Gene

gamt

ID
ZDB-GENE-051030-97
Name
guanidinoacetate N-methyltransferase
Symbol
gamt Nomenclature History
Previous Names
  • zgc:123136
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have guanidinoacetate N-methyltransferase activity. Predicted to be involved in creatine biosynthetic process. Predicted to localize to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and guanidinoacetate methyltransferase deficiency. Is expressed in several structures, including digestive system; eye; heart; pleuroperitoneal region; and yolk. Orthologous to human GAMT (guanidinoacetate N-methyltransferase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gamt Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
guanidinoacetate methyltransferase deficiency Alliance Cerebral creatine deficiency syndrome 2 612736
Associated With gamt Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR026480 Arginine N-methyltransferase 2-like domain
Family IPR016550 Guanidinoacetate N-methyltransferase
Homologous_superfamily IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
Domain Details Per Protein
Protein Length Arginine N-methyltransferase 2-like domain Guanidinoacetate N-methyltransferase S-adenosyl-L-methionine-dependent methyltransferase superfamily
UniProtKB:Q71N41 234
UniProtKB:A8E5I0 234
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations