Gene

msx1b

ID
ZDB-GENE-980526-26
Name
muscle segment homeobox 1b
Symbol
msx1b Nomenclature History
Previous Names
  • msh-B
  • mshB
  • msxB
  • msxb (1)
  • etID309829.1 (1)
  • wu:fk04h02
  • zgc:110559
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in several processes, including embryonic organ morphogenesis; fin regeneration; and regulation of neuron apoptotic process. Predicted to localize to nucleus. Is expressed in several structures, including central nervous system; fin; fin bud; germ ring; and median fin fold.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
70 figures from 51 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Phillips et al., 2006
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With msx1b Human Ortholog
No data available
Associated With msx1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR020479 Homeobox domain, metazoa
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox domain, metazoa Homeobox-like domain superfamily
UniProtKB:B2GSG0 257
UniProtKB:Q03356 257
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-msx monoclonal IgG1 , k Mouse
  • IHC
Developmental Studies Hybridoma Bank
6
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations