Gene
svep1
- ID
- ZDB-GENE-110726-1
- Name
- sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
- Symbol
- svep1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have calcium ion binding activity. Involved in epidermal cell differentiation and lymph vessel development. Is expressed in fin bud; pharyngeal arch 3-7; and trunk. Orthologous to human SVEP1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Kärpanen et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR013032 | EGF-like, conserved site |
| Conserved_site | IPR018097 | EGF-like calcium-binding, conserved site |
| Domain | IPR000436 | Sushi/SCR/CCP domain |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001881 | EGF-like calcium-binding domain |
| Domain | IPR002035 | von Willebrand factor, type A |
| Domain | IPR003410 | HYR domain |
| Domain | IPR011641 | Tyrosine-protein kinase ephrin type A/B receptor-like |
| Domain | IPR024731 | EGF domain |
| Family | IPR001759 | Pentraxin-related |
| Homologous_superfamily | IPR009030 | Growth factor receptor cysteine-rich domain superfamily |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR035976 | Sushi/SCR/CCP superfamily |
| Homologous_superfamily | IPR036465 | von Willebrand factor A-like domain superfamily |
| PTM | IPR000152 | EGF-type aspartate/asparagine hydroxylation site |
Domain Details Per Protein
| Protein | Length | Concanavalin A-like lectin/glucanase domain superfamily | EGF domain | EGF-like calcium-binding, conserved site | EGF-like calcium-binding domain | EGF-like, conserved site | EGF-like domain | EGF-type aspartate/asparagine hydroxylation site | Growth factor receptor cysteine-rich domain superfamily | HYR domain | Pentraxin-related | Sushi/SCR/CCP domain | Sushi/SCR/CCP superfamily | Tyrosine-protein kinase ephrin type A/B receptor-like | von Willebrand factor A-like domain superfamily | von Willebrand factor, type A |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9QHN0
|
3526 | |||||||||||||||
|
UniProtKB:A0A8M3AU46
|
2217 | |||||||||||||||
|
UniProtKB:A0A8M3BAY6
|
3558 | |||||||||||||||
|
UniProtKB:A0A8M3B423
|
1869 | |||||||||||||||
|
UniProtKB:A0A8M9Q8H8
|
3583 | |||||||||||||||
|
UniProtKB:A0A1D5NSM8
|
3615 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance