Gene

lamc2

ID

ZDB-GENE-110222-3

Name

laminin, gamma 2

Symbol

lamc2 Nomenclature History

Previous Names

sb:eu2427

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa; junctional epidermolysis bullosa Herlitz type; junctional epidermolysis bullosa non-Herlitz type; and lung small cell carcinoma. Is expressed in pancreatic D cell. Orthologous to human LAMC2 (laminin subunit gamma 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

eu2427 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With lamc2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Epidermolysis bullosa, junctional 3A, intermediate	619785
		Epidermolysis bullosa, junctional 3B, severe	619786

Associated With lamc2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000034	Laminin IV
Domain	IPR000742	EGF-like domain
Domain	IPR002049	Laminin-type EGF domain

Domain Details Per Protein

Protein	Length	EGF-like domain	Laminin IV	Laminin-type EGF domain
UniProtKB:A0A8M1RET4 InterPro	1182

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	lamc2-202 (1) Ensembl	Havana	1406 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	lamc2-203 (1) Ensembl	Havana	756 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	lamc2-205 (1) Ensembl	Havana	1287 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	lamc2-004 (1) Ensembl	Havana	608 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations