Gene

kcnab2b

ID

ZDB-GENE-080219-36

Name

potassium voltage-gated channel subfamily A regulatory beta subunit 2b

Symbol

kcnab2b Nomenclature History

Previous Names

zgc:171453

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to have voltage-gated potassium channel activity. Involved in regulation of action potential and regulation of transmission of nerve impulse. Predicted to localize to cytoplasm and integral component of membrane. Is expressed in Mauthner neurons. Orthologous to human KCNAB2 (potassium voltage-gated channel subfamily A regulatory beta subunit 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Watanabe et al., 2014

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Watanabe et al., 2014
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kcnab2b Human Ortholog

No data available

Associated With kcnab2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR023210	NADP-dependent oxidoreductase domain
Family	IPR005399	Potassium channel, voltage-dependent, beta subunit, KCNAB-related
Family	IPR005400	Potassium channel, voltage-dependent, beta subunit, KCNAB1
Family	IPR005401	Potassium channel, voltage-dependent, beta subunit, KCNAB2
Family	IPR005983	Potassium channel, voltage-dependent, beta subunit, KCNAB
Homologous_superfamily	IPR036812	NADP-dependent oxidoreductase domain superfamily

Domain Details Per Protein

Protein	Length	NADP-dependent oxidoreductase domain	NADP-dependent oxidoreductase domain superfamily	Potassium channel, voltage-dependent, beta subunit, KCNAB	Potassium channel, voltage-dependent, beta subunit, KCNAB1	Potassium channel, voltage-dependent, beta subunit, KCNAB2	Potassium channel, voltage-dependent, beta subunit, KCNAB-related
UniProtKB:A0A8M9PF37 InterPro	346
UniProtKB:E9QGU5 InterPro	412
UniProtKB:A0A8M2B927 InterPro	454
UniProtKB:A0A8M2B9B9 InterPro	397
UniProtKB:A0A8M9PT49 InterPro	379
UniProtKB:A0A8M9PWJ3 InterPro	455
UniProtKB:A0A8M2B970 InterPro	469

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	kcnab2b-201 (1) Ensembl	Havana	1787 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	kcnab2b-202 (1) Ensembl	Havana	1239 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations