Research
General Information
ZIRC
ZFIN: Gene: eng1a
ZFIN ID: ZDB-GENE-980526-216

Gene Name:engrailed 1a
Gene Symbol: eng1a
Previous Names: en1, en-1, eng1(1) , zgc:100771
Nomenclature History


GENE EXPRESSION:(current status)
All expression data: 23 figure(s) from 13 publications
Directly submitted expression data: 5 figure(s) (6 images) from Thisse et al., 2004 [IMAGE:7138684]
Wild Type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Hatching:Long-pec (48.00h-60.00h)
  adaxial cell, fast muscle cell ... (all 11)
Curated microarray expression: GEO  (1)

MUTANTS AND TARGETED KNOCKDOWNS:
Mutant line(s):   1 genotype
Allele(s):   T(LG09:dlx1a,dlx2a,eng1a,hoxd4a)b566
Phenotype: (current status)

GENE PRODUCTS:

Gene Ontology
Ontology GO Term
Molecular Function DNA binding (more)
Biological Process multicellular organismal development (more)
Cellular Component nucleus
All GO Terms (8)

Protein Families, Domains and Sites:
  • InterPro:IPR000047 (1)
  • InterPro:IPR000747 (1)
  • InterPro:IPR001356 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR012287 (1)
  • InterPro:IPR015703 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR019549 (1)
  • InterPro:IPR019737 (1)
  • InterPro:IPR020479 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS00033 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF10525 (1)
  • Gene Product Description


    ANTIBODIES:
    Ab-eng (13)


    SEGMENT (CLONE AND PROBE) RELATIONSHIPS:
    eng1a Encodes [EST] IMAGE:7138684 (1)    (order this)
    [cDNA] MGC:100771 (1)    (order this)

    SEQUENCE INFORMATION:
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131045 (1) 1808 bp
    Polypeptide UniProtKB:Q04896 (1) 231 aa
    Sequence Clusters UniGene:75072 (1)
    All Sequence Information (11)

    OTHER  eng1a  GENE / MARKER PAGES:

  • Entrez Gene:30244 (1)
  • Ensembl(Zv8):ENSDARG00000014321 (1)

  • MAPPING INFORMATION:
      LG:  9    Details   View Map: Merged  Individual Panels

    ORTHOLOGY:
      Evidence
    Species Symbol Chromosome (Position) Accession # AA CL
    Zebrafish eng1a  9
    Human EN1  2 (q13-q21)
  • OMIM:131290
  • Entrez Gene:2019
  • Mouse En1  1 (64.10 cM)
  • MGI:95389
  • Entrez Gene:13798
  • Orthology Details

    CITATIONS   (33)