Gene
cyp11c1
- ID
- ZDB-GENE-070828-1
- Name
- cytochrome P450, family 11, subfamily C, polypeptide 1
- Symbol
- cyp11c1 Nomenclature History
- Previous Names
-
- cyp11b2
- cyp11b (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have heme binding activity; iron ion binding activity; and oxidoreductase activity. Involved in cortisol metabolic process. Predicted to localize to mitochondrial inner membrane. Is expressed in brain and endocrine system.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 32 figures from 20 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| congenital adrenal hyperplasia | cyp11c1ihb284/ihb284 (AB) | standard conditions | Zhang et al., 2020 |
| congenital adrenal hyperplasia | cyp11c1ihb285/ihb285 (AB) | standard conditions | Zhang et al., 2020 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome P450 | Cytochrome P450, conserved site | Cytochrome P450, E-class, group I | Cytochrome P450 superfamily | Synaphin |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PD87
|
700 | |||||
|
UniProtKB:A1XRK1
|
518 | |||||
|
UniProtKB:A0A8M6YV96
|
701 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available