive analysis of the conserved transcriptional response to Hedgehog/Gli signaling in the zebrafish neural tube. Gene Expr. Patterns 7(5):596-605
Haffter, P., Granato, M., Brand, M., Mullins, M.C., Hammerschmidt, M., Kane, D.A., Odenthal, J., van Eeden, F.J., Jiang, Y.J., Heisenberg, C.P., Kelsh, R.N., Furutani-Seiki, M., Vogelsang, E., Beuchle, D., Schach, U., Fabian, C., and Nüsslein-Volhard, C. (1996) The identification of genes with unique and essential functions in the development of the zebrafish. Development 123:1-36
Hammond, K.L., Loynes, H.E., Folarin, A.A., Smith, J., and Whitfield, T.T. (2003) Hedgehog signalling is required for correct anteroposterior patterning of the zebrafish otic vesicle. Development 130(7):1403-1417
Ingham, P.W., and Kim, H.R. (2005) Hedgehog signalling and the specification of muscle cell identity in the Zebrafish embryo. Exp. Cell Res. 306(2):336-342
Karlstrom, R.O., Trowe, T., and Bonhoeffer, F. (1997) Genetic analysis of axon guidance and mapping in the zebrafish. Trends Neurosci. 20(1):3-8
Karlstrom, R.O., Trowe, T., Klostermann, S., Baier, H., Brand, M., Crawford, A.D., Grunewald, B., Haffter, P., Hoffman, H., Meyer, S.U., Muller, B.K., Richter, S., van Eeden, F.J., Nüsslein-Volhard, C., and Bonhoeffer, F. (1996) Zebrafish mutations affecting retinotectal axon pathfinding. Development 123:427-438
Karlstrom, R.O., Tyurina, O.V., Kawakami, A., Nishioka, N., Talbot, W.S., Sasaki, H., and Schier, A.F. (2003) Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development. Development 130(8):1549-1564
Knight, R.D., Mebus, K., and Roehl, H.H. (2008) Mandibular arch muscle identity is regulated by a conserved molecular process during vertebrate development. J. Exp. Zoolog. B Mol. Dev. Evol. 310(4):355-369
Kondoh, H., Uchikawa, M., Yoda, H., Takeda, H., Furutani-Seiki, M., and Karlstrom, R.O. (2000) Zebrafish mutations in Gli-mediated hedgehog signaling lead to lens transdifferentiation from the adenohypophysis anlage. Mech. Dev. 96(2):165-174
Koudijs, M.J., den Broeder, M.J., Groot, E., and van Eeden, F.J. (2008) Genetic analysis of two zebrafish patched homologues identifies novel roles for the hedgehog signaling pathway. BMC Dev. Biol. 8:15
Lewis, K.E. and Eisen, J.S. (2003) From cells to circuits: development of the zebrafish spinal cord. Prog. Neurobiol. 69(6):419-449
Li, Y.X., Yang, H.T., Zdanowicz, M., Sicklick, J.K., Qi, Y., Camp, T.J., and Diehl, A.M. (2007) Fetal alcohol exposure impairs hedgehog cholesterol modification and signaling. Lab. Invest. 87(3):231-240
Loucks, E.J., Schwend, T., and Ahlgren, S.C. (2007) Molecular changes associated with teratogen-induced cyclopia. Birth Defects Res. A Clin. Mol. Teratol. 79(9):642-651
Masai, I., Yamaguchi, M., Tonou-Fujimori, N., Komori, A., and Okamoto, H. (2005) The hedgehog-PKA pathway regulates two distinct steps of the differentiation of retinal ganglion cells: the cell-cycle exit of retinoblasts and their neuronal maturation. Development 132(7):1539-1553
Neuhauss, S.C.F., Biehlmaier, O., Seeliger, M.W., Das, T., Kohler, K., Harris, W.A., and Baier, H. (1999) Genetic disorders of vision revealed by a behavioral screen of 400 essential loci in zebrafish. J. Neurosci. 19(19):8603-8615
Ninkovic, J., Stigloher, C., Lillesaar, C., and Bally-Cuif, L. (2008) Gsk3{beta}/PKA and Gli1 regulate the maintenance of neural progenitors at the midbrain-hindbrain boundary in concert with E(Spl) factor activity. Development 135(18):3137-3148
Odenthal, J., van Eeden, F.J., Haffter, P., Ingham, P.W., and Nüsslein-Volhard, C. (2000) Two distinct cell populations in the floor plate of the zebrafish are induced by different pathways. Dev. Biol. 219(2):350-363
Park, S.W., Davison, J.M., Rhee, J., Hruban, R.H., Maitra, A., and Leach, S.D. (2008) Oncogenic KRAS Induces Progenitor Cell Expansion and Malignant Transformation in Zebrafish Exocrine Pancreas. Gastroenterology 134(7):2080-2090
Paulus, J.D., and Halloran, M.C. (2006) Zebrafish bashful/laminin-alpha1 mutants exhibit multiple axon guidance defects. Dev. Dyn. 235(1):213-224
Piotrowski, T., Schilling, T.F., Brand, M., Jiang, Y.J., Heisenberg, C.P., Beuchle, D., Grandel, H., van Eeden, F.J., Furutani-Seiki, M., Granato, M., Haffter, P., Hammerschmidt, M., Kane, D.A., Kelsh, R.N., Mullins, M.C., Odenthal, J., Warga, R.M., and Nüsslein-Volhard, C. (1996) Jaw and branchial arch mutants in zebrafish. II. Anterior arches and cartilage differentiation. Development 123:345-356
Sanek, N.A., and Grinblat, Y. (2008) A novel role for zebrafish zic2a during forebrain development. Dev. Biol. 317(1):325-335
Sbrogna, J.L., Barresi, M.J., and Karlstrom, R.O. (2003) Multiple roles for Hedgehog signaling in zebrafish pituitary development. Dev. Biol. 254(1):19-35
Schafer, M., Kinzel, D., and Winkler, C. (2007) Discontinuous organization and specification of the lateral floor plate in zebrafish. Dev. Biol. 301(1):117-129
Schäfer, M., Kinzel, D., Neuner, C., Schartl, M., Volff, J.N., and Winkler, C. (2005) Hedgehog and retinoid signalling confines nkx2.2b expression to the lateral floor plate of the zebrafish trunk. Mech. Dev. 122(1):43-56
Sekimizu, K., Nishioka, N., Sasaki, H., Takeda, H., Karlstrom, R.O., and Kawakami, A. (2004) The zebrafish iguana locus encodes Dzip1, a novel zinc-finger protein required for proper regulation of Hedgehog signaling. Development 131(11):2521-2532
Stadler, J.A., Shkumatava, A., and Neumann, C.J. (2004) The role of hedgehog signaling in the development of the zebrafish visual system. Dev. Neurosci. 26(5-6):346-351
Tay, S.Y., Ingham, P.W., and Roy, S. (2005) A homologue of the Drosophila kinesin-like protein Costal2 regulates Hedgehog signal transduction in the vertebrate embryo. Development 132(4):625-634
Teraoka, H., Dong, W., Okuhara, Y., Iwasa, H., Shindo, A., Hill, A.J., Kawakami, A., and Hiraga, T. (2006) Impairment of lower jaw growth in developing zebrafish exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin and reduced hedgehog expression. Aquat. Toxicol. 78(2):103-113
Tyurina, O.V., Guner, B., Popova, E., Feng, J., Schier, A.F., Kohtz, J.D., and Karlstrom, R.O. (2005) Zebrafish Gli3 functions as both an activator and a repressor in Hedgehog signaling. Dev. Biol. 277(2):537-556
Ungos, J.M., Karlstrom, R.O., and Raible, D.W. (2003) Hedgehog signaling is directly required for the development of zebrafish dorsal root ganglia neurons. Development 130(22):5351-5362
Vanderlaan, G., Tyurina, O.V., Karlstrom, R.O., and Chandrasekhar, A. (2005) Gli function is essential for motor neuron induction in zebrafish. Dev. Biol. 282(2):550-570
Whitlock, K.E., Wolf, C.D., and Boyce, M.L. (2003) Gonadotropin-releasing hormone (gnrh) cells arise from cranial neural crest and adenohypophyseal regions of the neural plate in the zebrafish, Danio rerio. Dev. Biol. 257(1):140-152
Wolff, C., Roy, S., and Ingham, P.W. (2003) Multiple muscle cell identities induced by distinct levels and timing of hedgehog activity in the zebrafish embryo. Curr. Biol. 13(14):1169-1181
Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome Res. 15(9):1307-1314
Xu, J., Srinivas, B.P., Tay, S.Y., Mak, A., Yu, X., Lee, S.G., Yang, H., Govindarajan, K.R., Leong, B., Bourque, G., Mathavan, S., and Roy, S. (2006) Genome-wide Expression Profiling in the Zebrafish Embryo Identifies Target Genes Regulated by Hedgehog Signaling During Vertebrate Development. Genetics 174(2):735-752
 
Additional Citations (9):
Phenotype Annotation (1994-2006) (2006) Mutant Data Curated from Older Literature. ZFIN Historical Data
Thisse, C., and Thisse, B. (2005) High Throughput Expression Analysis of ZF-Models Consortium Clones. ZFIN Direct Data Submission :
ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission
ZFIN Staff (2002) Curation of Entrez Gene Database Links. Automated Data Submission
ZFIN Staff (2003) Curation of NCBI Protein Sequence Database Links. Automated Data Submission
ZFIN Staff (2002) Curation of Protein Database Links. Automated Data Submission
ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission
ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation
ZFIN Staff (2003) Submission and Curation of Mutant and Transgenic Lines. ZFIN Direct Data Submission