PUBLICATION
The expression of gbx-2 during zebrafish embryogenesis
- Authors
- Su, Y. and Meng, A.
- ID
- ZDB-PUB-020402-5
- Date
- 2002
- Source
- Mechanisms of Development 113(1): 107-110 (Journal)
- Registered Authors
- Meng, Anming, Su, Ying
- Keywords
- zebrafish; gbx-2; isthmic regions; otic vesicle; telencephalon; diencephalon; pronephric duct; branchial arch
- MeSH Terms
-
- Amino Acid Sequence
- Animals
- Brain/embryology*
- Chick Embryo
- Gene Expression Regulation, Developmental*
- Homeodomain Proteins/biosynthesis*
- Humans
- In Situ Hybridization
- Mice
- Molecular Sequence Data
- RNA, Antisense/biosynthesis
- RNA, Messenger/metabolism
- Sequence Homology, Amino Acid
- Tissue Distribution
- Xenopus Proteins
- Zebrafish
- Zebrafish Proteins
- PubMed
- 11900984 Full text @ Mech. Dev.
Citation
Su, Y. and Meng, A. (2002) The expression of gbx-2 during zebrafish embryogenesis. Mechanisms of Development. 113(1):107-110.
Abstract
Gbx-2 is a homeobox gene essential for normal development of the midbrain and the anterior hindbrain. Zebrafish gbx-2 shares an overall similarity of 67.8, 68.1, 60.6 and 66.5% in amino acid sequence to human, mouse, chick and Xenopus Gbx-2, respectively. The expression of zebrafish gbx-2 is initially, before the completion of epiboly, restricted to the prospective posterior midbrain. The expression remains detectable until the end of pharyngula period. The gbx-2 mRNA is also detected in the otic vesicles, the dorsoposterior telencephalon, the rostral branchial arches, the pronephric duct and median fin fold.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping