Research
General Information
ZIRC
ZFIN ID: ZDB-PERS-030919-5
Kloosterman, Wigard
Plasterk Lab
Hubrecht Laboratory
Netherlands Institute for Developmental Biology
Uppsalalaan 8
Utrecht, 3584CT
Netherlands
Phone: 31-30-2121963 Email: wigard@niob.knaw.nl
FAX: 31-30-2516554 URL:
Biography and Research Interests:

Role of miRNAs and argonaute genes in zebrafish development

Publications:
Li, H., Kloosterman, W., and Fekete, D.M. (2010) MicroRNA-183 Family Members Regulate Sensorineural Fates in the Inner Ear. J. Neurosci.. 30(9):3254-3263
Pase, L., Layton, J.E., Kloosterman, W.P., Carradice, D., Waterhouse, P.M., and Lieschke, G.J. (2009) miR-451 regulates zebrafish erythroid maturation in vivo via its target gata2. Blood.. 113(8):1794-1804
Kapsimali, M., Kloosterman, W.P., de Bruijn, E., Rosa, F., Plasterk, R.H., and Wilson, S.W. (2007) MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system. Genome Biol.. 8(8):R173
Kloosterman, W.P., Lagendijk, A.K., Ketting, R.F., Moulton, J.D., and Plasterk, R.H. (2007) Targeted Inhibition of miRNA Maturation with Morpholinos Reveals a Role for miR-375 in Pancreatic Islet Development. PLoS Biol.. 5(8):e203
Ason, B., Darnell, D.K., Wittbrodt, B., Berezikov, E., Kloosterman, W.P., Wittbrodt, J., Antin, P.B., and Plasterk, R.H. (2006) Differences in vertebrate microRNA expression. Proc. Natl. Acad. Sci. USA. 103(39):14385-14389
Kloosterman, W.P., Steiner, F.A., Berezikov, E., de Bruijn, E., van de Belt, J., Verheul, M., Cuppen, E., and Plasterk, R.H. (2006) Cloning and expression of new microRNAs from zebrafish. Nucleic Acids Res.. 34(9):2558-2569
Kloosterman, W.P., Wienholds, E., de Bruijn, E., Kauppinen, S., and Plasterk, R.H. (2006) In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes. Nat. Methods. 3(1):27-29
Wienholds, E., Kloosterman, W.P., Miska, E., Alvarez-Saavedra, E., Berezikov, E., de Bruijn, E., Horvitz, R.H., Kauppinen, S., and Plasterk, R.H. (2005) MicroRNA Expression in Zebrafish Embryonic Development. Science.. 309(5732):310-311
Kloosterman, W.P., Wienholds, E., Ketting, R.F., and Plasterk, R.H. (2004) Substrate requirements for let-7 function in the developing zebrafish embryo. Nucleic Acids Res.. 32(21):6284-6291

Non-Zebrafish Publications: